The Invention of the Scold
In: History workshop journal: HWJ, Band 66, Heft 1, S. 253-258
ISSN: 1477-4569
13 Ergebnisse
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In: History workshop journal: HWJ, Band 66, Heft 1, S. 253-258
ISSN: 1477-4569
In: Journal of social history, Band 30, Heft 2, S. 393-413
ISSN: 1527-1897
In: Wildlife Research, Band 11, Heft 1, S. 83
A systematic technique is described for the census of small arboreal mammals, by placing traps on
portable wooden brackets attached to trees in a grid formation. The technique, and some effects of trap
position and trapping season, was evaluated in a 24-ha patch of open forest near Armidale, N.S.W.
Trapping season and the species of tree supporting traps was found to influence the success of sugar
glider capture.
In: The journal of development studies: JDS, Band 34, Heft 4, S. 139-148
ISSN: 0022-0388
In: American behavioral scientist: ABS, Band 31, Heft May/Jun 88
ISSN: 0002-7642
In: The ANNALS of the American Academy of Political and Social Science, Band 580, Heft 1, S. 103-133
In: Alcohol and alcoholism: the international journal of the Medical Council on Alcoholism (MCA) and the journal of the European Society for Biomedical Research on Alcoholism (ESBRA), Band 31, Heft 6, S. 577-582
ISSN: 1464-3502
OBJECTIVE: To review the societal and economic implications of the use of genetic information to individualize drug therapies. Although studies have begun to address the ethical issues raised by the use of genetic information , few have examined the implications of pharmacogenomics f rom the perspective of health services research. PRINCIPAL FINDINGS: We propose a research agenda for health services research in three areas: (1) to evaluate the effectiveness and cost-effectiveness of pharmacogenomics; (2) to evaluate the effect of pharmacogenomics from the perspective of patients, providers, insurers, industry, and government ; and (3) to evaluate the ethical and societal implications of pharmacogenomics. Throughout the article we use the example of HIV genotyping as an illustration of how genetic technology is disseminated and used. CONCLUSION: More research is needed on the societal and economic implications of pharmacogenomics to inform the clinical and policy decisions about its use that will be increasingly urgent in the future.
BASE
In: Political psychology: journal of the International Society of Political Psychology, Band 20, Heft 2, S. 40-246
ISSN: 0162-895X
In: Teaching sociology: TS, Band 16, Heft 4, S. 455
ISSN: 1939-862X
Design parameters for microphysiological systems (MPS) are driven by the need for new tools to answer questions focusing on human physiology in a robust and reliable manner. Within this perspective, engineering benchmarks and principles are identified to guide the construction of new devices in the MPS field, with emphasis placed on the design principles common to all tissues, as well as those unique to a subset of tissues. Leading organ replica technologies that recapitulate various functions of the brain, heart, intestine, and lung are highlighted as examples that meet the identified benchmarks and standards, with current barriers for large scale production and commercialization discussed. To reach their full potential and achieve widespread use, MPS will have to be recognized officially by government agencies, and toward this end, considerations of MPS as a potential regulatory tool are presented.
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In: Rand Report, R-3564-A
World Affairs Online
Background: The COVID-19 pandemic has disrupted routine hospital services globally. This study estimated the total number of adult elective operations that would be cancelled worldwide during the 12 weeks of peak disruption due to COVID-19. Methods: A global expert response study was conducted to elicit projections for the proportion of elective surgery that would be cancelled or postponed during the 12 weeks of peak disruption. A Bayesian β-regression model was used to estimate 12-week cancellation rates for 190 countries. Elective surgical case-mix data, stratified by specialty and indication (surgery for cancer versus benign disease), were determined. This case mix was applied to country-level surgical volumes. The 12-week cancellation rates were then applied to these figures to calculate the total number of cancelled operations. Results: The best estimate was that 28 404 603 operations would be cancelled or postponed during the peak 12 weeks of disruption due to COVID-19 (2 367 050 operations per week). Most would be operations for benign disease (90·2 per cent, 25 638 922 of 28 404 603). The overall 12-week cancellation rate would be 72·3 per cent. Globally, 81·7 per cent of operations for benign conditions (25 638 922 of 31 378 062), 37·7 per cent of cancer operations (2 324 070 of 6 162 311) and 25·4 per cent of elective caesarean sections (441 611 of 1 735 483) would be cancelled or postponed. If countries increased their normal surgical volume by 20 per cent after the pandemic, it would take a median of 45 weeks to clear the backlog of operations resulting from COVID-19 disruption. Conclusion: A very large number of operations will be cancelled or postponed owing to disruption caused by COVID-19. Governments should mitigate against this major burden on patients by developing recovery plans and implementing strategies to restore surgical activity safely.
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