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Zusammenfassung: Zielsetzung: Personen mit Fluchthintergrund weisen besondere Risiken für substanzbezogene Störungen auf. Zugleich werden sie seltener von Suchthilfeeinrichtungen erreicht. Strategien zur Prävention und Behandlung von Substanzstörungen bei Geflüchteten sind deshalb dringend erforderlich. Methodik: In vier eng miteinander verbundenen Projekten nutzt der PREPARE-Verbund ein Spektrum von methodischen Ansätzen, darunter systematische "Rapid Assessments", die multiple Indikatoren und Informationsquellen kombinieren, qualitative Erhebungen und Interventionsstudien zur Prävention und Behandlung. Ergebnisse: PREPARE wird systematisch Erkenntnisse zu Substanzproblemen bei Geflüchteten in Deutschland bereitstellen, Strategien zu guter Praxis für Suchtprävention und -behandlung identifizieren, einen Beitrag zu einer verbesserten Diagnostik von Substanzproblemen bei Geflüchteten leisten und innovative Interventionen zur indizierten Prävention von substanzbezogenen Störungen und zur integrativen Behandlung von Betroffenen mit Traumatisierungen und substanzbezogenen Störungen entwickeln. Weiter wird ein nationales webbasiertes Ressourcenzentrum in Zusammenarbeit mit der Deutschen Hauptstelle für Suchtfragen (DHS) aufgebaut. Schlussfolgerungen: Geflüchtete mit substanzbezogenen Störungen weisen besondere Bedarfe in Bezug auf den Zugang zu Angeboten der Suchthilfe und die Art der Hilfen auf. Der PREPARE-Verbund soll dazu beitragen, diese besonders vulnerable Gruppe besser zu versorgen.

Background/Aims: Maltreatment in childhood and adolescence is a risk factor for substance use disorders (SUDs) in adulthood. This association has rarely been investigated in the light of emotion dysregulation. To fill this gap, this study examines emotion dysregulation and SUDs among adults with a history of early maltreatment. Methods: Comparison of emotion dysregulation in adults with a history of early abuse and neglect who developed either an SUD (n = 105) or no mental disorder (n = 54). Further, a mediation model for the association between the severity of early maltreatment and SUDs was tested. Participants completed research diagnostic interviews for psychopathology, the Difficulties in Emotion Regulation Scale, and the Childhood Trauma Questionnaire. Results: By using hierarchical regression techniques and mediational analyses controlling for age and gender, it was possible to provide evidence for the mediating role of emotion dysregulation between early emotional and physical maltreatment and later SUDs. Conclusions: Emotion dysregulation is a potential mechanism underlying the relationship between early emotional and physical maltreatment and the development of SUDs. In light of these findings, focusing on the early training of adaptive emotion regulation strategies after childhood maltreatment might be of considerable relevance to prevent the development of SUDs.

<b><i>Background:</i></b> Self-stigma is a result of internalizing negative stereotypes by the affected person. Research on self-stigma in substance use disorders (SUD) is still scarce, especially regarding the role of childhood trauma and subsequent posttraumatic disorders. <b><i>Objectives:</i></b> The present study investigated the progressive model of self-stigma in women with SUD and posttraumatic stress disorder (PTSD), and the predictive value of PTSD severity and childhood trauma experiences on self-stigma. <b><i>Method:</i></b> In a cross-sectional study with 343 women with SUD and PTSD, we used the Self-Stigma in Alcohol Dependency Scale, the Childhood Trauma Questionnaire (CTQ), the PTSD Symptom Scale Interview (PSS-I), and to control for SUD severity and depression, the Addiction Severity Index Lite and the Beck Depression Inventory-II. Hierarchical regression analyses were conducted for each stage of self-stigma (<i>aware-agree-apply-harm</i>). <b><i>Results:</i></b> The interrelated successive stages of self-stigma were largely confirmed. In the regression models, no significant effects of the PSS-I- and the CTQ-scores were observed at any stage of self-stigma. <i>Agreeing</i> with negative stereotypes was solely predicted by younger age, <i>applying</i> these stereotypes to oneself was higher in women with younger age, higher depression and SUD severity, and suffering from the application (<i>harm</i>) was only predicted by depression. <b><i>Conclusions:</i></b> The progressive model of self-stigma could be confirmed in women with SUD and PTSD, but PTSD severity and childhood trauma did not directly affect this process. Self-stigma appears to be related to depression in a stronger way than PTSD is related to women with SUD and PTSD.