Suchergebnisse

The Karlsruhe Institute of Technology (KIT) is participating on (Code Applications and Maintenance Program) CAMP of the US Nuclear Regulatory Commission (NRC) to validate TRACE code for LWR transient analysis. The application of TRACE for the safety assessment of BWR requires a throughout verification and validation using experimental data from separate effect and integral tests but also using plant data. The validation process is normally focused on safety-relevant phenomena for example, pressure drop, void fraction, heat transfer, and critical power models. The purpose of this paper is to validate selected BWR-relevant TRACE-models using both data of bundle tests such as the (Boiling Water Reactor Full-Size Fine-Mesh Bundle Test) BFBT and plant data recorded during a turbine trip event (TUSA) occurred in a Type-72 German BWR plant. For the validation, TRACE models of the BFBT bundle and of the BWR plant were developed. The performed investigations have shown that the TRACE code is appropriate to describe main BWR-safety-relevant phenomena (pressure drop, void fraction, and critical power) with acceptable accuracy. The comparison of the predicted global BWR plant parameters for the TUSA event with the measured plant data indicates that the code predictions are following the main trends of the measured parameters such as dome pressure and reactor power.

The Institute of Neutron Physics and Reactor Technology (INR) is involved in the qualification of coupled codes for reactor safety evaluations, aiming to improve their prediction capability and acceptability. In the frame of the VVER-1000 Coolant Transient Benchmark Phase 1, RELAP5/PARCS has been extensively assessed. Phase 2 of this benchmark was focused on both multidimensional thermal hydraulic phenomena and core physics. Plant data will be used to qualify the 3D models of TRACE and RELAP5/CFX, which were coupled for this purpose. The developed multidimensional models of the VVER-1000 reactor pressure vessel (RPV) as well as the performed calculations will be described in detail. The predicted results are in good agreement with experimental data. It was demonstrated that the chosen 3D nodalization of the RPV is adequate for the description of the coolant mixing phenomena in a VVER-1000 reactor. Even though only a 3D coarse nodalization is used in TRACE, the integral results are comparable to those obtained by RELAP5/CFX.

AbstractFoetal birth weight is an important determinant of perinatal health. For this reason, various methods have been investigated for estimating this weight during pregnancy. The aim of this study is to evaluate the possible relationship between full-term birth weight and pregnancy-associated plasma protein-A (PAPP-A) levels determined during the first trimester as part of combined screening for aneuploidy carried out in pregnant women. We carried out a single-centre study including pregnant women who were being followed up by the Obstetrics Service Care Units of the XXI de Santiago de Compostela e Barbanza Foundation, who gave birth from March 1, 2015, to March 1, 2017, and who had undergone their first-trimester combined chromosomopathy screening. The sample included a total of 2794 women. We found a significant correlation between MoM PAPP-A and foetal birth weight. When MoM PAPP-A was measured at extremely low levels (< 0.3) during the first trimester, the OR for giving birth to a foetus with weight < p10, adjusting for gestational age and sex, was 2.74. For low levels of MoM PAPP-A (0.3–0.44), the OR was 1.52. With regard to the value of MOM PAPP-A levels as a predictor of foetal macrosomia, a correlation could be observed with elevated levels, although this was not statistically significant. PAPP-A determined during the first trimester acts as a predictor of foetal weight at term as well as for foetal growth disorders.

[EN] Horizontal hydroacoustics is a technique of remote fish detection that has proved to efficiently determine fish density and biomass in shallow or superficial waters. This non-intrusive technique could render better results than those obtained by conventional sampling when monitoring shallow waters. To apply this technique, we need equations that relate the amount of sound returned by fish, known as target strength (TS in dB), with their length (mm) or weight (g). This study presents horizontal conversion equations for the species gilt-head bream (Sparus aurata) and sea bass (Dicentrarchus labrax), two of the most important species bred in aquaculture. Moreover, this study presents a new formula to calculate a mixed equation adjusted to the percentage of distribution of those species in case of mixed populations. The results in this research have been obtained by applying a simple setup that allows for high-quality acoustic data. These new equations will enable the application of this technique in order to estimate these species' density and biomass in shallow aquatic systems such as aquaculture ponds with semi-intensive production densities. ; This study's authors would like to thank the Superintendent of Economy and Knowledge (Andalusian Government) for the funding provided as part of the project (PI_57052) developed in collaboration with CTAQUA. We would like to thank the researchers Carlos Orduna Marin and Juan Ramon Cid Quintero for their selfless work to obtain the field data and to the company PIMSA for generously allowing us to use their facilities and fish. We would also like to thank the veterinarian JR Rodriguez for being kind enough to perform X-rays on the studied fish and Cristina Ocana for her careful proofreading of the English text. ; Rodríguez-Sánchez, V.; Rodríguez-Ruiz, A.; Pérez Arjona, I.; Encina-Encina, L. (2018). Horizontal target strength-size conversion equations for sea bass and gilt-head bream. Aquaculture. 490:178-184. https://doi.org/10.1016/j.aquaculture.2018.02.034 ; S ; 178 ...

