Suchergebnisse

BACKGROUND: Skin diseases constitute up to 40% of all notified occupational diseases in most European countries, predominantly comprising contact dermatitis, contact urticaria, and skin cancer. While insufficient prevention of work-related skin diseases (WRSD) is a top-priority problem in Europe, common standards for prevention of these conditions are lacking. OBJECTIVE: To develop common European standards on prevention and management of WRSD and occupational skin diseases (OSD). METHOD: Consensus amongst experts within occupational dermatology was achieved with regard to the definition of minimum evidence-based standards on prevention and management of WRSD/OSD. RESULTS: By definition, WRSDs/OSDs are (partially or fully) caused by occupational exposure. The definition of OSD sensu stricto additionally includes diverging national legal requirements, with an impact on registration, prevention, management, and compensation. With the implementation of the classification of WRSD/OSD in the International Classification of Diseases (ICD) 11th Revision in future, a valid surveillance and comparability across countries will be possible. Currently, WRDS and OSD are still under-reported. Depending on legislation and regulations, huge differences exist in notification procedures in Europe, although notification is crucial to prevent chronic and relapsing disease. Facilities for early diagnosis, essential for individual patient management, should be based on existing guidelines and include a multidisciplinary approach. Patch testing is essential if contact dermatitis persists or relapses. Workplace exposure assessment of WRSD/OSD requires full labelling of product ingredients on material safety data sheets helping to identify allergens, irritants and skin carcinogens. Comparable standards in primary, secondary and tertiary prevention must be established in Europe to reduce the burden of WRSD/OSD in Europe. CONCLUSION: The adoption of common European standards on prevention of WRSD/OSD will contribute to reduce the incidence of OSD and their socio-economic burden.

This guideline is the result of a systematic literature review using the 'Grading of Recommendations Assessment, Development and Evaluation' (GRADE) methodology and a structured consensus conference held on 28 and 29 November 2012, in Berlin. It is a joint initiative of the Dermatology Section of the European Academy of Allergy and Clinical Immunology (EAACI), the EU-funded network of excellence, the Global Allergy and Asthma European Network (GA(2)LEN), the European Dermatology Forum (EDF), and the World Allergy Organization (WAO) with the participation of delegates of 21 national and international societies. Urticaria is a frequent, mast cell-driven disease, presenting with wheals, angioedema, or both. the life-time prevalence for acute urticaria is approximately 20%. Chronic spontaneous urticaria and other chronic forms of urticaria do not only cause a decrease in quality of life, but also affect performance at work and school and, as such, are members of the group of severe allergic diseases. This guideline covers the definition and classification of urticaria, taking into account the recent progress in identifying its causes, eliciting factors and pathomechanisms. in addition, it outlines evidence-based diagnostic and therapeutic approaches for the different subtypes of urticaria. This guideline was acknowledged and accepted by the European Union of Medical Specialists (UEMS). ; Charite, Allergy Ctr Charite, Dept Dermatol & Allergy, D-10117 Berlin, Germany ; Med Univ Graz, Dept Dermatol, Graz, Austria ; Clin San Carlo, Allergy Clin, Paderno Dugnano, MI, Italy ; Univ Southern Denmark, Odense Univ Hosp, Dept Dermatol & Allergy Ctr, Odense, Denmark ; Med Univ Silesia, Allergol & Clin Immunol Katowice, Dept Internal Dis, Zabrze, Poland ; Univ Genoa, IRCCS AOU SanMartino, Genoa, Italy ; Universidade Federal de São Paulo, Dept Clin Immunol & Allergy, São Paulo, Brazil ; Univ Autonoma Barcelona, Hosp Mar Parc Salut Mar, E-08193 Barcelona, Spain ; Dr DY Patil Med Coll & Hosp, Dept Dermatol, Navi Mumbai, India ; Fac Med, Dermatol Clin, Coimbra, Portugal ; Univ Hosp, Coimbra, Portugal ; Guys & St Thomas Hosp NHS Fdn Trust, St Johns Inst Dermatol, London, England ; Ctr Appl Res Allergy Quebec, Quebec City, PQ, Canada ; Hiroshima Univ, Inst Biomed & Hlth Sci, Dept Dermatol, Hiroshima, Japan ; Med Univ S Carolina, Dept Med, Div Pulm & Crit Care Med, Charleston, SC USA ; Hannover Med Sch, Dept Dermatol & Allergy, Hannover, Germany ; Pantai Hosp Kuala Lumpur, Dept Paediat, Kuala Lumpur, Malaysia ; Univ Hosp Tenon, Dept Dermatol & Allergy, Paris, France ; Johns Hopkins Asthma & Allergy Ctr, Baltimore, MD USA ; Ctr Medicodocente Trinidad, Allergy & Clin Immunol Dept, Caracas, Venezuela ; Univ Hosp, Dept Dermatol, Allergy Unit, Zurich, Switzerland ; Univ Manitoba, Dept Pediat & Child Hlth, Winnipeg, MB R3T 2N2, Canada ; Univ Manitoba, Dept Immunol, Winnipeg, MB, Canada ; Univ Med Ctr Mainz, Dept Dermatol, Mainz, Germany ; Univ Toronto, Div Allergy & Clin Immunol, Toronto, ON, Canada ; Technion, Fac Med, Bnai Zion Med Ctr, Haifa, Israel ; Univ Bari, Dept Biomed Sci & Human Oncol, Unit Dermatol & Venereol, Bari, Italy ; Peking Univ, Hosp 1, Dept Dermatol, Beijing 100871, Peoples R China ; Universidade Federal de São Paulo, Dept Clin Immunol & Allergy, São Paulo, Brazil ; Web of Science

