Suchergebnisse

ABSTRACTThe Russian invasion of Ukraine has led to the imposition of economic sanctions intended to isolate Russia from much of global commerce, which implicitly includes the medical research enterprise. The prospect of ongoing isolation of Russia's substantial research enterprise raises issues related to but distinct from the more familiar problem of corruption. In this paper, we identify reasons that the culture of research ethics in Russia may have been weak even before the war, contributing to hard questions about its future role in the global clinical research community.

ABSTRACTIn the midst of the Covid‐19 pandemic, ethicists, researchers, and journalists have recommended studies that deliberately infect healthy volunteers with the coronavirus as a scientific means of expediting vaccine development. In this essay, we trace the history of infection challenge experiments and reflect on the Nuremberg Code of 1947, issued in response to brutal human experiments conducted by Nazi investigators in concentration camps. We argue that the Code continues to offer valuable guidance for assessing the ethics of this controversial form of research, with respect particularly to the acceptable limits to research risks and the social value of research necessary to justify exposing human participants to these risks.