Suchergebnisse

In British Columbia, forest tenure holders have the obligation to reforest harvested areas, and the government invests in regeneration in areas damaged by wildfire or mountain pine beetle (MPB). Direct seeding (or direct sowing) is a process by which woodlands are established or re-established by sowing tree seeds at their final growing location. Direct seeding is being re-introduced in BC as an alternative to planting. Many factors affect the emergence and survival of seedlings, including temperature, precipitation, soil structure, predation and vegetation competition, all of which interact with the biological characteristics of the tree species. In field trials, site selection, site preparation, seed selection, vegetation control, increasing seeding density, sowing with alternate foods, and sowing with cover crop have been shown to improve seedling establishment. . However, the effectiveness of these techniques may vary with species, local environment, and location. Therefore, more research is needed before direct seeding can be applied broadly for regeneration in BC. Specific recommendations include: 1) more field trials; 2) enhanced communication and cooperation among research agencies and licencee holders; 3) modelling of germination response to varying conditions; 4) reduction in seed cost; and, 5) improvements in machine efficiency. ; Forestry, Faculty of ; Unreviewed ; Undergraduate

AbstractAdenomyosis is a benign gynecological disease. The pathogenesis of adenomyosis is still unclear. The Hippo signaling pathway is highly conserved in vivo and associated with endometriosis and various cancers. Our objective was to study the expression of Hippo signaling pathway–related proteins in the uterus of mice with and without adenomyosis. We also sought to determine the relationship between the Hippo signaling pathway and cell migration, invasion, proliferation, and apoptosis in adenomyosis. The inactivation of Hippo signaling pathway and abnormal expression of EMT-related proteins were observed in mice with adenomyosis. In vitro, the YAP inhibitor verteporfin can inhibit the proliferation and migration of Ishikawa cells and promote apoptosis, while inhibiting the EMT process. In addition, intraperitoneal injection of verteporfin inhibits EMT process and proliferation and promotes apoptosis of cells in the uterus of adenomyosis mice. It suggests that the Hippo signaling pathway participates in the EMT, proliferation, and apoptosis of cells in adenomyosis. In conclusion, these results suggest that Hippo signaling pathway may be involved in the development of adenomyosis by regulating EMT, proliferation, and apoptosis of cells, which provide a potential target for the treatment of adenomyosis.