Realizada em Brasilia, de 30 de maio a 1 de junho de 2001, a VI Conferencia Nacional de Direitos Humanos trouxe como tema central "Cidadania: un instrumento contra a impunidade". As Conferencias Nacionais de Direitos Humanos vem configurando-se, desde 1996, como agendas importantes no cenario de posicionamento dos governos federais, estaduais e municipais no tema da garantia e promocao dos direitos humanos. O objetivo deste artigo e indicar elementos para o debate sobre alternativas de elaboracao e implementacao de politicas publicas baseadas nos direitos humanos, em especial nos municipios, a partir de uma breve abordagem sobre os avancos obtidos no tema nas conferencias mencionadas. (ram/DÜI)
O presente artigo aborda a inserção da mulher na política institucional do Rio Grande do Norte e sua história de pioneirismo. Busca investigar a representatividade das potiguares na política institucional do estado analisando o percurso histórico a partir das desigualdades entre os gêneros, tendo como base o método Materialista Histórico Dialético. Para o alcance desses objetivos, analisa documentos históricos disponibilizados na Assembleia Legislativa do Rio Grande do Norte e realiza entrevistas semiestruturadas com as parlamentares eleitas vereadoras pelo estado potiguar nas eleições de 2016, ano do golpe que destituiu a primeira mulher eleita Presidente do Brasil. O estudo concluiu que há uma relação dialética entre representatividade, políticas públicas e participação ativa, todavia não se faz suficiente para implicar a abertura concreta de mais espaço na política para mulheres, bem como a superação das relações desiguais que as subjugam.
Catharanthus roseus is a highly valuable medicinal plant producing several terpenoid indole alkaloids (TIAs) with pharmaceutical applications, including the anticancer agents vinblastine and vincristine. Due to the interest in its TIAs, C. roseus is one of the most extensively studied medicinal plants and has become a model species for the study of plant secondary metabolism. However, very little is known about the cytogenetics and genome size of this species, in spite of their importance for breeding programmes, TIA genetics and emerging genomic research. Therefore, the present paper provides a karyotype description and fluorescence in situ hybridization (FISH) data for C. roseus, as well as a rigorous characterization of its genome size. ; This work was funded by (i) Programa Operacional Ciência e Inovação (POCI 2010—financed by European Union and Fundação para a Ciência e Tecnologia from the Portuguese Government), (ii) three scholar/fellowships from Fundação para a Ciência e Tecnologia (SFRH/BM/566/2000 to G.G, SFRH/BPD/20669/2004 to P.D, and SFRH/BPD/48853/2008 to H.O), and (iii) a Scientific Mecenate award from Grupo Jerónimo Martins SA. ; published
A transição demográfica traz consigo inúmeras transformações na estrutura etária, sendo uma delas o envelhecimento populacional. No Brasil, estima-se que 22,6% da população terá 65 anos ou mais em 2050, cenário semelhante ao vivido atualmente pelos países desenvolvidos. Diante dessas mudanças, debatem-se os limites e potencialidades da migração como uma possível forma de amenização dessa situação. De um lado, os imigrantes podem integrar a população em idade ativa, constituindo uma parcela importante da mão-de-obra brasileira futura. Por outro lado, emerge a preocupação que o país seja capaz de absorver esses estrangeiros e que, mais tarde, esses também envelhecerão, aumentando o peso das idades mais envelhecidas. Nesse contexto, surge o termo "migração de reposição" que se refere ao processo migratório com intuito demográfico relativo à estrutura etária ou tamanho populacional. Dessa forma, para analisar o possível impacto da componente migratória sobre a estrutura etária brasileira até o ano de 2050, elaborou-se projeções demográficas a partir de distintos cenários com base no Método das Componentes Demográficas. Os cenários que objetivaram a atenuação da razão de dependência ou basearam-se em taxas líquidas de migração de países receptores de migrantes, como a Alemanha, foram os que resultaram em saldos migratórios mais razoáveis.
