As professionals concerned for people with dementia today and dedicated to finding more effective treatment and prevention for dementia tomorrow, we value our membership of the European Union (EU) and are deeply concerned by the prospect of the UK exiting. The EU has made dementia research a priority and has made substantial funds available for research that is driving faster, more effective clinical trials that are our best hope of finding a disease-modifying therapy. With its strong science and translational research base, the UK is making a considerable contribution to these studies.
The Dementias Platform UK Data Portal is a data repository facilitating access to data for 3 370 929 individuals in 42 cohorts. The Data Portal is an end-to-end data management solution providing a secure, fully auditable, remote access environment for the analysis of cohort data. All projects utilising the data are by default collaborations with the cohort research teams generating the data. The Data Portal uses UK Secure eResearch Platform infrastructure to provide three core utilities: data discovery, access, and analysis. These are delivered using a 7 layered architecture comprising: data ingestion, data curation, platform interoperability, data discovery, access brokerage, data analysis and knowledge preservation. Automated, streamlined, and standardised procedures reduce the administrative burden for all stakeholders, particularly for requests involving multiple independent datasets, where a single request may be forwarded to multiple data controllers. Researchers are provided with their own secure 'lab' using VMware which is accessed using two factor authentication. Over the last 2 years, 160 project proposals involving 579 individual cohort data access requests were received. These were received from 268 applicants spanning 72 institutions (56 academic, 13 commercial, 3 government) in 16 countries with 84 requests involving multiple cohorts. Projects are varied including multi-modal, machine learning, and Mendelian randomisation analyses. Data access is usually free at point of use although a small number of cohorts require a data access fee.
International audience ; The Dementias Platform UK Data Portal is a data repository facilitating access to data for 3 370 929 individuals in 42 cohorts. The Data Portal is an end-to-end data management solution providing a secure, fully auditable, remote access environment for the analysis of cohort data. All projects utilising the data are by default collaborations with the cohort research teams generating the data. The Data Portal uses UK Secure eResearch Platform infrastructure to provide three core utilities: data discovery, access, and analysis. These are delivered using a 7 layered architecture comprising: data ingestion, data curation, platform interoperability, data discovery, access brokerage, data analysis and knowledge preservation. Automated, streamlined, and standardised procedures reduce the administrative burden for all stakeholders, particularly for requests involving multiple independent datasets, where a single request may be forwarded to multiple data controllers. Researchers are provided with their own secure 'lab' using VMware which is accessed using two factor authentication. Over the last 2 years, 160 project proposals involving 579 individual cohort data access requests were received. These were received from 268 applicants spanning 72 institutions (56 academic, 13 commercial, 3 government) in 16 countries with 84 requests involving multiple cohorts. Projects are varied including multi-modal, machine learning, and Mendelian randomisation analyses. Data access is usually free at point of use although a small number of cohorts require a data access fee.
International audience ; The Dementias Platform UK Data Portal is a data repository facilitating access to data for 3 370 929 individuals in 42 cohorts. The Data Portal is an end-to-end data management solution providing a secure, fully auditable, remote access environment for the analysis of cohort data. All projects utilising the data are by default collaborations with the cohort research teams generating the data. The Data Portal uses UK Secure eResearch Platform infrastructure to provide three core utilities: data discovery, access, and analysis. These are delivered using a 7 layered architecture comprising: data ingestion, data curation, platform interoperability, data discovery, access brokerage, data analysis and knowledge preservation. Automated, streamlined, and standardised procedures reduce the administrative burden for all stakeholders, particularly for requests involving multiple independent datasets, where a single request may be forwarded to multiple data controllers. Researchers are provided with their own secure 'lab' using VMware which is accessed using two factor authentication. Over the last 2 years, 160 project proposals involving 579 individual cohort data access requests were received. These were received from 268 applicants spanning 72 institutions (56 academic, 13 commercial, 3 government) in 16 countries with 84 requests involving multiple cohorts. Projects are varied including multi-modal, machine learning, and Mendelian randomisation analyses. Data access is usually free at point of use although a small number of cohorts require a data access fee.
