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Physiologically Based Liver Modeling and Risk Assessment
In: Risk analysis: an international journal, Band 12, Heft 1, S. 139-148
ISSN: 1539-6924
Because of the inherent complexity of biological systems, there is often a choice between a number of apparently equally applicable physiologically based models to describe uptake and metabolism processes in toxicology or risk assessment. These models may fit the particular data sets of interest equally well, but may give quite different parameter estimates or predictions under different (extrapolated) conditions. Such competing models can be discriminated by a number of methods, including potential refutation by means of strategic experiments, and their ability to suitably incorporate all relevant physiological processes. For illustration, three currently used models for steady‐state hepatic elimination—the venous equilibration model, the parallel tube model, and the distributed sinusoidal perfusion model—are reviewed and compared with particular reference to their application in the area of risk assessment. The ability of each of the models to describe and incorporate such physiological processes as protein binding, precursor‐metabolite relations and hepatic zones of elimination, capillary recruitment, capillary heterogeneity, and intrahepatic shunting is discussed. Differences between the models in hepatic parameter estimation, extrapolation to different conditions, and interspecies scaling are discussed, and criteria for choosing one model over the others are presented. In this case, the distributed model provides the most general framework for describing physiological processes taking place in the liver, and has so far not been experimentally refuted, as have the other two models. These simpler models may, however, provide useful bounds on parameter estimates and on extrapolations and risk assessments.
Insights into the complementarity of natural disaster insurance purchases and risk reduction behavior
In: Risk analysis: an international journal, Band 44, Heft 1, S. 141-154
ISSN: 1539-6924
AbstractWhile flooding is the costliest natural disaster risk, public‐sector investments provide incomplete protection. Moreover, individuals are in general reluctant to voluntarily invest in measures which limit damage costs from natural disasters. The moral hazard hypothesis argues that insured individuals take fewer other preparedness measures based on their assumption that their losses will be covered anyway. Conversely, the advantageous selection hypothesis argues that individuals view insurance and other risk reduction measures as complements. This study offers a comprehensive assessment of factors related to the separate uptake of natural disaster insurance and the flood‐proofing of homes as well as why people may take both of these measures together. We use data from a survey conducted in Paris, France, in 2018, after several flood events, for a representative sample of 2976 residents facing different levels of flood risk. We perform both main effects regressions and interaction analyses to reveal that home adaptation to flooding is positively associated with comprehensive insurance coverage, which includes financial protection against natural disasters. Furthermore, actual and perceived risks, as well as awareness of official information on flood risk, are found to explain some of the relationship between home adaptation and comprehensive insurance purchase. We suggest several recommendations to policymakers based on these insights which aim to address insurance coverage gaps and the failure to take disaster risk reduction measures. In particular, groups in socially vulnerable situations may benefit from subsidized insurance, low interest loans, and decision aids to implement costly adaptation measures.
Drivers of natural disaster risk‐reduction actions and their temporal dynamics: Insights from surveys during an imminent hurricane threat and its aftermath
In: Risk analysis: an international journal
ISSN: 1539-6924
AbstractTo improve preparedness for natural disasters, it is imperative to understand the factors that enable individual risk‐reduction actions. This study offers such insights using innovative real‐time (N = 871) and repeated (N = 255) surveys of a sample of coastal residents in Florida regarding flood preparations and their drivers during an imminent threat posed by Hurricane Dorian and its aftermath. Compared with commonly employed cross‐sectional surveys, our methodology better represents relationships between preparedness actions undertaken during the disaster threat and their drivers derived from an extended version of Protection Motivation Theory (PMT). The repeated survey allows for examining temporal dynamics in these drivers. Our results confirm the importance of coping appraisals and show that risk perceptions relate more strongly to emergency protection decisions made during the period of the disaster threat than to decisions made well before. Moreover, we find that several personal characteristics that we add to the standard PMT framework significantly relate to undertaking preparedness actions, especially locus of control and social norms. Significant changes in key explanatory variables occur following the disaster threat, including a decline in risk perception, a potential learning effect in coping appraisals, and a decline in risk aversion. Our results confirm the advantage of the real‐time and repeated survey approach in understanding both short‐ and long‐term disaster preparedness actions.
