Arbeitsplätze und Berufe: Kinder einer Grundschulklasse erkunden ihren Stadtteil
In: Arbeiten + lernen: a + l ; Unterricht im Lernfeld Arbeitslehre. Technik, Band 8, Heft 29, S. 12-15
ISSN: 0941-536X
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In: Arbeiten + lernen: a + l ; Unterricht im Lernfeld Arbeitslehre. Technik, Band 8, Heft 29, S. 12-15
ISSN: 0941-536X
In: Public health genomics, Band 22, Heft 1-2, S. 8-15
ISSN: 1662-8063
Health systems around the world seek to address patients' unmet health needs for a range of acute and chronic diseases. Simultaneously, governments strive to keep healthcare spending sustainable, while providing equal access to high-quality care. This has fuelled debate around what constitutes a valuable healthcare intervention in a health system and the corollary consideration of what governments are willing to pay for a certain health intervention. Until recently, the value of information in general, and the value of diagnostic information (VODI) specifically, was not part of the discussion.<sup></sup>However, investment in diagnostic information can be a key development as information may guide more effective and efficient healthcare and help maintain an affordable health system. This paper therefore explores ways to best define, evaluate, and reward the value created from diagnostics in healthcare and how to include these value considerations in decision-making processes for diagnostics. The authors ultimately call for a holistic VODI framework that accounts for the full range of potential benefits of diagnostic testing, beyond the traditional clinical and health economic domains, and that is essential to recognise, measure, and fully leverage the benefits of diagnostics for patients, health systems, and society.
Advances in high-throughput genomic technologies coupled with a growing number of genomic results potentially useful in clinical care have led to ground-breaking genomic medicine implementation programs in various nations. Many of these innovative programs capitalize on unique local capabilities arising from the structure of their health care systems or their cultural or political milieu, as well as from unusual burdens of disease or risk alleles. Many such programs are being conducted in relative isolation and might benefit from sharing of approaches and lessons learned in other nations. The National Human Genome Research Institute recently brought together 25 of these groups from around the world to describe and compare projects, examine the current state of implementation and desired near-term capabilities, and identify opportunities for collaboration to promote the responsible implementation of genomic medicine.
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In: Manolio , T A , Abramowicz , M , Al-Mulla , F , Anderson , W , Balling , R , Berger , A C , Bleyl , S , Chakravarti , A , Chantratita , W , Chisholm , R L , Dissanayake , V H W , Dunn , M , Dzau , V J , Han , B G , Hubbard , T , Kolbe , A , Korf , B , Kubo , M , Lasko , P , Leego , E , Mahasirimongkol , S , Majumdar , P P , Matthijs , G , McLeod , H L , Metspalu , A , Meulien , P , Miyano , S , Naparstek , Y , O'Rourke , P P , Patrinos , G P , Rehm , H L , Relling , M V , Rennert , G , Rodriguez , L L , Roden , D M , Shuldiner , A R , Sinha , S , Tan , P , Ulfendahl , M , Ward , R , Williams , M S , Wong , J E L , Green , E D & Ginsburg , G S 2015 , ' Global implementation of genomic medicine : We are not alone ' , Science Translational Medicine , vol. 7 , no. 290 , 290ps13 . https://doi.org/10.1126/scitranslmed.aab0194
Around the world, innovative genomic-medicine programs capitalize on singular capabilities arising from local health care systems, cultural or political milieus, and unusual selected risk alleles or disease burdens. Such individual eforts might beneft from the sharing of approaches and lessons learned in other locales. The U.S. National Human Genome Research Institute and the National Academy of Medicine recently brought together 25 of these groups to compare projects, to examine the current state of implementation and desired near-term capabilities, and to identify opportunities for collaboration that promote the responsible practice of genomic medicine. Eforts to coalesce these groups around concrete but compelling signature projects should accelerate the responsible implementation of genomic medicine in eforts to improve clinical care worldwide.
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In: http://orbilu.uni.lu/handle/10993/26641
Around the world, innovative genomic-medicine programs capitalize on singular capabilities arising from local health care systems, cultural or political milieus, and unusual selected risk alleles or disease burdens. Such individual efforts might benefit from the sharing of approaches and lessons learned in other locales. The U.S. National Human Genome Research Institute and the National Academy of Medicine recently brought together 25 of these groups to compare projects, to examine the current state of implementation and desired near-term capabilities, and to identify opportunities for collaboration that promote the responsible practice of genomic medicine. Efforts to coalesce these groups around concrete but compelling signature projects should accelerate the responsible implementation of genomic medicine in efforts to improve clinical care worldwide.
BASE