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Funding Information: Acknowledgment This work was supported in part by the National Key R & D Program of China through Grant No. 2019YFB2101901; the National NSFC through Grants No. 62072332 and 62002260; and the China Postdoctoral Science Foundation under Grant No. 2020M670654. This work was also partially supported by the European Union Horizon 2020 Research and Innovation Program through the MonB5G Project under Grant No. 871780; the Academy of Finland Project CSN under Grant Agreement 311654; and the 6Genesis project under Grant No. 318927. Publisher Copyright: © 1986-2012 IEEE. Copyright: Copyright 2021 Elsevier B.V., All rights reserved. | openaire: EC/H2020/871780/EU//MonB5G ; Along with the unprecedented development of artificial intelligence (AI), a considerable number of intelligent applications are universally recognized to significantly facilitate the evolution of anthropogenic activities. The abundant AI computing power is one of the main pillars to fuel the booming of ubiquitous AI applications. As the computing power proliferates to a multitude of network edges, even end devices, the networking function bridges the gap, on the one hand, among ends-edges-clouds, on the other hand, between the multiple AI computing power and the heterogeneous AI requirements. The emerging new opportunities have spawned the deep integration between computing and networking. However, the complete development of the integrated system is under-addressed, including adaptability, flexibility, and profitability. In this article, we propose a computing-power networking framework for ubiquitous AI by establishing Networking in AI computing-power pool, denoted as Net-in-AI. We design the framework to enable the adaptability for computing-power users, the flexibility for networking, and the profitability for computing-power providers. We then formulate a computing-networking resource allocation problem, with the joint perspective of these three aspects. Experimental results prove the superior performance of the proposed framework in comparison to the current popular schemes. ; Peer reviewed

Yanrong Cai,1 Lieping Guo,2 Hongxing Shen,2 Xiaofei An,2 Hong Jiang,3 Fang Ji,2 Yunfei Niu21The College of Basic Science of Medicine, Hunan University of Traditional Chinese Medicine, Changsha, 2Department of Orthopaedics, Changhai Hospital, Second Military Medical University, 3School of Materials Science and Engineering, University of Shanghai for Science and Technology, Shanghai, People's Republic of ChinaAbstract: Biocomposite scaffolds of lithium (Li)-containing mesoporous bioglass and monomethoxy poly(ethylene glycol)-poly(D,L-lactide-co-glycolide)-poly(L-lysine) (mPEG-PLGA-b-PLL) copolymer were fabricated in this study. The results showed that the water absorption and degradability of Li-containing mesoporous bioglass/mPEG-PLGA-b-PLL composite (l-MBPC) scaffolds were obviously higher than Li-containing bioglass/mPEG-PLGA-b-PLL composite (l-BPC) scaffolds. Moreover, the apatite-formation ability of l-MBPC scaffolds was markedly enhanced as compared with l-BPC scaffolds, indicating that l-MBPC scaffolds containing mesoporous bioglass exhibited good bioactivity. The cell experimental results showed that cell attachment, proliferation, and alkaline phosphatase activity of MC3T3-E1 cells on l-MBPC scaffolds were remarkably improved as compared to l-BPC scaffolds. In animal experiments, the histological elevation results revealed that l-MBPC scaffolds significantly promoted new bone formation, indicating good osteogenesis. l-MBPC scaffolds with improved properties would be an excellent candidate for bone tissue repair.Keywords: MBG, copolymer, degradability, bioactivity, osteogenesis, cell proliferation, bone repair

Yan Xia,1 Panyu Zhou,1,* Fei Wang,2 Chao Qiu,2 Panfeng Wang,1 Yuntong Zhang,1 Liming Zhao,3 Shuogui Xu1,2 1Department of Emergency, 2Department of Orthopedics, Changhai Hospital, Second Military Medical University, 3State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, People's Republic of China *These authors contributed equally to this work Abstract: In this study, bioactive scaffold of nano magnesium phosphate (nMP)/wheat protein (WP) composite (MWC) was fabricated. The results revealed that the MWC scaffolds had interconnected not only macropores (sized 400–600 µm) but also micropores (sized 10–20 µm) on the walls of macropores. The MWC scaffolds containing 40 w% nMP had an appropriate degradability in phosphate-buffered saline and produced a weak alkaline microenvironment. In cell culture experiments, the results revealed that the MWC scaffolds significantly promoted the MC3T3-E1 cell proliferation, differentiation, and growth into the scaffolds. The results of synchrotron radiation microcomputed tomography and analysis of the histological sections of the in vivo implantation revealed that the MWC scaffolds evidently improved the new bone formation and bone defects repair as compared with WP scaffolds. Moreover, it was found that newly formed bone tissue continued to increase with the gradual reduction of materials residual in the MWC scaffolds. Furthermore, the immunohistochemical analysis further offered the evidence of the stimulatory effects of MWC scaffolds on osteogenic-related cell differentiation and new bone regeneration. The results indicated that MWC scaffolds with good biocompability and degradability could promote osteogenesis in vivo, which would have potential for bone tissue repair. Keywords: nano magnesium phosphate, wheat protein, composite scaffolds, degradation, bone regeneration