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Food safety has become an important food quality attribute. Both food industry and authorities need to be able to trace back and to authenticate food products and raw materials used for food production to comply with legislation and to meet the food safety and food quality requirements. PaniGest is a user-friendly computer package designed to manage traceability and help in the quality control and production improvement. This application was developed in Visual Basic language over an SQL database and its main features are: to register quality control parameters of raw materials, in-course products and final products; to manage reception, production and expedition orders; to analyse production costs, productivity, raw materials and products' consumptions; to trace products during the food chain. It runs on a personal computer over Windows 95/98 or Windows 2000/XP operating system. The program also uses common Internet Browsers to make information available to users. ; Fundação para a Ciência e a Tecnologia ...

Food safety has become an important food quality attribute within the last decade. Facing recent food scandals taken up by the media, consumers are more and more concerned about and interested in the provenance and authenticity of their food. Both food industry and authorities need to be able to trace back and to authenticate food products and raw materials used for food production to comply with legislation and to meet the food safety and food quality requirements as well as the increasing consumer demand. Therefore, food companies are faced with the problem of defining and implementing a series of procedures, controls and measures. Moreover, it is necessary to define an application method which is both rigorous and economically sustainable in order to guarantee the safe production of food and to be able to trace it along the food chain. The application was designed to manage traceability as well as to help in the quality control and production improvement, using an user-friendly interface. This application was developed in Visual Basic over an SQL database and its main features are: to register quality control parameters of raw materials, in-course products and final products; to manage reception, production and expedition orders; to analyse production costs, productivity, raw materials and products' consumptions; to define and print labels containing lot information and other relevant data; to trace products during the food chain (from raw materials to final client). All these informations are accessible either from pre-defined reports either exported to intranet based on Internet Explorer or other browser. Usually the process to assure traceability, specially in food products (due to the large number of ingredients involved in a single formulation) is very time-consuming, involves lots of paperwork and consequently a large number of resources are expended in this laborious task. This application can minimize efforts involved in traceability and managing food quality and safety systems. ; Fundação para a ...

A central issue in audit regulation is whether the introduction of mandatory audit firm rotation enhances audit quality. This paper contributes to the ongoing debate surrounding this issue by analyzing how senior auditors of one of the Big Four accounting firms in Portugal perceive the policy. This study adopts a qualitative methodology based on semi-standardized interviews. In general terms, the interviewees perceive mandatory audit firm rotation negatively due to the loss of client-specific knowledge it causes, the limited association between audit independence and tenure, and the resulting decrease in fees potentially harmful to audit quality ; info:eu-repo/semantics/publishedVersion

Rapid cryopreservation of biological specimens is the gold standard for visualizing cellular structures in their true structural context. However, current commercial cryo-fluorescence microscopes are limited to low resolutions. To fill this gap, we have developed cryoSIM, a microscope for 3D super-resolution fluorescence cryo-imaging for correlation with cryo-electron microscopy or cryo-soft X-ray tomography. We provide the full instructions for replicating the instrument mostly from off-the-shelf components and accessible, user-friendly, open-source Python control software. Therefore, cryoSIM democratizes the ability to detect molecules using super-resolution fluorescence imaging of cryopreserved specimens for correlation with their cellular ultrastructure.

Joint grant from the United Kingdom Medical Research Council and GlaxoSmithKline (Grant No. G0701420) and the National Institute for Health Research (NIHR) Biomedical Research Centre for Mental Health at South London and Maudsley National Health Service (NHS) Foundation Trust and Institute of Psychiatry, King's College London. This work presents independent research in part funded by the NIHR. Also supported by the Wellcome Trust Grant No. 086635 (JJHR); NIHR Specialist Biomedical Research Centre for Mental Health at the South London and Maudsley NHS Foundation Trust and the Institute of Psychiatry, King's College London (SCW); a Marie Curie Intra-European Fellowship within the 7th European Community Framework Programme (MRiv); European Commission Grant Agreement No. 115008 (RU, PM); and Canada Research Chairs program (http://www. chairs-chaires.gc.ca/) (RU). Dr. Aitchison holds an Alberta Centennial Addiction and Mental Health Research Chair, funded by the government of Alberta, Canada. The Genome Based Therapeutic Drugs for Depression study was funded by a European Commission Framework 6 grant, European Commission Contract Reference LSHB-CT-2003-503428, and GlaxoSmithKline. Genotyping was performed at the Centre Nationale De Genotypage, Evry, Paris. We acknowledge the contribution of phase 2 of the Wellcome Trust Case Control Consortium in providing access to control datasets from the 1958 British birth cohort and the National Blood Service cohort.