Suchergebnisse

In this paper, a one-stop e-Government solution will be proposed for the existing Korean government multi-ministry Employment-Welfare plus system that utilizes latest IT technologies. Since 2001, the Korean government had established 11 initiatives and 31 roadmaps to build e-Government infrastructure. Although this infrastructure has been very successful and well-esteemed in the international society, several improvements are required towards a one-stop shop solution. Currently, the system used by the Korean government is not a one-stop solution with a single point for the citizen to access government services. A Virtual Employment – Welfare Plus Centre (VEWPC) is then introduced to unify the services offered to the citizen. Comparing this VEWS with UK's e-Government solution and review of corresponding literature, several requirements for change towards a one-stop shop solution implementation have been identified. A refined architecture to implement a South Korean e-Government one-stop shop is identified and proposed in this paper. Future plans for the applicability and cost of its adoption are also identified.

Objective: To investigate the viscosity and wettability of hyaluronic acid (HA), its effects on lysozyme and peroxidase activities, and its candidacidal activity. Materials and methods: Human whole saliva, HA, hen egg-white lysozyme (HEWL), and bovine lactoperoxidase (bLPO) were used. Viscosity was measured with a cone-and-plate digital viscometer, while wettability was determined by measuring the contact angle. Lysozyme activity was determined by the turbidimetric method. Peroxidase activity was determined with NbsSCN assay. Candidacidal activity was determined by comparing colony forming units. Results: The viscosity of HA solutions was proportional to its concentration, with 0.05 mg ml-1 of HA in distilled water or 0.5 mg ml-1 in simulated salivary buffer displaying similar viscosity values to stimulated whole saliva. The contact angle of HA solutions showed no significant differences according to the tested materials and tested HA concentrations. Contact angles of HA solutions on acrylic resin were higher than those of human saliva. HA did not affect lysozyme or peroxidase activities of whole saliva as well as HEWL or bLPO activities. HA also showed no candidacidal activity. Conclusions: The viscoelastic properties of HA compared with human saliva were objectively confirmed, indicating a vital role for HA in the development of effective salivary substitutes. ; This work was supported by the Korea Science & Engineering Foundation (KOSEF) grant funded by Korea government (R13-2008-008-01001-0) through the Oromaxillofacial Dysfunction Research Center for the Elderly (ODRCE) at Seoul National University.