Suchergebnisse

Despite major international investment in biofuels, the invasive risks associated with these crops are still unknown. A cohesive state-of-the-art review of the invasive potential of bioenergy crops, this book covers the identified risks of invasion, distributions of key crops and policy and management issues. Including a section on developing predictive models, this book also assesses the potential societal impact of bioenergy crops and how to mitigate invasive risks

This is the author accepted manuscript. The final version is available from OUP via the DOI in this record. ; Background. Self-management and self-efficacy for physical activity is not routinely considered in neurologic rehabilitation. Objective. This study assessed feasibility and outcomes of a 14-week physical activity self-management and coaching intervention compared with social contact in Huntington disease (HD) to inform the design of a future full-scale trial. Design. Assessor blind, multisite, randomized pilot feasibility trial. Setting. Participants were recruited and assessed at baseline, 16 weeks following randomization, and then again at 26 weeks in HD specialist clinics with intervention delivery by trained coaches in the participants' homes. Patients and Intervention. People with HD were allocated to the ENGAGE-HD physical activity coaching intervention or a social interaction intervention. Measurements. Eligibility, recruitment, retention, and intervention participation were determined at 16 weeks. Other outcomes of interest included measures of mobility, self-efficacy, physical activity, and disease-specific measures of motor and cognition. Fidelity and costs for both the physical activity and social comparator interventions were established. Results. Forty percent (n = 46) of eligible patients were enrolled; 22 were randomized to the physical intervention and 24 to social intervention. Retention rates in the physical intervention and social intervention were 77% and 92%, respectively. Minimum participation criteria were achieved by 82% of participants in the physical intervention and 100% in the social intervention. There was no indication of between-group treatment effects on function; however, increases in self-efficacy for exercise and self-reported levels of physical activity in the physical intervention lend support to our predefined intervention logic model. Limitations. The use of self-report measures may have introduced bias. Conclusions. An HD physical activity self-management and coaching intervention is feasible and worthy of further investigation. ; Funding was provided by Health and Care Research Wales. Dr Dawes was supported by the Elizabeth Casson Trust and the NatIonal Institute for Social and Health care Research (NIHR), Oxford Biomedical Research Centre, based at Oxford University Hospitals NHS Trust and the University of Oxford. The South East Wales Trials Unit (SEWTU), Centre for Trials Research, Cardiff University, is funded by the Wales Assembly Government through Health and Care Research Wales.