Suchergebnisse

"Where the devil are my slippers, Eliza?" -- "There's nothing better than a single life." -- The foot-long Weltanschauung -- Bachelors in paradise : if life were best lived as couples, we'd all be Siamese twins -- Gershwin's girlfriend, Casanova's cuties & C

Celebrated for its commitment to independence and fearless individualism, America in fact dismisses independent thinkers and nonconformists in favor of the team player, the company man, and the go-along-to-get-along mentality. This anti-intellectual mindset despises and discredits those who are solitary and reclusive. While we look up to literary loners like Poe and Melville and Dickinson, the man in the street is a compulsive joiner of clubs, and herds from university frats to the Order of the Pink Goat. To the contrary, this book is a paean vigorously endorsing America's lone wolves, cultura

AbstractThe National Academy of Sciences — National Research Council (NAS-NRC) twin panel, created nearly 50 years ago, had twin zygosity determined primarily via a similarity questionnaire that has been estimated to correctly classify at least 95% of twins. In the course of a study on the genetics of healthy ageing in the NAS-NRC twins, DNA was collected for genome-wide scanning and zygosity confirmation was examined in 343 participating pairs. The sample was supplemented from two other studies using NAS-NRC twins where one or both co-twins were suspected to have Alzheimer disease or another dementia, or Parkinson's disease. Overall 578 twin pairs with DNA were analyzed. Zygosity assignment for 96.8% (519/536) was confirmed via questionnaire. Among 42 pairs whose questionnaire responses were inconclusive for assigning zygosity, 50% were found to be monozygous (MZ) and 50% were dizygous (DZ). There was some evidence for greater misclassification of presumed DZ pairs in the healthy ageing study where participation favored pairs who were similar in having a favorable health history and willingness to volunteer without any element of perceived risk for a specific disease influencing participation.