The European construction sector (a fragmented SMEs dominated business with high economic and environmental impact and high technological inertia) faces a major challenge to reduce the emissions by almost 90% in 2050. This requires new innovative solutions and services to be rapidly implemented in the market. Research Infrastructures that give support for later-stage developments (high Technology Readiness Levels) can play a relevant role in both the technological development and market introduction of construction products for energy efficient buildings. The following paper describes such an infrastructure (KUBIKby (Tecnalia)) located in Bilbao (Spain) and its major outcomes in the period 2011-2015. ; Spanish Ministry of Education and Science, Spanish Ministry of Science and Innovation, European Regional Development Fund, European Union Seventh Framework Program, Basque Government

Background Preventing infantile anaemia and ensuring optimal growth and development during early childhood, particularly in resource-constrained settings, represent an ongoing public health challenge. Current responses are aligned to treatment-based solutions, instead of determining the roles of its inter-related causes. This project aims to assess and understand the complex interplay of eco-bio-social-political factors that determine infantile anaemia to inform policy, research design and prevention practices. Methods This is a longitudinal birth cohort study including four components: (1) biological, will assess known blood markers of iron homeostasis and anaemia and stool microbiota to identify and genetically analyse the participants' flora; (2) ecological, will assess and map pollutants in air, water and soil and evaluate features of nutrition and perceived food security; (3) social, which will use different qualitative research methodologies to explore key stakeholders and informants' perceptions related to nutritional, environmental and anaemia topics, participant observations and a participatory approach and (4) a political analysis, to identify and assess the impact of policies, guidelines and programmes at all levels for infantile anaemia in the three regions. Finally, we will also explore the role of social determinants and demographic variables longitudinally for all study participants. This project aims to contribute to the evidence of the inter-related causal factors of infantile anaemia, addressing the complexity of influencing factors from diverse methodological angles. We will assess infantile anaemia in three regions of Peru, including newborns and their mothers as participants, from childbirth until their first year of age. Ethics and dissemination Ethical approval was obtained from the Institutional Research Ethics Committee of the Instituto Nacional de Salud del Niño (Lima, Peru), CIEI-043-2019. An additional opinion has been granted by the Ethical Committee of Queen Mary University of London (London, UK). Dissemination across stakeholders is taking part as a continues part of the research process. © ; Funding This project is supported by the Medical Research Council—MRC grant number MR/S024654/1 and by the Fondo Nacional de Desarrollo Científico, Tecnológico y de Innovación Tecnológica—FONDECYT, grant number 033-2019. AJP is funded by the Wellcome Trust (108065/Z/15/Z).

[SPA] Listeria monocytogenes es actualmente una de las principales preocupaciones de la industria alimentaria. Aunque el número de casos reportados en la Unión Europea es relativamente, tiene una gran gravedad, con unas tasas de hospitalización y mortandad del 97% y del 16,7%, respectivamente. Debido a la ubicuidad de este microorganismo y su capacidad de crecer en numerosas matrices alimentarias, las empresas agroalimentarias deben aplicar tratamientos que inactiven las células de L. monocytogenes. En este trabajo, se estudió la cinética de inactivación de L. monocytogenes aislada de productos marinos sometida a un tratamiento combinado de PEAV con un aceite esencial de orégano. Los resultados demuestran esta sinergia, ya que se consiguió una mayor inactivación microbiana con un campo de 20 kV/cm, 1 Hz de frecuencia, 150 pulsos y una concentración de orégano de 1/2 MIC, superior a la obtenida en las muestras control. Llegando a la conclusión de que los PEAV impulsan el efecto del orégano sobre la membrana de la bacteria. [ENG] Nowadays Listeria monocytogenes is one of the main concerns of the food industry. The number of cases reported in the European Union is relatively low it is very serious, with rates of hospitalization and mortality of 97% and 16.7%, respectively. Due to the ubiquity of this organism and its capacity to grow in many food matrices, agri-food companies must apply treatments that inactivate the cells of L. monocytogenes. In this work, it was studied the kinetics of inactivation of L. monocytogenes isolated from marine products subjected to a combined treatment of PEF with an essential oil of oregano. The results show this synergy, since it got a greater inactivation microbial with a field of 20 KV/cm, 1 Hz frequency, 150 pulses and an oregano concentration of 1/2 MIC, higher than that obtained in control samples. Concluding that the PEF promote the effect of oregano on the bacterial cell membrane. ; Investigación apoyada por el MICINN (es) y FEDER a través de los proyectos ...