This methods report describes the process of guideline development in detail. It is the result of a systematic literature review using the 'Grading of Recommendations Assessment, Development and Evaluation' (GRADE) methodology and a structured consensus conference held on 28 and 29 November 2012, in Berlin. It is a joint initiative of the Dermatology Section of the European Academy of Allergy and Clinical Immunology (EAACI), the EU-funded network of excellence, the Global Allergy and Asthma European Network (GA(2)LEN), the European Dermatology Forum (EDF), and the World Allergy Organization (WAO) with the participation of delegates of 21 national and international societies. This guideline covers the definition and classification of urticaria, taking into account the recent progress in identifying its causes, eliciting factors and pathomechanisms. in addition, it outlines evidence-based diagnostic and therapeutic approaches for the different subtypes of urticaria. This guideline was acknowledged and accepted by the European Union of Medical Specialists (UEMS) and is published in Allergy 2014; 69:868-887. ; GA2LEN ; EAACI ; Charite, Allergy Ctr Charite, Dept Dermatol & Allergy, Berlin, Germany ; Med Univ Graz, Dept Dermatol, Graz, Austria ; Clin San Carlo, Allergy Clin, Paderno Dugnano, Italy ; Odense Univ Hosp, Dept Dermatol, DK-5000 Odense, Denmark ; Odense Univ Hosp, Allergy Ctr, DK-5000 Odense, Denmark ; Univ Southern Denmark, Odense, Denmark ; Med Univ Silesia, Allergol & Clin Immunol Katowice, Dept Internal Dis, Katowice, Poland ; Univ Genoa, IRCCS AOU SanMartino, Genoa, Italy ; Universidade Federal de São Paulo, São Paulo, Brazil ; Univ Autonoma Barcelona, Hosp Mar Parc Salut Mar, E-08193 Barcelona, Spain ; Dr DY Patil Med Coll & Hosp, Dept Dermatol, Navi Mumbai, India ; Fac Med, Dermatol Clin, Coimbra, Portugal ; Univ Hosp, Coimbra, Portugal ; Guys & St Thomas Hosp NHS Fdn Trust, St Johns Inst Dermatol, London, England ; Ctr Appl Res Allergy Quebec, Quebec City, PQ, Canada ; Hiroshima Univ, Dept Dermatol, Inst Biomed & Hlth Sci, Hiroshima, Japan ; Med Univ S Carolina, Dept Med, Div Pulm & Crit Care Med, Charleston, SC 29425 USA ; Hannover Med Sch, Dept Dermatol & Allergy, Hannover, Germany ; Pantai Hosp Kuala Lumpur, Dept Paediat, Bangsar, Malaysia ; Univ Hosp Tenon, Dept Dermatol & Allergy, Paris, France ; Johns Hopkins Asthma & Allergy Ctr, Baltimore, MD USA ; Ctr Medicodocente Trinidad, Allergy & Clin Immunol Dept, Caracas, Venezuela ; Univ Hosp, Dept Dermatol, Allergy Unit, Zurich, Switzerland ; Univ Manitoba, Dept Pediat & Child Hlth, Winnipeg, MB R3T 2N2, Canada ; Univ Manitoba, Dept Immunol, Winnipeg, MB, Canada ; Univ Med Ctr Mainz, Dept Dermatol, Mainz, Germany ; Univ Toronto, Div Allergy & Clin Immunol, Toronto, ON, Canada ; Technion, Bnai Zion Med Ctr, Fac Med, Haifa, Israel ; Univ Bari, Dept Biomed Sci & Human Oncol, Unit Dermatol & Venereol, Bari, Italy ; Universidade Federal de São Paulo, São Paulo, Brazil ; Web of Science