Getting older goes hand in hand with losses of many kinds-ending careers, empty nests, illness, the deaths of loved ones-and this book by one of the world's most beloved grief experts helps one acknowledge and mourn the many losses of aging while also offering advice for living better in old age. The 100 practical tips and activities address the emotional, spiritual, cognitive, social, and physical needs of seniors who want to age authentically and gracefully, and each idea also includes a seize-the-day action to live fully and with joy in the present moment. For those who've just entered thei
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Navigating the challenging journey that families and friends of Alzheimer's patients must endure, this heartfelt guide reveals how their struggle is as complex and drawn out as the illness itself. Confronting their natural but difficult process of grieving and mourning, the study covers the inevitable feelings of shock, sadness, anger, guilt, and relief, illustrating the initial reactions people commonly feel from the moment of the dementia's onset. Healthy and productive ways to acknowledge and express these feelings are suggested along with 100 tips and activities that fulfill the emotional
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Shows that taboo-making has its own logic in promoting and balancing the total human environment within a cultural system, and that sometimes new taboos arise in response to serious imbalances within social and environmental structures. Analyses a recent prohibition against the eating of frogmeat among the Anufo of Northern Ghana showing how the prohibition relates to recent changes in their society. Also traces some inter-related anthropological ideas about myth, ritual and taboo. (GAW)
The most recent attempt to define the ideological structure of Amer colonial pol has been the theory of 'deference.' Borrowing the term from the Victorian writer, Walter Bagehot, modern scholars such as J. R. Pole & Bernard Bailyn have used the idea in explaining why colonial masses accepted a pol'al leadership dominated by elites of the upper econ & SC's. In a number of respects, the deference analysis has helped to free scholars from the limited conceptions established earlier by 'Whig,' 'Progressive,' & 'Neo-Whig' historians. Yet the theory falls short of providing a complete understanding of colonial pot by its failure to show that deferential pol'al & soc att's were actually held by a majority of colonial Amer's. Studies done by younger scholars such as Jesse Lemisch on the pol'al att's & beliefs of the colonial Le's modify many of the deference theory's claims. Utilizing the methods of pol'al sci'ts, anthrop'ts & psychol'ts, what is newly required is a more sophisticated approach aimed at showing the interrelationship between the pol'al & soc thought of Uc & ML c's in colonial America. IPSA.
AbstractWe introduce new data resources to enable spatial and nonspatial research on Canadian elections, electoral history and political geography. These include a comprehensive set of distinct identification codes for every federal electoral district in Canada from 1867 to the present, a complete set of digital boundary files for these electoral districts, historical census data aggregated to federal electoral districts, and tools to connect our district identification codes to federal election results. After describing the construction and content of these new resources, we provide an example of their use in a comparative-historical analysis of district compactness in Canada and the United States. We find that, in contrast to the United States, postwar institutional changes to district boundary-drawing processes had little effect on district compactness in Canada.
Abstract. We perform numerical simulations of the coastal impact of large co-seismic tsunamis, initiated in the Puerto Rican trench, both in far-field areas along the upper US East coast (and other Caribbean islands), and in more detail in the near-field, along the Puerto Rico North Shore (PRNS). We first model a magnitude 9.1 extreme co-seismic source and then a smaller 8.7 magnitude source, which approximately correspond to 600 and 200 year return periods, respectively. In both cases, tsunami generation and propagation (both near- and far-field) are first performed in a coarse 2′ basin scale grid, with ETOPO2 bathymetry, using a fully nonlinear and dispersive long wave tsunami model (FUNWAVE). Coastal runup and inundation are then simulated for two selected areas, using finer coastal nested grids. Thus, a 15″ (450 m) grid is used to calculate detailed far-field impact along the US East Coast, from New Jersey to Maine, and a 3″ (90 m) grid (for the finest resolution), encompassing the entire PRNS, is used to compute detailed near-field impact along the PRNS (runup and inundation). To perform coastal simulations in nested grids, accurate bathymetry/topography databases are constructed by combining ETOPO2 2′ data (in deep water) and USGS' or NOAA's 15″ or 3″ (in shallow water) data. In the far-field, runup caused by the extreme 9.1 source would be severe (over 10 m) for some nearby Caribbean islands, but would only reach up to 3 m along the selected section of the East coast. A sensitivity analysis to the bathymetric resolution (for a constant 3″ model grid) of runup along the PRNS, confirms the convergence of runup results for a topographic resolution 24″ or better, and thus stresses the importance of using sufficiently resolved bathymetric data, in order to accurately predict extreme runup values, particularly when bathymetric focusing is significant. Runup (10–22 m) and inundation are found to be very large at most locations for the extreme 9.1 source. Both simulated spatial inundation snapshots and time series indicate, the inundation would be particularly severe near and around the low-lying city of San Juan. For the 8.7 source, runup along the PRNS would be much less severe (3–6 m), but still significant, while inundation would only be significant near and around San Juan. This first-order tsunami hazard analysis stresses the importance of conducting more detailed and comprehensive studies, particularly of tsunami hazard along the PRNS, for a more complete and realistic selection of sources; such work is ongoing as part of a US funded (NTHMP) tsunami inundation mapping effort in Puerto Rico.
