Suchergebnisse

AbstractIn 1996, the Water Environment Federation of the USA, the European Water Pollution Control Association (now the European Water Association), and the International Association of Water Quality (now the International Water Association) produced a Global Atlas of Waste‐water Sludge and Biosolids Use and Disposal. Various ideas have been proposed to interpret the comparisons of international practices; from these, propositions have been derived for policies on sustainable management which, in the UK, would (a) comply with the recent agreement between the water industry and food retailers, and (b) not reach soil metal limits in less than fifty years. Comparisons are made between Europe and the USA, and the differences are found to be less than were previously assumed. However, changes are imminent, which might alter this situation.

ABSTRACTThe paper attempts to review current and future practices in the UK against a European background.Sludge disposal has become a subject which is developing rapidly again and, since the presentation of this paper, there have been a number of developments, e.g. the adoption by the EC of its hazardous waste Directive in December 1991. Untreated sludge or sludge which is unsuitable for use in agriculture will be classified as a hazardous waste, subject to certain criteria. This makes the work on sludge classification even more crucial.

Current shortages of hepatitis B virus (HBV) vaccine have created recent media interest, including representation in the BMJ (1). HBV deserves to make headlines; an estimated 250 million individuals are chronically infected and there has been neglect of funding, political advocacy, research and clinical services. International Sustainable Development Goals for viral hepatitis aspire towards 'elimination as a public health threat' by 2030 (2). Vaccination is a crucial component of the multi-pronged effort that will be required to meet these targets.

The question of how to make academic research more useful to government, and frustration over its lack of obvious use, have long been the subject of policy makers' and scholars' attention. These have driven the global development of institutionalised links between the two communities, while also leading to a broad consensus as to why the goal is often not realised. In order to better explain the barriers, this paper takes the concept of "translation" very literally, and proposes an innovative approach, which analyses academic and policy practices using ideas from the humanities-based discipline of Translation Studies. This enables an exploration of what constitutes good translation, and in particular of the tension between keeping faith with the original material and users' understandable emphasis on functionality. The conclusion is that while some aspect of original research content must be maintained, what this is cannot be prescribed: the appropriate equivalence between original and translation is always context-dependent. This throws the emphasis on the relational aspects of translatorial action for promoting "good translation". The argument follows Christiane Nord in seeing the core issue as the moral one of a translator's loyalty to original author and user, and so also of mutual trust between academics and civil servants. This raises important questions about how such trust can be cultivated, and so finally leads to an emphasis on the importance of an endeavour shared by researchers and policy makers, which recognises and respects their different environments and the work involved in creating useful meaning from scholarly research.

As professionals concerned for people with dementia today and dedicated to finding more effective treatment and prevention for dementia tomorrow, we value our membership of the European Union (EU) and are deeply concerned by the prospect of the UK exiting. The EU has made dementia research a priority and has made substantial funds available for research that is driving faster, more effective clinical trials that are our best hope of finding a disease-modifying therapy. With its strong science and translational research base, the UK is making a considerable contribution to these studies.

International audience ; The Dementias Platform UK Data Portal is a data repository facilitating access to data for 3 370 929 individuals in 42 cohorts. The Data Portal is an end-to-end data management solution providing a secure, fully auditable, remote access environment for the analysis of cohort data. All projects utilising the data are by default collaborations with the cohort research teams generating the data. The Data Portal uses UK Secure eResearch Platform infrastructure to provide three core utilities: data discovery, access, and analysis. These are delivered using a 7 layered architecture comprising: data ingestion, data curation, platform interoperability, data discovery, access brokerage, data analysis and knowledge preservation. Automated, streamlined, and standardised procedures reduce the administrative burden for all stakeholders, particularly for requests involving multiple independent datasets, where a single request may be forwarded to multiple data controllers. Researchers are provided with their own secure 'lab' using VMware which is accessed using two factor authentication. Over the last 2 years, 160 project proposals involving 579 individual cohort data access requests were received. These were received from 268 applicants spanning 72 institutions (56 academic, 13 commercial, 3 government) in 16 countries with 84 requests involving multiple cohorts. Projects are varied including multi-modal, machine learning, and Mendelian randomisation analyses. Data access is usually free at point of use although a small number of cohorts require a data access fee.

International audience ; The Dementias Platform UK Data Portal is a data repository facilitating access to data for 3 370 929 individuals in 42 cohorts. The Data Portal is an end-to-end data management solution providing a secure, fully auditable, remote access environment for the analysis of cohort data. All projects utilising the data are by default collaborations with the cohort research teams generating the data. The Data Portal uses UK Secure eResearch Platform infrastructure to provide three core utilities: data discovery, access, and analysis. These are delivered using a 7 layered architecture comprising: data ingestion, data curation, platform interoperability, data discovery, access brokerage, data analysis and knowledge preservation. Automated, streamlined, and standardised procedures reduce the administrative burden for all stakeholders, particularly for requests involving multiple independent datasets, where a single request may be forwarded to multiple data controllers. Researchers are provided with their own secure 'lab' using VMware which is accessed using two factor authentication. Over the last 2 years, 160 project proposals involving 579 individual cohort data access requests were received. These were received from 268 applicants spanning 72 institutions (56 academic, 13 commercial, 3 government) in 16 countries with 84 requests involving multiple cohorts. Projects are varied including multi-modal, machine learning, and Mendelian randomisation analyses. Data access is usually free at point of use although a small number of cohorts require a data access fee.