Suchergebnisse

Arterial ageing is characterized by increasing arterial stiffness as measured by pulse wave velocity (PWV). This process is enhanced in participants with early vascular ageing (EVA), but slowed in participants with healthy vascular ageing (HVA). We aimed to describe characteristics of EVA and HVA in a transcontinental study including 11 cohorts. ; The Asklepios Study is supported by the Fund for Scientific Research – Flanders (FWO research grants G042703 and G083810N). The Rotterdam Study is supported by the Erasmus Medical Center and Erasmus University Rotterdam; the Netherlands Organization for Scientific Research; the Netherlands Organization for Health Research and Devel- opment (ZonMw); the Research Institute for Diseases in the Elderly (RIDE); the Netherlands Heart Foundation; the Ministry of Education, Culture and Science; the Ministry of Health Welfare and Sports; the European Commission; and the Municipality of Rotterdam. The SardiNIA team was supported by Contract NO1-AG- 1–2109 from the NIA. This research was supported in part by the Intramural Research Program of the NIH, National Institute on Aging (USA). The Baltimore Longitudinal Study of Aging (BLSA) is supported in part by the Intramural Research Program of the NIH, National Institute on Aging. The Kingmen Aging Study was supported, in part, by a grant from the National Science Council (NSC 99-2314-B- 010-034-MY3), an intramural grant from the Taipei Veterans General Hospital (grant V102C-119), Research and Devel- opment contract NO1-AG-1–2118, and the Intramural Research Program of the National Institute on Aging, National Institutes of Health. The Malmoe Diet Cancer – Cardiovascular Study was supported by grants from the Swedish Research Council (K2008-65X-20752-01-3, K2011-65X-20752-04-6), the Lund- stroms Foundation, the Swedish Heart-Lung Foundation (2010-0244; 2013-0249) and ALF government grants (Dnr: 2012/1789) ...

Digital ; The World Health Organization (WHO) Global Hearts Initiative offers technical packages to reduce the burden of cardiovascular diseases through population-wide and targeted health services interventions. The Pan American Health Organization (PAHO) has led implementation of the HEARTS in the Americas Initiative since 2016. The authors mapped the developmental stages, barriers, and facilitators to implemen-tation among the 371 primary health care centers in the participating 12 countries. The authors used the qualitative method of document review to examine cumula-tive country reports, technical meeting notes, and reports to regional stakeholders. Common implementation barriers include segmentation of health systems, overcom-ing health care professionals' scope of practice legal restrictions, and lack of health information systems limiting operational evaluation and quality improvement mecha-nisms. Main implementation facilitators include political support from ministries of health and leading scientific societies, PAHO's role as a regional catalyst to implemen-tation, stakeholder endorsement demonstrated by incorporating HEARTS into official documents, and having a health system oriented to primary health care. Key lessons include the need for political commitment and cultivating on-the-ground leadership to initiate a shift in hypertension care delivery, accompanied by specific progress in the development of standardized treatment protocols and a set of high-quality medicines. By systematizing an implementation strategy to ease integration of interventions into delivery processes, the program strengthened technical leadership and ensured sus-tainability. These study findings will aid the regional approach by providing a staged planning model that incorporates lessons learned. A systematic approach to imple-mentation will enhance equity, efficiency, scale-up, and sustainability, and ultimately improve population hypertension control. ; Ciencias Médicas y de la Salud