The Dementias Platform UK Data Portal is a data repository facilitating access to data for 3 370 929 individuals in 42 cohorts. The Data Portal is an end-to-end data management solution providing a secure, fully auditable, remote access environment for the analysis of cohort data. All projects utilising the data are by default collaborations with the cohort research teams generating the data. The Data Portal uses UK Secure eResearch Platform infrastructure to provide three core utilities: data discovery, access, and analysis. These are delivered using a 7 layered architecture comprising: data ingestion, data curation, platform interoperability, data discovery, access brokerage, data analysis and knowledge preservation. Automated, streamlined, and standardised procedures reduce the administrative burden for all stakeholders, particularly for requests involving multiple independent datasets, where a single request may be forwarded to multiple data controllers. Researchers are provided with their own secure 'lab' using VMware which is accessed using two factor authentication. Over the last 2 years, 160 project proposals involving 579 individual cohort data access requests were received. These were received from 268 applicants spanning 72 institutions (56 academic, 13 commercial, 3 government) in 16 countries with 84 requests involving multiple cohorts. Projects are varied including multi-modal, machine learning, and Mendelian randomisation analyses. Data access is usually free at point of use although a small number of cohorts require a data access fee.
FMSR (Austria) ; FNRS (Belgium) ; FWO (Belgium) ; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) ; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) ; Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) ; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; MES (Bulgaria) ; CERN (China) ; CAS (China) ; MoST (China) ; NSFC (China) ; COLCIENCIAS (Colombia) ; MSES (Croatia) ; RPF (Cyprus) ; Academy of Sciences and NICPB (Estonia) ; Academy of Finland, ME, and HIP (Finland) ; CEA (France) ; CNRS/IN2P3 (France) ; BMBF (Germany) ; DFG (Germany) ; HGF (Germany) ; GSRT (Greece) ; OTKA (Hungary) ; NKTH (Hungary) ; DAE (India) ; DST (India) ; IPM (Iran) ; SFI (Ireland) ; INFN (Italy) ; NRF (Korea) ; LAS (Lithuania) ; CINVESTAV (Mexico) ; CONACYT (Mexico) ; SEP (Mexico) ; UASLP-FAI (Mexico) ; PAEC (Pakistan) ; SCSR (Poland) ; FCT (Portugal) ; JINR (Armenia, Belarus, Georgia, Ukraine, Uzbekistan) ; MST (Russia) ; MAE (Russia) ; MSTDS (Serbia) ; MICINN ; CPAN (Spain) ; Swiss Funding Agencies (Switzerland) ; NSC (Taipei) ; TUBITAK ; TAEK (Turkey) ; STFC (United Kingdom) ; DOE (USA) ; NSF (USA) ; European Union ; Leventis Foundation ; A. P. Sloan Foundation ; Alexander von Humboldt Foundation ; Measurements of inclusive charged-hadron transverse-momentum and pseudorapidity distributions are presented for proton-proton collisions at root s = 0.9 and 2.36 TeV. The data were collected with the CMS detector during the LHC commissioning in December 2009. For non-single-diffractive interactions, the average charged-hadron transverse momentum is measured to be 0.46 +/- 0.01 (stat.) +/- 0.01 (syst.) GeV/c at 0.9 TeV and 0.50 +/- 0.01 (stat.) +/- 0.01 (syst.) GeV/c at 2.36 TeV, for pseudorapidities between -2.4 and +2.4. At these energies, the measured pseudorapidity densities in the central region, dN(ch)/d eta vertical bar(vertical bar eta vertical bar and pp collisions. The results at 2.36 TeV represent the highest-energy measurements at a particle collider to date.
