Suchergebnisse

Background: Recent studies analysing the trends in antipsychotic (AP) prescriptions for children and adolescents have raised concerns regarding the influence of socioeconomic status. Previous findings have also shown variable prescription rates for first-generation (FG) and second-generation (SG) APs.Method: Our objectives were to assess the proportion of patients from low-income families receiving APs and the most commonly prescribed APs in France. We conducted a descriptive analysis of AP drugs dispensed during a 1-year period (July 1, 2013-June 30, 2014) in a northwestern region of France with 941,857 subjects less than 18 years old. All data were extracted from an exhaustive, individual and anonymous social security database. We obtained each subject's socioeconomic status (by identifying their affiliation with a specific social security program) and also collected sociodemographic data, drug type, prescribing and dispensing dates and amount, and prescriber type (e.g., hospital physician, general practitioner, psychiatrist, paediatrician).Results: There were two main novel findings. First, we found that the proportion of patients with AP prescriptions was nearly ten times higher in low-income families than in the general population: 35.9% of CMU-C patients compared to 3.7% in all of Pays de la Loire (X-2 = 7875.1, p < 0.001). Additionally, we found a higher rate of FGAP than SGAP prescriptions (65% vs. 57%).Conclusions: Our study suggests two types of AP misuse that could provide interesting targets for public healthcare interventions.First, our results strongly suggest an over-representation of patients from low-income families. Low-income families primarily resided in areas with low physician density and appeared to receive drugs to treat their conditions more frequently than other individuals. This increased prescription rate is a public health issue, potentially requiring political action. Second, the use of FGAPs did not adhere to the latest recommendations for drug use in this population, and this discrepancy should be addressed with informational campaigns targeted to medical practitioners.

International audience ; Recent studies analysing the trends in antipsychotic (AP) prescriptions for children and adolescents have raised concerns regarding the influence of socioeconomic status. Previous findings have also shown variable prescription rates for first-generation (FG) and second-generation (SG) APs. Method Our objectives were to assess the proportion of patients from low-income families receiving APs and the most commonly prescribed APs in France. We conducted a descriptive analysis of AP drugs dispensed during a 1-year period (July 1, 2013–June 30, 2014) in a northwestern region of France with 941,857 subjects less than 18 years old. All data were extracted from an exhaustive, individual and anonymous social security database. We obtained each subject's socioeconomic status (by identifying their affiliation with a specific social security program) and also collected sociodemographic data, drug type, prescribing and dispensing dates and amount, and prescriber type (e.g., hospital physician, general practitioner, psychiatrist, paediatrician). Results There were two main novel findings. First, we found that the proportion of patients with AP prescriptions was nearly ten times higher in low-income families than in the general population: 35.9% of CMU-C patients compared to 3.7% in all of Pays de la Loire (X 2 = 7875.1, p < 0.001). Additionally, we found a higher rate of FGAP than SGAP prescriptions (65% vs. 57%). Conclusions Our study suggests two types of AP misuse that could provide interesting targets for public healthcare interventions. First, our results strongly suggest an over-representation of patients from low-income families. Low-income families primarily resided in areas with low physician density and appeared to receive drugs to treat their conditions more frequently than other individuals. This increased prescription rate is a public health issue, potentially requiring political action. Second, the use of FGAPs did not adhere to the latest recommendations for drug use in this ...

International audience ; Recent studies analysing the trends in antipsychotic (AP) prescriptions for children and adolescents have raised concerns regarding the influence of socioeconomic status. Previous findings have also shown variable prescription rates for first-generation (FG) and second-generation (SG) APs. Method Our objectives were to assess the proportion of patients from low-income families receiving APs and the most commonly prescribed APs in France. We conducted a descriptive analysis of AP drugs dispensed during a 1-year period (July 1, 2013–June 30, 2014) in a northwestern region of France with 941,857 subjects less than 18 years old. All data were extracted from an exhaustive, individual and anonymous social security database. We obtained each subject's socioeconomic status (by identifying their affiliation with a specific social security program) and also collected sociodemographic data, drug type, prescribing and dispensing dates and amount, and prescriber type (e.g., hospital physician, general practitioner, psychiatrist, paediatrician). Results There were two main novel findings. First, we found that the proportion of patients with AP prescriptions was nearly ten times higher in low-income families than in the general population: 35.9% of CMU-C patients compared to 3.7% in all of Pays de la Loire (X 2 = 7875.1, p < 0.001). Additionally, we found a higher rate of FGAP than SGAP prescriptions (65% vs. 57%). Conclusions Our study suggests two types of AP misuse that could provide interesting targets for public healthcare interventions. First, our results strongly suggest an over-representation of patients from low-income families. Low-income families primarily resided in areas with low physician density and appeared to receive drugs to treat their conditions more frequently than other individuals. This increased prescription rate is a public health issue, potentially requiring political action. Second, the use of FGAPs did not adhere to the latest recommendations for drug use in this ...

Objectifs :Comparer la consommation de substances, les comportements de jeu et les traits de personnalité de deux groupes d'individus ayant un trouble de jeu pathologique (patients jeunes et adultes) ; explorer l'apport du sexe, de l'âge et des traits de personnalités sur la consommation de substances et évaluer la capacité de prédire la consommation de substances à partir de l'âge et des traits de personnalité.Méthodes :L'échantillon était formé de 428 patients ayant un trouble de jeu pathologique (TJP), divisés en deux groupes selon l'âge (55 jeunes patients [âge ≤ 25 ans] et 373 patients d'âge moyen à avancé [âge > 25 ans]). Tous les patients ont été admis dans un département de psychiatrie et diagnostiqués selon les critères du DSM-IV. En outre, d'autres évaluations cliniques, dont leDiagnostic Questionnaire for Pathological Gamblingen vertu des critères du DSM-IV, leSouth Oaks Gambling Screen(SOGS) et leTemperament and Character Inventory-Revised(TCI-R), ont été utilisées pour examiner les comportements de jeu, la consommation de substances et la personnalité.Résultats :À la comparaison des deux groupes d'âge, nous avons observé des différences statistiquement significatives pour plusieurs variables sociodémographiques. En outre, les plus jeunes patients ayant un TJP présentaient un taux plus élevé de consommation de substances (p = 0,010). Pour ce qui est des traits de personnalité, des différences ont été remarquées seulement à l'échelle de recherche de nouveautés (RN) où les patients plus jeunes obtenaient des cotes élevées (p= 0,006). Des cotes plus élevées (p=0,022) à l'échelle de recherche de nouveautés (RN) et plus basses (p= 0,028) à l'échelle d'auto-transcendance représentaient des traits de personnalité ayant une interrelation significative avec la consommation de tabac (p= 0,003). Toutefois, seul l'âge était associé à la consommation d'autres substances (p=0,003).Conclusions :Les résultats confirment que le trouble de jeu pathologique (TJP) est souvent concomitant avec la consommation de substances. L'interrelation du TJP et de la consommation de tabac, d'alcool et d'autres substances entraîne une gamme d'implications cliniques et liées à la personnalité, particulièrement chez les populations jeunes. Puisque plusieurs études ont démontré que le taux de TJP est plus élevé chez les jeunes, le début précoce du trouble est souvent lié à une gravité accrue et à une persistance des problèmes de jeu. En outre, la présence d'un double diagnostic (consommation de substances) pourrait compliquer la réponse aux traitements. Pour cette raison, l'étude des populations jeunes est d'un intérêt particulier afin de concevoir et de mettre en oeuvre des programmes de traitement qui abordent tous les problèmes liés aux profils cliniques de ce groupe d'âge.