Behavioral biases and heuristics in perceptions of COVID‐19 risks and prevention decisions
In: Risk analysis: an international journal, Band 42, Heft 12, S. 2671-2690
ISSN: 1539-6924
AbstractThis study adds to an emerging literature on the factors associated with individual perceptions of COVID‐19 risks and decision‐making processes related to prevention behaviors. We conducted a survey in the Netherlands (N = 3600) in June–July 2020 when the first peak of COVID‐19 infections, hospitalizations, and deaths had passed, and lockdown measures had been eased. Dutch policies relied heavily on individual prevention behaviors to mitigate a second infection wave. We examine whether biases and heuristics that have been observed in how people perceive and respond to other risks also apply to the newly emergent risks posed by COVID‐19. The results indicate that people simplify risk using threshold models and that risk perceptions are related with personal experiences with COVID‐19 and experiences of close others, supporting the availability heuristic. We also observe that prevention behavior is more strongly associated with COVID‐19 risk perceptions and feelings toward the risk than with local indicators of COVID‐19 risks, and that prevention behavior is related with herding. Support for government lockdown measures is consistent with preferences that may contribute to the not‐in‐my‐term‐of‐office bias. In addition, we offer insights into the role of trust, worry, and demographic characteristics in shaping perceptions of COVID‐19 risks and how these factors relate with individual prevention behaviors and support for government prevention measures. We provide several lessons for the design of policies that limit COVID‐19 risks, including risk communication strategies and appeals to social norms. Perhaps more importantly, our analysis allows for learning lessons to mitigate the risks of future pandemics.
Factors of influence on flood risk perceptions related to Hurricane Dorian: an assessment of heuristics, time dynamics, and accuracy of risk perceptions
In: Natural hazards and earth system sciences: NHESS, Band 24, Heft 4, S. 1303-1318
ISSN: 1684-9981
Abstract. Flood damage caused by hurricanes is expected to rise globally due to climate and socio-economic change. Enhanced flood preparedness among the coastal population is required to reverse this trend. The decisions and actions taken by individuals are thought to be influenced by risk perceptions. This study investigates the determinants that shape flood risk perceptions and the factors that drive flood risk misperceptions of coastal residents. We conducted a survey among 871 residents in flood-prone areas in Florida during a 5 d period in which the respondents were threatened to be flooded by Hurricane Dorian. This approach allows us to assess temporal dynamics in flood risk perceptions during an evolving hurricane threat. Among 255 of the same households, a follow-up survey was conducted to examine how flood risk perceptions varied after Hurricane Dorian failed to make landfall in Florida. Our results show that the flood experience and social norms have the most consistent relationship with flood risk perceptions. Furthermore, participants indicated that their level of worry regarding the dangers of flooding decreased after the near-miss of Hurricane Dorian compared to their feelings of worry during the hurricane event. Based on our findings, we offer recommendations for improving flood risk communication policies.
Surveying the surveyors to address risk perception and adaptive-behaviour cross-study comparability
In: Natural hazards and earth system sciences: NHESS, Band 22, Heft 8, S. 2655-2672
ISSN: 1684-9981
Abstract. One of the key challenges for risk, vulnerability and resilience research is how to address the role of risk perceptions and how perceptions influence behaviour. It remains unclear why people fail to act adaptively to reduce future losses, even when there is ever-richer information available on natural and human-made hazards (flood, drought, etc.). The current fragmentation of the field makes it an uphill battle to cross-validate the results of existing independent case studies. This, in turn, hinders comparability and transferability across scales and contexts and hampers recommendations for policy and risk management. To improve the ability of researchers in the field to work together and build cumulative knowledge, we question whether we could agree on (1) a common list of minimal requirements to compare studies, (2) shared criteria to address context-specific aspects of countries and regions, and (3) a selection of questions allowing for comparability and long-term monitoring. To map current research practices and move in this direction, we conducted an international survey – the Risk Perception and Behaviour Survey of Surveyors (Risk-SoS). We find that most studies are exploratory in nature and often overlook theoretical efforts that would enable the comparison of results and an accumulation of evidence. While the diversity of approaches is an asset, the robustness of methods is an investment to be made. Surveyors report a tendency to reproduce past research design choices but express frustration with this trend, hinting at a turning point. To bridge the persistent gaps, we offer several recommendations for future studies, particularly grounding research design in theory; improving the formalisation of methods; and formally comparing theories and constructs, methods, and explanations while collecting the themes and variables most in use.