Suchergebnisse

Busca-se refletir acerca do entrelaçamento entre juventudes negras e o campo do trabalho a partir de perspectivas críticas que interrogam os efeitos da colonialidade e a conjuntura neoliberal, a partir das experiências de atuação protagonizada por jovens negras e negros, moradores de favelas e periferias do Rio de Janeiro. Serão utilizados como ilustração os projetos "Juventudes na Cidade" e "Se Liga no Território!" executados pela organização não-governamental Federação de Órgãos para Assistência Social e Educacional (FASE) nos anos de 2020 e 2021. Toma-se os efeitos da crise pandêmica como pano de fundo para se pensar, à luz da literatura, as expectativas e perspectivas das juventudes negras sobre o trabalho na atualidade. De tal modo, propõe-se o fomento de debates e políticas públicas que articulem os mundos do trabalho, as juventudes negras brasileiras e a luta antirracista.

This paper introduces a methodology for modelling a digital admittance-type distance relay using PSCAD/EMTDC. The proposed distance relay was tested in a simulation of the Brazilian power grid with predetermined fault scenarios. The goal of this paper is to make a detailed evaluation of the mho distance relay. The main aspects include the correct operation of the distance relay, fault resistance effects on the mho characteristics, and the fault detection time of this relay. A new approach to analyse the fault detection time is presented, considering several simulated fault scenarios. The results demonstrate that the fault resistance influences the fault detection time and severely affects the distance relay's general performance. The fault detection time is not constant. It varies within a time interval, considering different fault types, fault locations, and fault resistances. The confidence interval calculation provides a detailed range of the fault detection time, considering its upper and lower limits.

The coronavirus disease (COVID-19) caused by SARS-CoV-2 is creating tremendous human suffering. To date, no effective drug is available to directly treat the disease. In a search for a drug against COVID-19, we have performed a high-throughput X-ray crystallographic screen of two repurposing drug libraries against the SARS-CoV-2 main protease (Mpro), which is essential for viral replication. In contrast to commonly applied X-ray fragment screening experiments with molecules of low complexity, our screen tested already approved drugs and drugs in clinical trials. From the three-dimensional protein structures, we identified 37 compounds that bind to Mpro. In subsequent cell-based viral reduction assays, one peptidomimetic and six non-peptidic compounds showed antiviral activity at non-toxic concentrations. We identified two allosteric binding sites representing attractive targets for drug development against SARS-CoV-2.

EPUB and EPDF available Open Access under CC-BY-NC-ND licence. The COVID-19 pandemic has deeply shaken societies and lives around the world. This powerful book reveals how the pandemic has intensified socio-economic problems and inequalities across the world whilst offering visions for a better future informed by social movements and public sociology. Bringing together experts from 27 countries, the authors explore the global echoes of the pandemic and the different responses adopted by governments, policy makers and activists. The new expressions of social action, and forms of solidarity and protest, are discussed in detail, from the Black Lives Matter protests to the French Strike Movement and the Lebanese Uprising. This is a unique global analysis on the current crisis and the contemporary world and its outcomes