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This article analyzes the iconic expressions of the memorial quilts for those who have died from AIDS from an anthropological perspective.The purpose of this article is to show how the quilts can be considered ethnographic objects. To do this, the ethnographic documents and materials used (field notes and photographs) are reexamined from participant observation that took place during the exhibition of the quilts in several anti-AIDS events at the end of the 1990s in Mexico City. It is clear that in spite of their weak reception on a local level, they are important cultural manifestations that channeled expressions of grief and political protest on behalf of the people who have died of HIV-AIDS and thereby created a culture of prevention. Furthermore, as ethnographic objects, the quilts contribute valuable qualities and characteristics so that the social construction of the epidemic can be better understood. The quilts' function is also of great importance to understand the diverse groups of human beings and the subcultures that created the quilts' stories that, in turn, solidified a movement to battle AIDS and to fight against homophobia and discrimination within the gay, lesbian, bisexual and transgender community of Mexico City and the world. Finally, by evaluating the current status of AIDS as a "chronic disease," it is suggested that we ethnographically analyze new global and local cultural expressions as they relate to this epidemic. ; Este artículo analiza,desde la perspectiva antropológica, las expresiones iconográficas de las mantas conmemorativas de los muertos por Sida con el propósito de develar su dimensión como objetos etnográficos. Para ello, se retoman los documentos etnográficos elaborados (notas de campo y fotografías) a partir de la observación participante realizada durante la exhibición de las mantas en algunos eventos antisida de finales de los años noventa del siglo pasado en la ciudad de México. Se concluye que las mantas conmemorativas, a pesar de su débil arraigo en el ámbito local, son importantes manifestaciones culturales que canalizaron las expresiones de duelo y protesta política por las personas fallecidas a causa del VIH-Sida, generando con ello una cultura de la prevención. Además, como objetos etnográficos, aportan valiosos elementos para entender la construcción social de la pandemia, a los diversos grupos humanos y a las subculturas que construyeron las historias del movimiento de lucha contra el Sida y del movimiento lésbico, gay, bisexual y transgenérico en la ciudad de México y en el mundo.Finalmente, ante el estatus actual del Sida como "enfermedad crónica", se sugiere analizar etnográficamente las nuevas expresiones culturales globales y locales en torno a esa pandemia.