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The U.S. Department of Energy (DOE) established the Microbial Genome Program in 1994. A principal goal of this project is to determine the complete genome sequence of a number of microbes that may be useful to DOE in carrying out its missions (including to produce energy sources, sequester excess atmospheric carbon affecting global climate, and to clean up contaminated environments).Within the framework of the Microbial Genome Program over 50 genomes have been draft sequenced at the Joint Genome Institute. These genomes, as well as 5 finished ones are available at http://www.jgi.doe.gov/JGI_microbial/html/index.html. These pages contain background and collaborator information for each microbe, genome browsers, blast pages, assembly statistics, and a sequence download ftp site that is freely available for government, academic, medical, and industrial scientists. Many of these microbes have been sequenced in response to a DOE "Request for Suggestions" (http://www.sc.doe.gov/ober/microbial.html), a program where individual researchers may propose specific microbes for genome sequencing projects at the JGI.Large-scale sequencing of entire microbial genomes has opened a new era in biology, but the greatest challenge will be to define gene function and complex regulatory networks at the whole-genome level. DOE's Genomes to Life program will use DNA sequences from microbes and higher organisms to study the essential processes of living systems. Advanced technological and computational resources will help to identify and understand the underlying mechanisms that enable organisms to develop, survive, carry out their normal functions, and reproduce under myriad environmental conditions.

Abstract The genus Marinobacterium belongs to the family Alteromonadaceae within the class Gammaproteobacteria and was reported in 1997. Currently the genus Marinobacterium contains 16 species. Marinobacterium rhizophilum CL-YJ9T was isolated from sediment associated with the roots of a plant growing in a tidal flat of Youngjong Island, Korea. The genome of the strain CL-YJ9T was sequenced through the Genomic Encyclopedia of Type Strains, Phase I: KMG project. Here we report the main features of the draft genome of the strain. The 5,364,574 bp long draft genome consists of 58 scaffolds with 4762 protein-coding and 91 RNA genes. Based on the genomic analyses, the strain seems to adapt to osmotic changes by intracellular production as well as extracellular uptake of compatible solutes, such as ectoine and betaine. In addition, the strain has a number of genes to defense against oxygen stresses such as reactive oxygen species and hypoxia. ; This work was performed under the auspices of the US Department of Energy's Office of Science, Biological and Environmental Research Program, and by the University of California, Lawrence Berkeley National Laboratory under contract No. DE-AC02-05CH11231. This work was also supported in part by a research program (PE99513) of the Korea Institute of Ocean Science and Technology (KIOST) and by an East Asian Seas Time series-1 (EAST-1) funded by the Ministry of Oceans and Fisheries, Korea, and the BK21+ project of the Korean Government