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Intro -- Contents -- 1: The Utilitarians: Bentham and Mill -- 2: The Individual: Keirkegaard and Nietzsche -- 3: Pragmatism: James and Dewey -- 4: Process Philosophy: Bergson and Whitehead -- 5: Analytic Philosophy: Russell, Logical Positivism, and Wittgenstein -- 6: Husserl and Heidegger -- 7: Existentialism: Sartre, de Beauvoir, and Camus -- Notes -- Glossary -- Bibliography -- Further Reading -- Picture Credits -- Index.
Intro -- Contents -- 1: The Medieval Philosophers -- 2: The Birth of Modern Philosophy: The Renaissance Period -- 3: The British Empiricists: Locke, Berkeley, and Hume -- 4: Critical Philosophy: Immanuel Kant -- 5: Idealism and Materialism: Hegel and Marx -- Notes -- Glossary -- Bibliography -- Further Reading -- Picture Credits -- Index -- About the Author.
In: Journal of the International AIDS Society, Band 25, Heft 7
ISSN: 1758-2652
AbstractIntroductionPostpartum depression (PPD) is a prevalent and debilitating disease that may affect medication adherence and thus maternal health and vertical transmission among women with HIV. We assessed the feasibility of a trial of interpersonal psychotherapy (IPT) versus antidepressant medication (ADM) to treat PPD and/or anxiety among postpartum women with HIV in Lusaka, Zambia.MethodsBetween 29 October 2019 and 8 September 2020, we pre‐screened women 6–8 weeks after delivery with the Edinburgh Postnatal Depression Scale (EPDS) and diagnosed PPD or anxiety with the Mini International Neuropsychiatric Interview. Consenting participants were randomized 1:1 to up to 11 sessions of IPT or daily self‐administered sertraline and followed for 24 weeks. We assessed EPDS score, Clinical Global Impression‐Severity of Illness (CGI‐S) and medication side effects at each visit and measured maternal HIV viral load at baseline and final study visit. Retention, visit adherence, change in EPDS, CGI‐S and log viral load were compared between groups with t‐tests and Wilcoxon signed rank tests; we report mean differences, relative risks and 95% confidence intervals. A participant satisfaction survey assessed trial acceptability.Results78/80 (98%) participants were retained at the final study visit. In the context of the COVID‐19 pandemic, visit adherence was greater among women allocated to ADM (9.9 visits, SD 2.2) versus IPT (8.9 visits, SD 2.4; p = 0.06). EPDS scores decreased from baseline to final visit overall, though mean change was greater in the IPT group (−13.8 points, SD 4.7) compared to the ADM group (−11.4 points, SD 5.5; p = 0.04). Both groups showed similar changes in mean log viral load from baseline to final study visit (mean difference −0.43, 95% CI −0.32, 1.18; p = 0.48). In the IPT group, viral load decreased significantly from baseline (0.9 log copies/ml, SD 1.7) to final visit (0.2 log copies/ml, SD 0.9; p = 0.01).ConclusionsThis pilot study demonstrates that a trial of two forms of PPD treatment is feasible and acceptable among women with HIV in Zambia. IPT and ADM both improved measures of depression severity; however, a full‐scale trial is required to determine whether treatment of PPD and anxiety improves maternal–infant HIV outcomes.