Austrian Federal Ministry of Education, Science and Research ; Austrian Science Fund ; Belgian Fonds de la Recherche Scientifique ; Fonds voor Wetenschappelijk Onderzoek ; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) ; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) ; Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) ; FAPERGS ; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; Bulgarian Ministry of Education and Science ; CERN ; Chinese Academy of Sciences ; Ministry of Science and Technology ; National Natural Science Foundation of China ; Colombian Funding Agency (COLCIENCIAS) ; Croatian Ministry of Science, Education and Sport ; Croatian Science Foundation ; Research Promotion Foundation, Cyprus ; Secretariat for Higher Education, Science, Technology and Innovation, Ecuador ; Ministry of Education and Research, Estonia ; Estonian Research Council, Estonia ; European Regional Development Fund, Estonia ; Academy of Finland ; Finnish Ministry of Education and Culture ; Helsinki Institute of Physics ; Institut National de Physique Nucleaire et de Physique des Particules / CNRS, France ; Commissariat a l'Energie Atomique et aux Energies Alternatives / CEA, France ; Bundesministerium fur Bildung und Forschung, Germany ; Deutsche Forschungsgemeinschaft, Germany ; Helmholtz-Gemeinschaft Deutscher Forschungszentren, Germany ; General Secretariat for Research and Technology, Greece ; National Research, Development and Innovation Fund, Hungary ; Department of Atomic Energy, India ; Department of Science and Technology, India ; Institute for Studies in Theoretical Physics and Mathematics, Iran ; Science Foundation, Ireland ; Istituto Nazionale di Fisica Nucleare, Italy ; Ministry of Science, ICT and Future Planning, Republic of Korea ; National Research Foundation (NRF), Republic of Korea ; Ministry of Education and Science of the Republic of Latvia ; Lithuanian Academy of Sciences ; Ministry of Education ; University of Malaya (Malaysia) ; Ministry of Science of Montenegro ; BUAP ; CINVESTAV ; CONACYT ; LNS ; SEP ; UASLP-FAI ; Ministry of Business, Innovation and Employment, New Zealand ; Pakistan Atomic Energy Commission ; Ministry of Science and Higher Education, Poland ; National Science Center, Poland ; Fundacao para a Ciencia e a Tecnologia, Portugal ; JINR, Dubna ; Ministry of Education and Science of the Russian Federation ; Federal Agency of Atomic Energy of the Russian Federation ; Russian Academy of Sciences ; Russian Foundation for Basic Research ; National Research Center Kurchatov Institute ; Ministry of Education, Science and Technological Development of Serbia ; Secretaria de Estado de Investigacion, Desarrollo e Innovacion, Programa Consolider-Ingenio 2010, Plan Estatal de Investigacion Cientifica y Tecnica y de Innovacion 2013-2016, Plan de Ciencia, Tecnologia e Innovacion 2013-2017 del Principado de Asturias, S ; Fondo Europeo de Desarrollo Regional, Spain ; Ministry of Science, Technology and Research, Sri Lanka ; ETH Board ; PSI ; SNF ; UniZH ; Canton Zurich ; SER ; Ministry of Science and Technology, Taipei ; Thailand Center of Excellence in Physics ; Institute for the Promotion of Teaching Science and Technology of Thailand ; Special Task Force for Activating Research ; National Science and Technology Development Agency of Thailand ; Scientific and Technical Research Council of Turkey ; Turkish Atomic Energy Authority ; National Academy of Sciences of Ukraine, Ukraine ; State Fund for Fundamental Researches, Ukraine ; Science and Technology Facilities Council, U.K. ; US Department of Energy ; US National Science Foundation ; Marie-Curie program (European Union) ; European Research Council (European Union) ; Horizon 2020 (European Union) ; Leventis Foundation ; A. P. Sloan Foundation ; Alexander von Humboldt Foundation ; Belgian Federal Science Policy Office ; Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium) ; Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium) ; F.R.S.