Suchergebnisse

Genetic predispositions play an important role in the development of internalizing and externalizing behaviors. Understanding the mechanisms through which genetic risk unfolds to influence these developmental outcomes is critical for developing prevention and intervention efforts, capturing key elements of Irv's research agenda and scientific legacy. In this study, we examined the role of parenting and personality in mediating the effect of genetic risk on adolescents' major depressive disorder and conduct disorder symptoms. Longitudinal data were drawn from a sample of 709 European American adolescents and their mothers from the Collaborative Studies on Genetics of Alcoholism. Results from multivariate path analysis indicated that adolescents' depressive symptoms genome-wide polygenic scores (DS_GPS) predicted lower parental knowledge, which in turn was associated with more subsequent major depressive disorder and conduct disorder symptoms. Adolescents' DS_GPS also had indirect effects on these outcomes via personality, with a mediating effect via agreeableness but not via other dimensions of personality. Findings revealed that the pattern of associations was similar across adolescent gender. Our findings emphasize the important role of evocative gene–environment correlation processes and intermediate phenotypes in the pathways of risk from genetic predispositions to complex adolescent outcomes.

The current study tested whether COVID-19 disruptions and perceived discrimination were related to mental health (i.e., posttraumatic stress disorder [PTSD] symptoms and emotional, psychological, and social well-being), and whether exercise moderated relations. Additionally, we tested whether findings varied by ethnicity/race. Participants were 368 African American and Asian American emerging adults ( Mage = 19.92, SD = .34). Findings did not vary by ethnicity/race. COVID-19 disruptions predicted poorer emotional, psychological, and social well-being, and more PTSD symptoms. Discrimination predicted more PTSD symptoms. Exercise was associated with better emotional, psychological, and social well-being, and moderated the relation between COVID-19 disruptions and emotional well-being. At low levels of exercise, COVID-19 disruptions predicted poorer emotional well-being, but this relation was not significant at high levels of exercise. Findings highlight that discrimination and disruptions during the pandemic negatively affect African American and Asian American emerging adults' mental health, but that exercise plays an important protective role.