Abstract. Case studies of landslide tsunamis require integration of marine geology data and interpretations into numerical simulations of tsunami attack. Many landslide tsunami generation and propagation models have been proposed in recent time, further motivated by the 1998 Papua New Guinea event. However, few of these models have proven capable of integrating the best available marine geology data and interpretations into successful case studies that reproduce all available tsunami observations and records. We show that nonlinear and dispersive tsunami propagation models may be necessary for many landslide tsunami case studies. GEOWAVE is a comprehensive tsunami simulation model formed in part by combining the Tsunami Open and Progressive Initial Conditions System (TOPICS) with the fully non-linear Boussinesq water wave model FUNWAVE. TOPICS uses curve fits of numerical results from a fully nonlinear potential flow model to provide approximate landslide tsunami sources for tsunami propagation models, based on marine geology data and interpretations. In this work, we validate GEOWAVE with successful case studies of the 1946 Unimak, Alaska, the 1994 Skagway, Alaska, and the 1998 Papua New Guinea events. GEOWAVE simulates accurate runup and inundation at the same time, with no additional user interference or effort, using a slot technique. Wave breaking, if it occurs during shoaling or runup, is also accounted for with a dissipative breaking model acting on the wave front. The success of our case studies depends on the combination of accurate tsunami sources and an advanced tsunami propagation and inundation model.
Importance Juvenile amyotrophic lateral sclerosis (ALS) is a rare form of ALS characterized by age of symptom onset less than 25 years and a variable presentation. Objective To identify the genetic variants associated with juvenile ALS. Design, Setting, and Participants In this multicenter family-based genetic study, trio whole-exome sequencing was performed to identify the disease-associated gene in a case series of unrelated patients diagnosed with juvenile ALS and severe growth retardation. The patients and their family members were enrolled at academic hospitals and a government research facility between March 1, 2016, and March 13, 2020, and were observed until October 1, 2020. Whole-exome sequencing was also performed in a series of patients with juvenile ALS. A total of 66 patients with juvenile ALS and 6258 adult patients with ALS participated in the study. Patients were selected for the study based on their diagnosis, and all eligible participants were enrolled in the study. None of the participants had a family history of neurological disorders, suggesting de novo variants as the underlying genetic mechanism. Main Outcomes and Measures De novo variants present only in the index case and not in unaffected family members. Results Trio whole-exome sequencing was performed in 3 patients diagnosed with juvenile ALS and their parents. An additional 63 patients with juvenile ALS and 6258 adult patients with ALS were subsequently screened for variants in the SPTLC1 gene. De novo variants in SPTLC1 (p.Ala20Ser in 2 patients and p.Ser331Tyr in 1 patient) were identified in 3 unrelated patients diagnosed with juvenile ALS and failure to thrive. A fourth variant (p.Leu39del) was identified in a patient with juvenile ALS where parental DNA was unavailable. Variants in this gene have been previously shown to be associated with autosomal-dominant hereditary sensory autonomic neuropathy, type 1A, by disrupting an essential enzyme complex in the sphingolipid synthesis pathway. Conclusions and Relevance These data broaden the phenotype associated with SPTLC1 and suggest that patients presenting with juvenile ALS should be screened for variants in this gene.