-FNRS (Belgium) ; FWO (Belgium) ; Ministry of Education, Youth and Sports (MEYS) of the Czech Republic ; Hungarian Academy of Sciences (Hungary) ; New National Excellence Program UNKP (Hungary) ; NKFIA (Hungary) ; Council of Scientific and Industrial Research, India ; HOMING PLUS program of the Foundation for Polish Science ; European Union, Regional Development Fund ; Mobility Plus program of the Ministry of Science and Higher Education ; National Science Center (Poland) ; National Priorities Research Program by Qatar National Research Fund ; Programa de Excelencia Maria de Maeztu ; Programa Severo Ochoa del Principado de Asturias ; Thalis program ; Aristeia program ; EU-ESF ; Greek NSRF ; Rachadapisek Sompot Fund for Postdoctoral Fellowship, Chulalongkorn University (Thailand) ; Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand) ; Welch Foundation ; Weston Havens Foundation (U.S.A.) ; Estonian Research Council, Estonia: IUT23-4 ; Estonian Research Council, Estonia: IUT23-6 ; Horizon 2020 (European Union): 675440 ; FWO (Belgium): 30820817 ; NKFIA (Hungary): 123842 ; NKFIA (Hungary): 123959 ; NKFIA (Hungary): 124845 ; NKFIA (Hungary): 124850 ; NKFIA (Hungary): 125105 ; National Science Center (Poland): Harmonia 2014/14/M/ST2/00428 ; National Science Center (Poland): Opus 2014/13/B/ST2/02543 ; National Science Center (Poland): 2014/15/B/ST2/03998 ; National Science Center (Poland): 2015/19/B/ST2/02861 ; National Science Center (Poland): Sonata-bis 2012/07/E/ST2/01406 ; Welch Foundation: C-1845 ; An embedding technique is presented to estimate standard model tau tau backgrounds from data with minimal simulation input. In the data, the muons are removed from reconstructed mu mu events and replaced with simulated tau leptons with the same kinematic properties. In this way, a set of hybrid events is obtained that does not rely on simulation except for the decay of the tau leptons. The challenges in describing the underlying event or the production of associated jets in the simulation are avoided. The technique described in this paper was developed for CMS. Its validation and the inherent uncertainties are also discussed. The demonstration of the performance of the technique is based on a sample of proton-proton collisions collected by CMS in 2017 at root s = 13 TeV corresponding to an integrated luminosity of 41.5 fb(-1).
Austrian Federal Ministry of Science, Research and Economy ; Austrian Science Fund ; Belgian Fonds de la Recherche Scientifique ; Fonds voor Wetenschappelijk Onderzoek ; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) ; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) ; Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) ; Brazilian Funding Agency (FAPERGS) ; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; Bulgarian Ministry of Education and Science ; CERN ; Chinese Academy of Sciences, Ministry of Science and Technology ; National Natural Science Foundation of China ; Colombian Funding Agency (COLCIENCIAS ; Croatian Ministry of Science, Education and Sport ; Croatian Science Foundation ; Research Promotion Foundation, Cyprus ; Secretariat for Higher Education, Science, Technology and Innovation, Ecuador ; Ministry of Education and Research, Estonia ; Estonian Research Council, Estonia ; European Regional Development Fund, Estonia ; Academy of Finland ; Finnish Ministry of Education and Culture ; Helsinki Institute of Physics ; Institut National de Physique Nucleaire et de Physique des Particules/CNRS, France ; Commissariat a l'Energie Atomique et aux Energies Alternatives/CEA, France ; Bundesministerium fur Bildung und Forschung, Germany ; Deutsche Forschungsgemeinschaft, Germany ; Helmholtz-Gemeinschaft Deutscher Forschungszentren, Germany ; General Secretariat for Research and Technology, Greece ; National Research, Development and Innovation Fund, Hungary ; Department of Atomic Energy, India ; Department of Science and Technology, India ; Institute for Studies in Theoretical Physics and Mathematics, Iran ; Science Foundation, Ireland ; Istituto Nazionale di Fisica Nucleare, Italy ; Ministry of Science, ICT and Future Planning, Republic of Korea ; National Research Foundation (NRF), Republic of Korea ; Lithuanian Academy of Sciences ; Ministry of Education (Malaysia) ; University of Malaya (Malaysia) ; Ministry of Science of Montenegro ; Mexican Funding Agency (BUAP) ; Mexican Funding Agency (CINVESTAV) ; Mexican Funding Agency (CONACYT) ; Mexican Funding Agency (LNS) ; Mexican Funding Agency (SEP) ; Mexican Funding Agency (UASLP-FAI) ; Ministry of Business, Innovation and Employment, New Zealand ; Pakistan Atomic Energy Commission ; Ministry of Science and Higher Education, Poland ; National Science Center, Poland ; Fundacao para a Ciencia e a Tecnologia, Portugal ; JINR, Dubna ; Ministry of Education and Science of the Russian Federation ; Federal Agency of Atomic Energy of the Russian Federation ; Russian Academy of Sciences ; Russian Foundation for Basic Research ; National Research Center Kurchatov Institute ; Ministry of Education, Science and Technological Development of Serbia ; Secretaria de Estado de Investigacion, Desarrollo e Innovacion, Programa Consolider-Ingenio 2010, Spain ; Plan Estatal de Investigacion Cientifica y Tecnica y de Innovacion 2013-2016, Spain ; Plan de Ciencia, Tecnologia e Innovacion 2013-2017 del Principado de Asturias, Spain ; Fondo Europeo de Desarrollo Regional, Spain ; Ministry of Science, Technology and Research, Sri Lanka ; Swiss Funding Agency (ETH Board) ; Swiss Funding Agency (ETH Zurich) ; Swiss Funding Agency (PSI) ; Swiss Funding Agency (SNF) ; Swiss Funding Agency (UniZH) ; Swiss Funding Agency (Canton Zurich) ; Swiss Funding Agency (SER) ; Ministry of Science and Technology, Taipei ; Thailand Center of Excellence in Physics ; Institute for the Promotion of Teaching Science and Technology of Thailand ; Special Task Force for Activating Research ; National Science and Technology Development Agency of Thailand ; Scientific and Technical Research Council of Turkey ; Turkish Atomic Energy Authority ; National Academy of Sciences of Ukraine, Ukraine ; State Fund for Fundamental Researches, Ukraine ; Science and Technology Facilities Council, U.K. ; U.S. Department of Energy ; U.S. National Science Foundation ; Marie-Curie program (European Union) ; European Research Council and Horizon 2020 Grant (European Union) ; Leventis Foundation ; A. P. Sloan Foundation ; Alexander von Humboldt Foundation ; Belgian Federal Science Policy Office ; Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium) ; F.R.S.-FNRS (Belgium) under the Excellence of Science - EOS - be.h project ; FWO (Belgium) under the Excellence of Science - EOS - be.h project ; Ministry of Education, Youth and Sports (MEYS) of the Czech Republic ; Lendulet (Momentum) Program (Hungary) ; Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences (Hungary) ; New National Excellence Program UNKP (Hungary) ; NKFIA (Hungary) ; Council of Scientific and Industrial Research, India ; HOMING PLUS program of the Foundation for Polish Science ; European Union, Regional Development Fund (Poland) ; Mobility Plus program of the Ministry of Science and Higher Education (Poland) ; National Science Center (Poland) ; National Priorities Research Program by Qatar National Research Fund ; Programa de Excelencia Maria de Maeztu ; Programa Severo Ochoa del Principado de Asturias ; Thalis program - EU-ESF ; Aristeia program - EU-ESF ; Greek NSRF ; Rachadapisek Sompot Fund for Postdoctoral Fellowship, Chulalongkorn University (Thailand) ; Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand) ; Welch Foundation ; Weston Havens Foundation (U.S.A.) ; Estonian Research Council, Estonia: IUT23-4 ; Estonian Research Council, Estonia: IUT23-6 ; European Research Council and Horizon 2020 Grant (European Union): 675440 ; F.R.S.