Suchergebnisse

With ageing populations, rising incomes and a growing recognition of the link between diet and health, consumers are interested in new food products, supplements and ingredients with purported health benefits. The food industry has responded with new food innovations, formulations and enhancements that comprise the growing health food market, manifesting the need to design regulatory frameworks to govern valid health claims

Not uploaded.Key words: Estrogen Receptor; Progesterone Receptor; Breast Cancer and ImunohistochemistryDOI: 10.3126/jnhrc.v5i2.2468Journal of Nepal Health Research Council (JNHRC) Vol. 5, No.2, October 2007 26-32

Background: Fine Needle Aspiration Cytology (FNAC) is a reliable and least expensive method suitable for developing countries like Nepal for the investigation of lymphadenopathy. Knowledge about the pattern of lymphadenopathy is useful in pathological reporting as well as in many clinical settings with diagnostic dilemma. This is a baseline study to investigate the pattern of cervical lymphadenopathy by lymph node FNAC in Nepalese population. Methods: A retrospective study was conducted by critically analyzing the case reports on cervical lymph node FNAC from three years' records (July 2005 to June 2008) at the National Public Health Laboratory, Teku, Kathmandu. Review of all cytological reports were done according to standard guidelines and the diagnosis was classified and correlated with patients' age and ethnicity to explore the pattern and association. Results: Of 508 cervical lymph node FNAC cases, 50.4% was reactive non-specific, 22.4% was tubercular, 4.8 % malignant, 10% chronic granulomatous and the remaining was acute suppurative (12.4%). Highest incidence of malignancy was seen in the fifth decade (50%). Whereas, tubercular lymphadenopathy was found with increasing frequency through childhood (10.5%) and adolescence (21.7%) to young adulthood (30.4%), probably indicative of waning immunity of BCG vaccination. Ethnic groups comprising of Tamang, Sherpa and Bhote had the highest incidence of malignant as well as tubercular lymphadenopathy. Conclusion: The relationship of malignant and tubercular lymphadenopthy with age and ethnicity deserves further study. Efforts at preventing tubercular and early diagnosing malignant lymphadenopathy and reducing morbidity in general will find great usefulness in such associations. Key words: Cervical Lymphadenopathy, Fine Needle Aspiration Cytology, Pattern DOI: 10.3126/jnhrc.v7i1.2267 Journal of Nepal Health Research Council Vol. 7, No. 1, 2009 April 1-5

A 37 years old woman presented with a palpable mass in outer upper quadrant of the right breast. Excision biopsy showed Glycogen rich clear cell carcinoma (GRCCC) based on histological, PAS staining and immunohistochemical staining findings Histologically, most of tumor cells were clear cell type with variable intracytopasmic PAS positivity Immunohistochemically, the tumor was positive for progesterone receptor and vimention and foceally positive for cytokeratin and negative for estrogen receptor and S100. The patient underwent right quadrantectomy with right axillary clearance. This case was in stage IIa (T2N0Mx) and Elston and Ellis histological grade 2(Scores 3+2+1=6). GRCCC is a rare variant of breast carcinoma, with incidence calculated to be 1.4 to 3% and reports indicated a poorer prognosis for patient with GRCCC than those with usual breast cancer. Key words: Breast; Cancer glycogen rich clear cell carcinomadoi: 10.3126/jnhrc.v6i2.2218Journal of Nepal Health Research Council Vol. 6, No. 2, 2008 Page: 117-119

Background: Rubella is a viral infection. Congenital rubella syndrome is the most serious consequences of rubella which has been observed in pregnant women. This study has been done to reveal the association of rubella infection in women. Methods: The serum specimens were collected from women during their regular antenatal check up, in, was included in the study. Specimens were tested at NPHL every week following standard operating protocol of NPHL utilizing Human ELISA (German) kits and reagents. The results of the tests along with the clinical histories collected from the patient on a proforma file carried by the patients were analyzed following standard statistical tools. Results: During the three years study period, 320 serum samples were collected in 2006, 372 in 2007 and 400 in 2008, out of which 38 (11.87%), 72 (19.35%) and 49 (12.25%) of the women visiting NPHL during their antenatal checkup were found positive to anti-rubella IgM antibody respectively, indicating recent infection. Almost above 80% of the positive cases were from age group 20-30 years. Conclusions: The study showed the significant association of recent rubella infection in women which emphasizes requirement of adolescent or adult immunization with rubella vaccine at the earliest. Key words: anti-rubella IgM; congenital rubella syndrome; pregnant women; rubella. DOI: 10.3126/jnhrc.v7i2.3010 Journal of Nepal Health Research Council Vol.7(2) Apr 2009 76-79

Not uploaded.Key words: Urinary tract infection; Multidrug-resistanceDOI: 10.3126/jnhrc.v5i2.2471Journal of Nepal Health Research Council (JNHRC) Vol. 5, No.2, October 2007 49-54

Not uploaded.Key words: TORCH infection; Serum; IgM; ELISADOI: 10.3126/jnhrc.v5i2.2467Journal of Nepal Health Research Council (JNHRC) Vol. 5, No.2, October 2007 21-25