Suchergebnisse

The study is the investigation of Biden's speech delivered at Jordan's King Abdullah II visit amid the Israel-Palestine war for an immediate ceasefire. The study aims to explore the US perspective on the Israel-Palestine war through Biden's speech. Purposive sampling of US President Biden's recent speech delivered on February 13th, 2024, is done to investigate the contemporary perspective of the US on the Israel-Palestine war using Fairclough's three-dimensional model. Findings revealed that, at the description level, values of words and grammar through contrastive schemes represent specific ideologies associated with Hamas and Israel. At the interpretation level, text and context indicate Hamas as the only one responsible for the chaos and Israel as the bearer of circumstances. At the explanation phase, the speech seems normative as the US projects its diplomatic role as a global power in sustaining peace and seems to support Israel due to shared cultural values.

OBJECTIVES: Considering the therapeutic potential of honey and Nigella sativa (HNS) in coronavirus disease 2019 (COVID-19) patients, the objective of the study is defined to evaluate the prophylactic role of HNS. TRIAL DESIGN: The study is a randomized, placebo-controlled, adaptive clinical trial with parallel group design, superiority framework with an allocation ratio of 1:1 among experimental (HNS) and placebo group. An interim analysis will be done when half of the patients have been recruited to evaluate the need to adapt sample size, efficacy, and futility of the trial. PARTICIPANTS: : High-risk exposure (10min without face protection). Moderate exposure (10min with face protection). Subjects with acute or chronic infection, COVID-19 vaccinated, and allergy to HNS will be excluded from the study. Recruitment will be done at Shaikh Zayed Post-Graduate Medical Institute, Ali Clinic and Doctors Lounge in Lahore (Pakistan). INTERVENTION AND COMPARATOR: In this clinical study, patients will receive either raw natural honey (0.5 g) and encapsulated organic Nigella sativa seeds (40 mg) per kg body weight per day or empty capsule with and 30 ml of 5% dextrose water as a placebo for 14 days. Both the natural products will be certified for standardization by Government College University (Botany department). Furthermore, each patient will be given standard care therapy according to version 3.0 of the COVID-19 clinical management guidelines by the Ministry of National Health Services of Pakistan. MAIN OUTCOMES: Primary outcome will be Incidence of COVID-19 cases within 14 days of randomisation. Secondary endpoints include incidence of COVID-19-related symptoms, hospitalizations, and deaths along with the severity of COVID-19-related symptoms till 14(th) day of randomization. RANDOMISATION: Participants will be randomized into experimental and control groups (1:1 allocation ratio) via the lottery method. There will be stratification based on high risk and ...