Clinica delle organizzazioni: prospettive teoriche e pratiche tra Lacan, Deleuze e Foucault
In: Altro discorso 13
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In: Altro discorso 13
In: Environmental science and pollution research: ESPR, Band 25, Heft 29, S. 29295-29303
ISSN: 1614-7499
In the European Union (EU), where architectural heritage is significant, enhancing the energy performance of historical buildings is of great interest. Constraints such as the lack of space, especially within the historical centers and architectural peculiarities, make the application of technologies for renewable energy production and storage a challenging issue. This study presents a prototype system consisting of using the renewable energy from a photovoltaic (PV) array to compress air for a later expansion to produce electricity when needed. The PV-integrated small-scale compressed air energy storage system is designed to address the architectural constraints. It is located in the unoccupied basement of the building. An energy analysis was carried out for assessing the performance of the proposed system. The novelty of this study is to introduce experimental data of a CAES (compressed air energy storage) prototype that is suitable for dwelling applications as well as integration accounting for architectural constraints. The simulation, which was carried out for an average summer day, shows that the compression phase absorbs 32% of the PV energy excess in a vessel of 1.7 m(3), and the expansion phase covers 21.9% of the dwelling energy demand. The electrical efficiency of a daily cycle is equal to 11.6%. If air is compressed at 225 bar instead of 30 bar, 96.0% of PV energy excess is stored in a volume of 0.25 m3, with a production of 1.273 kWh, which is 26.0% of the demand.
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In: Waste management: international journal of integrated waste management, science and technology, Band 170, S. 75-81
ISSN: 1879-2456
In: Waste management: international journal of integrated waste management, science and technology, Band 73, S. 496-503
ISSN: 1879-2456
In: WM-23-375
SSRN
There is considerable interest recently in by-products for application in green buildings. These materials are widely used as building envelope insulators or blocks. In this study, an experimental study was conducted to test stranded driftwood residues as raw material for possible thermo-acoustic insulation panel and environmentally sustainable brick. The thermal and acoustic characteristics of such a natural by-product were examined. Part of samples were mineralized by means of cement-based additive to reinforce the material and enhance its durability as well as fire resistance. Several mixtures with different sizes of ground wood chips and different quantities of cement were investigated. The thermo-acoustic in-lab characterization was aimed at investigating the thermal conductivity, thermal diffusivity, volumetric specific heat, and acoustic transmission loss. All samples were tested before and after mineralization. Results from this study indicate that it is possible to use stranded driftwood residues as building materials with competitive thermo-acoustic properties. In fact, the thermal conductivity was shown to be always around 0.07 W/mK in the unbound samples, and around double that value for the mineralized samples, which present a much higher volumetric specific heat (1.6 MJ/m3K) and transmission loss capability. The lignin powder showed a sort of intermediate behavior between the unbound and the mineralized samples. ; The authors would like to thank Gabriele Franceschetti and CVR s.r.l. for assisting the mineralization procedure of the samples. Anna Laura Pisello's acknowledgments are due to the "CIRIAF program for UNESCO" in the framework of the UNESCO Chair "Water Resources Management and Culture", for supporting her research. The research was founded by the Italian Environmental Ministry with an agreement entitled "Recovery and energy valorization of stranded driftwood residues" in 2014–2016. The research team leading to these results has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No. 657466 (INPATH–TES) and No. 678407 (ZERO-PLUS).
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Abstract Scientific discoveries that provide strong evidence of antitumor effects in preclinical models often encounter significant delays before being tested in patients with cancer. While some of these delays have a scientific basis, others do not. We need to do better. Innovative strategies need to move into early stage clinical trials as quickly as it is safe, and if successful, these therapies should efficiently obtain regulatory approval and widespread clinical application. In late 2009 and 2010 the Society for Immunotherapy of Cancer (SITC), convened an "Immunotherapy Summit" with representatives from immunotherapy organizations representing Europe, Japan, China and North America to discuss collaborations to improve development and delivery of cancer immunotherapy. One of the concepts raised by SITC and defined as critical by all parties was the need to identify hurdles that impede effective translation of cancer immunotherapy. With consensus on these hurdles, international working groups could be developed to make recommendations vetted by the participating organizations. These recommendations could then be considered by regulatory bodies, governmental and private funding agencies, pharmaceutical companies and academic institutions to facilitate changes necessary to accelerate clinical translation of novel immune-based cancer therapies. The critical hurdles identified by representatives of the collaborating organizations, now organized as the World Immunotherapy Council, are presented and discussed in this report. Some of the identified hurdles impede all investigators; others hinder investigators only in certain regions or institutions or are more relevant to specific types of immunotherapy or first-in-humans studies. Each of these hurdles can significantly delay clinical translation of promising advances in immunotherapy yet if overcome, have the potential to improve outcomes of patients with cancer.
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