-FNRS (Belgium) under the Excellence of Science - EOS - be.h project: 30820817 ; FWO (Belgium) under the Excellence of Science - EOS - be.h project: 30820817 ; NKFIA (Hungary): 123842 ; NKFIA (Hungary): 123959 ; NKFIA (Hungary): 124845 ; NKFIA (Hungary): 124850 ; NKFIA (Hungary): 125105 ; European Union, Regional Development Fund (Poland): Harmonia 2014/14/M/ST2/00428 ; European Union, Regional Development Fund (Poland): Opus 2014/13/B/ST2/02543 ; European Union, Regional Development Fund (Poland): 2014/15/B/ST2/03998 ; European Union, Regional Development Fund (Poland): 2015/19/B/ST2/02861 ; European Union, Regional Development Fund (Poland): Sonata-bis 2012/07/E/ST2/01406 ; Mobility Plus program of the Ministry of Science and Higher Education (Poland): Harmonia 2014/14/M/ST2/00428 ; Mobility Plus program of the Ministry of Science and Higher Education (Poland): Opus 2014/13/B/ST2/02543 ; Mobility Plus program of the Ministry of Science and Higher Education (Poland): 2014/15/B/ST2/03998 ; Mobility Plus program of the Ministry of Science and Higher Education (Poland): 2015/19/B/ST2/02861 ; Mobility Plus program of the Ministry of Science and Higher Education (Poland): Sonata-bis 2012/07/E/ST2/01406 ; National Science Center (Poland): Harmonia 2014/14/M/ST2/00428 ; National Science Center (Poland): Opus 2014/13/B/ST2/02543 ; National Science Center (Poland): 2014/15/B/ST2/03998 ; National Science Center (Poland): 2015/19/B/ST2/02861 ; National Science Center (Poland): Sonata-bis 2012/07/E/ST2/01406 ; Welch Foundation: C-1845 ; A search is performed for a heavy Majorana neutrino (N), produced in leptonic decay of a W boson propagator and decaying into a W boson and a lepton, with the CMS detector at the LHC. The signature used in this search consists of two same-sign leptons, in any flavor combination of electrons and muons, and at least one jet. The data were collected during 2016 in proton-proton collisions at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 35.9 fb(-1). The results are found to be consistent with the expected standard model background. Upper limits are set in the mass range between 20 and 1600 GeV in the context of a Type-I seesaw mechanism, on |V-eN|(2), |V-N|(2), and |VeNV *|(2)/(|V-eN|(2)+|V-N|(2)), where V-N is the matrix element describing the mixing of N with the standard model neutrino of flavor = e, . For N masses between 20 and 1600 GeV, the upper limits on |V-N|(2) range between 2.3 x 10(-5) and unity. These are the most restrictive direct limits for heavy Majorana neutrino masses above 430 GeV.
BMWFW (Austria) ; FWF (Austria) ; FNRS (Belgium) ; FWO (Belgium) ; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) ; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) ; Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) ; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; MES (Bulgaria) ; CERN (China) ; CAS (China) ; MOST (China) ; NSFC (China) ; COLCIEN-CIAS (Colombia) ; MSES (Croatia) ; CSF (Croatia) ; RPF (Cyprus) ; SENESCYT (Ecuador) ; MoER (Estonia) ; ERC IUT (Estonia) ; ERDF (Estonia) ; Academy of Finland (Finland) ; MEC (Finland) ; HIP (Finland) ; CEA (France) ; CNRS/IN2P3 (France) ; BMBF (Germany) ; DFG (Germany) ; HGF (Germany) ; GSRT (Greece) ; NKFIA (Hungary) ; DAE (India) ; DST (India) ; IPM (Iran) ; SFI (Ireland) ; INFN (Italy) ; MSIP (Republic of Korea) ; NRF (Republic of Korea) ; LAS (Lithuania) ; MOE (Malaysia) ; UM (Malaysia) ; BUAP (Mexico) ; CINVESTAV (Mexico) ; CONACYT (Mexico) ; LNS (Mexico) ; SEP (Mexico) ; UASLP-FAI (Mexico) ; MBIE (New Zealand) ; PAEC (Pakistan) ; MSHE (Poland) ; NSC (Poland) ; FCT (Portugal) ; JINR (Dubna) ; MON (Russia) ; ROSATOM (Russia) ; RAS (Russia) ; RFBR (Russia) ; MESTD (Serbia) ; SEIDI (Spain) ; CPAN (Spain) ; PCTI (Spain) ; FEDER (Spain) ; Swiss Funding Agencies (Switzerland) ; MST (Taipei) ; ThEPCenter (Thailand) ; IPST (Thailand) ; STAR (Thailand) ; NSTDA (Thailand) ; TUBITAK (Turkey) ; TAEK (Turkey) ; NASU (Ukraine) ; SFFR (Ukraine) ; STFC (United Kingdom) ; DOE (USA) ; NSF (USA) ; Marie-Curie program (European Union) ; European Research Council (European Union) ; Horizon 2020 Grant (European Union) ; Leventis Foundation (FRIA-Belgium) ; Alfred P. Sloan Foundation (Belgium) ; Alexander von Humboldt Foundation (Belgium) ; Belgian Federal Science Policy Office (Belgium) ; Fonds pour la Formation a la Recherche dans l'Industrie et dans l'Agriculture (FRIA-Belgium) ; Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium) ; F.R.S.-FNRS (Belgium) ; FVVO (Belgium) under the Excellence of Science - EOS - be.h project ; Ministry of Education, Youth and Sports (MEYS) of the Czech Republic (Hungary) ; Lendtilet (Momentum) Program (Hungary) ; Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences (Hungary) ; New National Excellence Program UNKP (Hungary) ; Council of Science and Industrial Research, India ; HOMING PLUS program of the Foundation for Polish Science ; European Union, Regional Development Fund ; Mobility Plus program of the Ministry of Science and Higher Education ; National Science Centre (Poland) ; National Priorities Research Program by Qatar National Research Fund ; Programa Estatal de Fomento de la Investigation Cientifica y Tecnica de Excelencia Maria de Maeztu ; Programa Severo Ochoa del Principado de Asturias ; Thalis program - EU-ESF ; Aristeia program - EU-ESF ; Greek NSRF ; Rachadapisek Sompot Fund for Postdoctoral Fellowship, Chulalongkorn University (Thailand) ; Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand) ; Welch Foundation (USA) ; Weston Havens Foundation (USA) ; Sonata-bis ; Horizon 2020 Grant (European Union): 675440 ; FVVO (Belgium) under the Excellence of Science - EOS - be.h project: 30820817 ; NKFIA (Hungary): 123842 ; NKFIA (Hungary): 123959 ; NKFIA (Hungary): 124845 ; NKFIA (Hungary): 124850 ; NKFIA (Hungary): 125105 ; National Science Centre (Poland): Harmonia 2014/14/M/ST2/00428 ; National Science Centre (Poland): Opus 2014/13/B/ST2/02543 ; National Science Centre (Poland): 2014/15/B/ST2/03998 ; National Science Centre (Poland): 2015/19/B/ST2/02861 ; Programa Estatal de Fomento de la Investigation Cientifica y Tecnica de Excelencia Maria de Maeztu: MDM-2015-0509 ; Welch Foundation (USA): C-1845 ; Sonata-bis: 2012/07/E/ST2/01406 ; This Letter reports measurements of differential cross sections for the production of two Z bosons in association with jets in proton-proton collisions at root s = 8 and 13 TeV. The analysis is based on data samples collected at the LHC with the CMS detector, corresponding to integrated luminosities of 19.7 and 35.9 fb(-1) at 8 and 13 TeV, respectively. The measurements are performed in the leptonic decay modes ZZ -> l(+)l(-)l'(+)l'(-), where, l, l' = e, mu The differential cross sections as a function of the jet multiplicity, the transverse momentum p(T), and pseudorapidity of the P-T-leading and subleading jets are presented. In addition, the differential cross sections as a function of variables sensitive to the vector boson scattering, such as the invariant mass of the two P-T-leading jets and their pseudorapidity separation, are reported. The results are compared to theoretical predictions and found in good agreement within the theoretical and experimental uncertainties. (C) 2018 The Author(s). Published by Elsevier B.V.