Abstract The concern to create cleaner and more ecosystem-friendly production processes has extended to the parking sector in Spain. Since the creation of the multi-level institutional framework for sustainable mobility management (mainly composed of the Infrastructure, Transport and Housing Plan 2012–2024, the Sustainable Urban Mobility Plans, Law 9/2006, and Law 9/2017), environmental considerations, including sustainable management certificates, have occupied a privileged place in public procedures for the management of parking structures and regulated surface parking facilities. Although there have been previous academic studies on the design and implementation of SUMPs and the growth of the parking sector, this article is novel in that it analyzes the market concentration of the parking sector in a scenario where climate change policies are crucial and the importance of sustainability certificates takes on a new meaning. Therefore, the objective of this article is to analyze whether the growing importance of environmental aspects has led to an increase in the concentration level of the parking sector in Spain. For this purpose, several concentration and stability indices are calculated. The results show that, although there are additional factors, the certification of a cleaner activity is relevant in the process of public tenders in the sector, which has served to strengthen the dominance of the most prominent companies in the sector that are in possession of environmental certificates. This shows that environmental policies can also have negative effects on the market, so the results of this analysis are of great value to policymakers.
This article belongs to the Special Issue Multifunctional Magnetic Nanocomposites: Innovative Processing and Applications. ; Magnetic nanoparticles (NP), such as magnetite, have been the subject of research for application in the biomedical field, especially in Magnetic Hyperthermia Therapy (MHT), a promising technique for cancer therapy. NP are often coated with different compounds such as natural or synthetic polymers to protect them from oxidation and enhance their colloidal electrostatic stability while maintaining their thermal efficiency. In this work, the synthesis and characterization of magnetite nanoparticles coated with fucoidan, a biopolymer with recognized biocompatibility and antitumoral activity, is reported. The potential application of NP in MHT was evaluated through the assessment of Specific Loss Power (SLP) under an electromagnetic field amplitude of 14.7 kA m−1 and at 276 kHz. For fucoidan-coated NP, it was obtained SLP values of 100 and 156 W/g, corresponding to an Intrinsic Loss Power (ILP) of 1.7 and 2.6 nHm2kg−1, respectively. These values are, in general, higher than the ones reported in the literature for non-coated magnetite NP or coated with other polymers. Furthermore, in vitro assays showed that fucoidan and fucoidan-coated NP are biocompatible. The particle size (between ca. 6 to 12 nm), heating efficiency, and biocompatibility of fucoidan-coated magnetite NP meet the required criteria for MHT application. ; This work was developed within the scope of the project CICECO-Aveiro Institute of Materials, UIDB/50011/2020 & UIDP/50011/2020, financed by national funds through the Portuguese Foundation for Science and Technology/MCTES. The work was also funded through FCT projects PTDC/NAN-MAT/28785/2017 (OrMagNa), UID/MULTI/04046/2019 (BioISI) and UIDP/50017/2020 & UIDB/50017/2020 (CESAM). This work was also funded by national funds (OE), through FCT—Fundação para a Ciência e a Tecnologia, I.P., in the scope of the framework contract foreseen in the numbers 4, 5 and 6 of the article 23, of the Decree-Law 57/2016, of August 29, changed by Law 57/2017, of July 19. The Portuguese Foundation for Science and Technology (FCT) is also acknowledged for the research contract under Stimulus of Scientific Employment of P. Ferreira (IF/00300/2015) and H. Oliveira (CEECIND/04050/2017), the Post-Doctoral grant of C. Nunes (SFRH/BPD/100627/2014), and the research contract of V. Bastos (CDL-CTTRI-161-ARH/2018) funded by the FCT project (POCI-01-0145-FEDER-031794). AM acknowledges the Spanish Ministry of Science (RYC2018-024561-I) and to the Natural National Science Foundation of China through the grants NSFC- 21850410448 & NSFC- 21835002. The authors acknowledge to The Centre for High-resolution Electron Microscopy (CħEM), supported by SPST of ShanghaiTech University under contract No. EM02161943. This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 823717—ESTEEM3. ; Peer reviewed
