Suchergebnisse

1 Alcohol Use and Abuse: Historical Perspective and Present Trends -- 1. Alcohol Use in Historical Perspective -- 2. Alcohol Consumption and Alcohol Problems -- 3. Development of the Concept(s) of Alcoholism -- 4. References -- 2 The Genetics of Alcoholism -- 1. Types of Studies Supporting a Genetic Influence in Alcoholism -- 2. Possible Biological Mechanisms for a Genetic Influence in Alcoholism -- 3. A Prospective Search for the Biological Determinants of Alcoholism -- 4. Summary -- 5. References -- 3 The Absorption, Distribution, and Metabolism of Ethanol and Its Effects on Nutrition and Hepatic Function -- 1. Introduction -- 2. Absorption and Distribution -- 3. Pharmacokinetics and Alcohol Elimination Rates -- 4. Processes and Organs Responsible for Ethanol Elimination -- 5. Significant Pathways of Ethanol Metabolism -- 6. Enzymes That Oxidize Ethanol to Acetaldehyde -- 7. Enzymes That Oxidize Acetaldehyde to Acetate -- 8. Control of Ethanol and Acetaldehyde Metabolism in Liver -- 9. Effect of Chronic Ethanol Ingestion on Alcohol Elimination Rate -- 10. Chronic Ethanol Ingestion and Nutrition -- 11. Ethanol Oxidation and Hepatic Metabolism -- 12. References -- 4 Effects of Ethanol upon Organ Systems Other than the Central Nervous System -- 1. Introduction -- 2. Ethanol and the Gastrointestinal Tract -- 3. Muscle Systems -- 4. The Hematologic System -- 5. Kidney Disease and Alcoholism -- 6. Pulmonary Disease and Alcoholism -- 7. The Endocrine System and Alcoholism -- 8. Effects of Ethanol on the Hypothalamic-Pituitary-Adrenal Axis -- 9. Effects of Alcohol on the Hypothalamic-Pituitary-Thyroidal Axis -- 10. The Effects of Alcohol on Growth Hormone and Prolactin -- 11. Effects of Alcohol on Vasopressin and Oxytocin -- 12. Biological Markers of Alcoholism -- 13. References -- 5 Ethanol and the Central Nervous System -- 1. Ethanol and Behavior -- 2. Ethanol and Membrane Structure and Function -- 3. Ethanol and Electrical Cellular Activity -- 4. Ethanol and Synaptic Transmission -- 5. Ethanol and Metabolism -- 6. Consequences of Long-term Ethanol Consumption -- 7. Summary -- 8. References -- 6 Neurologic Diseases Associated with Chronic Alcohol Abuse -- 1. Introduction -- 2. Physical Dependence -- 3. Chronic Diseases of the Central Nervous System -- 4. Peripheral Polyneuropathy -- 5. Nutritional Deficiencies -- 6. Conclusions -- 7. References -- 7 Biology of Tolerance and Dependence -- 1. Introduction to Tolerance and Dependence -- 2. Factors Contributing to Tolerance and Dependence -- 3. Classifications and Definitions of Tolerance -- 4. Biochemical Determinants of Ethanol Tolerance -- 5. Characteristics of Physical Dependence on Ethanol -- 6. Etiological Factors Contributing to the Development of Physical Dependence -- 7. Neurochemical Systems Determining Physical Dependence -- 8. Pharmacologic Management of the Acute Alcohol Withdrawal Syndrome -- 9. References -- 8 Alcohol Consumption and Prenatal Development -- 1. Fetal Alcohol Syndrome/Fetal Alcohol Effects -- 2. Alcohol as a Teratogen in Animals, 1973–1979 -- 3. Critical Discussion and General Conclusions -- 4. References -- 9 Interaction of Ethanol with Other Drugs -- 1. Introduction -- 2. Centrally Acting Compounds -- 3. References -- 10 Psychological Correlates and Explantions of Alcohol Use and Abuse -- 1. Psychodynamic Models -- 2. The Disease Model -- 3. Behavioral and Social-Learning Approach -- 4. Future Directions -- 5. References -- 11 Alcoholism Treatment Approaches: Patient Variables, Treatment Variables -- 1. Critical View of Treatment Outcome Evaluation -- 2. Treatment Variables -- 3. Patient Variables -- 4. Implications -- 5. References -- 12 Prevention of Alcohol Abuse -- 1. Approaches to Prevention -- 2. Alcohol Education -- 3. Mass Media -- 4. Alcohol Control Legislation -- 5. Conclusions -- 6. References.

Objective: This study investigated whether different alcoholism treatment approaches differentially impact social support scores in individuals with concurrent alcohol dependence and social phobia. Method: Individuals (N = 397) were selected retrospectively from a larger pool of participants enrolled in a multisite randomized clinical trial on treatment matching. Three standard treatments were delivered over 12 weeks: Cognitive-Behavioral Therapy (CBT), Twelve Step Facilitation Therapy (TSF), and Motivational Enhancement Therapy (MET). Social support measures were analyzed to test the effects of treatment group and gender. Results: For men, there was significant improvement on two measures of social support regardless of treatment group. Women who received CBT or TSF had better support outcomes than women who received MET. Conclusions: These data suggest that social support can be improved through alcohol treatment in individuals with coexisting social phobia, particularly if social workers emphasize skills training and facilitating involvement in 12-step groups.