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THE FULL U.S. SENATE WILL CONSIDER THE STRATEGIC ARMS REDUCTION COMMITTEE (START) AT A TIME OF NATIONAL REASSESSMENT WHICH INVARIABLE COMES AFTER A NATIONAL ELECTION. THE SENATE'S CONSIDERATION WILL PRESENT A UNIQUE OPPORTUNITY TO SET THINGS RIGHT WITH START, TO SAFEGUARD AMERICAN SECURITY AND GLOBAL STABILTIY, AND TO ESTABLISH THE ENDURING FOUNDATION OF A NEW STRATEGIC FRAMEWORK FOR THE POST-COLD WAR ERA. AFTER SUGGESTING SEVEN SAFEGUARDS FOR THE SENATE THIS ARTICLE SUGGESTS THAT ONLY WITH THE ESTABLISHMENT OF A NEW STRATEGIC FRAMEWORK AND A NEW GRAND BARGAIN CAN THE FREEDOM AND SECURITY OF AMERICA AND THE WORLD BE SAFEGUARDED FOR FUTURE GENERATIONS.

A new synthetic platform for the spatially controlled functionalization of phase separated block copolymer nanoparticles is presented. Selective incorporation of chemical functionalities into specific domains of striped ellipsoidal nanoparticles is achieved by blending a structure-inducing PS-b-P2VP block copolymer with functionalized PS-co-X and P2VP-co-X copolymers. During self-assembly, the BCP phases incorporate the corresponding functional copolymers which results in their chemical modification without losing control over particle shape and morphology. It was shown that the introduction of benzophenones as photocrosslinking groups allows the preparation of particles which demonstrated a reversible shape change due to triggered swelling/deswelling. This dynamic behavior could be combined with the selective introduction of other moieties such as ferrocene groups or reactive pentafluorostyrene moieties. Ultimately, such combinations opened up new opportunities for post-assembly functionalizations to realize multifunctional particles containing for example ferrocene moieties in the PS domains and Au nanoparticles in the P2VP phase. Overall, a versatile toolbox was developed that enables the formation of tailor-made functional shape anisotropic nanoparticles. ; This work was supported partly by the MRSEC Program of the National Science Foundation (NSF) under Award DMR-1121053 (S. K.), the Institute for Collaborative Biotechnologies through grant W911NF-09-0001 from the U.S. Army Research Office (B. V. K. J. S., D. K), and the National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, under Contract no. HHSN268201000046C (D. K. and C. W.). Facilities support from the CNSI-MRL Center for Scientific Computing (DMR-1121053 and CNS-0960316) is acknowledged. The content of the information does not necessarily reflect the position or the policy of the US government and no official endorsement should be inferred. B. V. K. J. S. was supported by a fellowship within the Postdoc-Program of the German Academic Exchange Service (DAAD).