Suchergebnisse

Climate change has been a hotspot of scientific research in the world for decades, which caused serious effects of agriculture, water resources, ecosystem, environment, human health and so on. In China, drought accounts for almost 50 % of the total loss among all the meteorological disasters. In this article the interpolated and corrected precipitation of one GCM (HadGEM2-ES) output under four emission scenarios (RCP2.6, 4.5, 6.0, 8.5) were used to analyze the drought. The standardized precipitation index (SPI) calculated with these data was used to assess the climate change impact on droughts from meteorological perspectives. Based on five levels of SPI, an integrated index of drought hazard (IIDH) was established, which could explain the frequency and intensity of meteorological drought in different regions. According to yearbooks of different provinces, 15 factors have been chosen which could represent the impact of drought on human being, crops, water resources and economy. Exposure index, sensitivity index and adaptation index have been calculated in almost 2400 counties and vulnerability of drought has been evaluated. Based on hazard and vulnerability evaluation of drought, risk assessment of drought in China under the RCP2.6, 4.5, 6.0, 8.5 emission scenarios from 2016 to 2050 has been done. Results from such a comprehensive study over the whole country could be used not only to inform on potential impacts for specific sectors but also can be used to coordinate adaptation/mitigation strategies among different sectors/regions by the central government.

Given an existing stock allocation in an inventory system, it is often necessary to perform reallocation over multiple time points to address inventory imbalance and maximize availability. In this paper, we focus on the situation where there are two opportunities to perform reallocation within a replenishment cycle. We derive a mathematical model to determine when and how to perform reallocation. Furthermore, we consider the extension of this model to the situation allowing an arbitrary number of reallocations. Experimental results show that the two-reallocation approach achieves better performance compared with the single-reallocation approach found in the literature. We also illustrate how to apply the proposed model to design cost-optimal periodic resupply policies.

Context The ability of influenza A viruses to recognise and bind to cell surface receptors such as sialic acid linked to galactose by an α2,3 linkage (SAα2,3-gal) and sialic acid linked to galactose by an α2,6 linkage (SAα2,6-gal) is a major determinant of influenza A virus infection. Although the epidemiological surveys of influenza A virus infection in raptors suggest that some raptor species are susceptible to influenza A viruses under natural conditions, the sialic acid profiles in the respiratory and intestinal tracts of raptors are unknown. Aims To examine the sialic acid receptor profiles in the respiratory tracts of the selected raptor species and assess the potential susceptibility of raptors to avian and human influenza viruses and the role of raptors in the epidemiology and evolution of influenza A viruses. Methods The lectin immunohistochemistry staining method was used to examine the sialic acid profiles in the respiratory tracts of eight different species of raptors. Key results A strong staining with Maackia amurensis agglutinin (MAA), specific for sialic acid linked to galactose by an α2,3 linkage (SAα2,3-gal), was observed in the epithelial cells of the respiratory tract of Accipiter nisus and Falco tinnunculus. However, a positive staining for both MAA and Sambucus nigra agglutinin (SNA), specific for sialic acid linked to galactose by an α2,6 linkage (SAα2,6-gal), was detected in the epithelial cells of the upper respiratory tract of Accipiter gularis, Buteo buteo, Otus sunia, Bubo bubo and Asio otus, and in the epithelial cells of the alveoli of Buteo buteo, Falco peregrinus, Otus sunia and Bubo bubo. Conclusions Both avian and human influenza A virus receptors are expressed in six species of raptors examined. There are some variations in the type and distribution of sialic acid receptor expression among different raptor species. No correlation between phylogeny of birds and their sialic acid receptor distributions was observed. Implications Since SAα2,3-gal and SAα2,6-gal are often considered as the primary receptors for avian influenza A viruses and human influenza A viruses, respectively, our data suggest that raptors could be a potential host for avian and human influenza A viruses.