Modeling of the Homeless Population in Louisiana and Introduction of Food Forests in Baton Rouge as a Means of Mitigating Homelessness
In: Current Urban Studies, Band 11, Heft 3, S. 474-496
ISSN: 2328-4919
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In: Current Urban Studies, Band 11, Heft 3, S. 474-496
ISSN: 2328-4919
This paper identifies the mechanism by which patients with multiple sclerosis develop secondary autoimmunity after treatment with the lymphocyte-depleting humanized monoclonal antibody alemtuzumab (Campath-1H). In identifying this mechanism, it shows that T-cell homeostatic proliferation can lead to autoimmunity in humans. Alemtuzumab is one of the most effective treatments of multiple sclerosis tested to date; it is currently licensed in the European Union and under consideration by the Food and Drug Administration. Understanding what drives its most significant side effect is of clear clinical importance.
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