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S3 guideline urticaria. Part 1: Classification and diagnosis of urticaria: German language version of the international S3-guideline
Urticaria is a frequent disease. The lifetime prevalence for urticaria is approximately 20%. Urticaria not only causes a decrease in quality of life, but also affects performance at work and school and, as such, is a member of the group of severe allergic diseases. This guideline covers the definition and classification of urticaria, taking into account the recent progress in identifying its causes, eliciting factors, and pathomechanisms. In addition, it outlines evidence-based approaches to economical diagnosis for different subtypes of urticaria. The correct management of urticaria, which is of paramount importance for patients, is very complex and is consequently covered in a separate guideline. This German language guideline was prepared on the basis of the international English language guideline, which was acknowledged by UEMS (European Union of Medical Specialists), taking into account medical conditions in the German language area. This guideline, together with its sister guideline on the management of urticaria, is the result of a consensus reached during a panel discussion at the 3rd International Consensus Meeting on Urticaria, "Urticaria 2008", a joint initiative of the Dermatology Section of the EAACI (European Academy of Allergy and Clinical Immunology), the EU-funded network of excellence GA(2)LEN (Global Allergy and Asthma European Network), the EDF (European Dermatology Forum) and the WAO (World Allergy Organization). For the first time, given that evidence was sufficient, the Grading-of-Recommendations-Assessment- De vel opment-and- Evaluation-(GRADE)-Method was used here as far as possible.
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S3 guideline urticaria. Part 1: Classification and diagnosis of urticaria: German language version of the international S3-guideline
In: Zuberbier, T., Aberer, W., Brockow, K., Grabbe, J., Hamelmann, E., Hartmann, K., Jakob, T., Merk, H. F., Ollert, M., Rueff, F., Schmid-Grendelmeier, P., Staubach, P., Voigtmann, I., Wedi, B. and Maurer, M. (2011). S3 guideline urticaria. Part 1: Classification and diagnosis of urticaria: German language version of the international S3-guideline. Allergologie, 34 (12). S. 569 - 581. DEISENHOFEN-MUENCHEN: DUSTRI-VERLAG DR KARL FEISTLE. ISSN 0344-5062
Urticaria is a frequent disease. The lifetime prevalence for urticaria is approximately 20%. Urticaria not only causes a decrease in quality of life, but also affects performance at work and school and, as such, is a member of the group of severe allergic diseases. This guideline covers the definition and classification of urticaria, taking into account the recent progress in identifying its causes, eliciting factors, and pathomechanisms. In addition, it outlines evidence-based approaches to economical diagnosis for different subtypes of urticaria. The correct management of urticaria, which is of paramount importance for patients, is very complex and is consequently covered in a separate guideline. This German language guideline was prepared on the basis of the international English language guideline, which was acknowledged by UEMS (European Union of Medical Specialists), taking into account medical conditions in the German language area. This guideline, together with its sister guideline on the management of urticaria, is the result of a consensus reached during a panel discussion at the 3rd International Consensus Meeting on Urticaria, Urticaria 2008, a joint initiative of the Dermatology Section of the EAACI (European Academy of Allergy and Clinical Immunology), the EU-funded network of excellence GA(2)LEN (Global Allergy and Asthma European Network), the EDF (European Dermatology Forum) and the WAO (World Allergy Organization). For the first time, given that evidence was sufficient, the Grading-of-Recommendations-Assessment- De vel opment-and- Evaluation-(GRADE)-Method was used here as far as possible.
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Perspectives in allergen immunotherapy: 2017 and beyond
The Future of the Allergists and Specific Immunotherapy (FASIT) workshop provides a regular platform for global experts from academia, allergy clinics, regulatory authorities and industry to review developments in the field of allergen immunotherapy (AIT). The most recent meeting, held in February 2017, had two main themes: advances in AIT and hot topics in AIT from the regulatory point of view. The first theme covered opportunities for personalised AIT, advances in adjuvants and delivery systems, and the development of new molecules and future vaccines for AIT. Key topics in the second part of the meeting were the effects of the enactment of European Directive 2001/83 on the availability of allergens for therapy and diagnosis across the EU, the challenges of conducting Phase III studies in the field, the future role of allergen exposure chambers in AIT-studies, and specific considerations in performing AIT-studies in the paediatric population. Finally, the group highlighted the forthcoming EAACI guidelines and their particular importance for the standardisation of practice in the treatment of allergies. This supplement presents a comprehensive insight into those panel discussions and highlights unmet needs and also possible solutions to them for the future.
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