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What Drives Violent Extremism in East Africa and How Should Development Actors Respond?
In: African security, Band 11, Heft 2, S. 160-180
ISSN: 1939-2214
What drives violent extremism in East Africa and how should development actors respond?
In: African security, Band 11, Heft 2, S. 160-180
ISSN: 1939-2206
World Affairs Online
RETRACTED ARTICLE: A biblical view of eating and nutrition in contrast to that in Graeco-Roman writings: restraint, respect, purpose, and order
In: Israel affairs, Band 25, Heft 5, S. I-XX
ISSN: 1743-9086
Identifying key components of a web‐based long term care planning intervention for family caregivers of individuals with intellectual/developmental disabilities
In: Journal of applied research in intellectual disabilities: JARID, Band 35, Heft 3, S. 867-877
ISSN: 1468-3148
AbstractBackgroundFew family caregivers of individuals with intellectual or developmental disabilities develop long‐term care (LTC) plans for their relative. Web‐based interventions promoting LTC planning have potential for widespread adoption into clinical practice.MethodsWe conducted focus groups with 49 primary caregivers of individuals with intellectual or developmental disabilities in NY, PA, OH, DE, and TX to identify barriers and facilitators of LTC planning, review existing tools, and identify critical features for web‐based LTC planning interventions. Participants also answered questions on demographic characteristics and functional status.ResultsNVivo qualitative analysis software was used to analyse focus groups using a grounded theory approach. Caregivers identified web tool accessibility and topics such as finances, housing, and government benefits as critical. Caregivers also described desired features for a LTC planning tool.ConclusionsThis study identified desired characteristics of web‐based LTC planning tools and ways in which existing web‐based interventions might be adapted or enhanced.
Psychosocial and Cultural Determinants of Interest and Uptake of Skin Cancer Genetic Testing in Diverse Primary Care
In: Public health genomics, Band 22, Heft 1-2, S. 58-68
ISSN: 1662-8063
<b><i>Background:</i></b> Translational research in genomics has limited reach and requires efforts to broaden access and utility in diverse populations. Skin cancer is common and rates are rising, including among Hispanics. Germline variants in the melanocortin-1 receptor (<i>MC1R</i>) gene are common in the population and confer moderate risk for melanoma and basal cell cancers across skin types. Feedback about <i>MC1R</i> risk status may promote skin cancer risk awareness and risk reduction. <b><i>Aims:</i></b> We examined the level of interest in pursuing <i>MC1R</i> testing, and patterns of interest across skin cancer perceived threat and control attitudes, cultural beliefs (family influence on health, health system distrust, cancer fatalism, skin cancer misconceptions), and health literacy. <b><i>Methods:</i></b> We used a study website to inform primary care patients in Albuquerque, NM about the benefits and drawbacks of <i>MC1R</i> testing. Website logon, request of a saliva test kit, and return of the test kit (yes vs. no) were primary assessments of study interest and uptake. <b><i>Results:</i></b> Of 499 participants provided with a test offer, 33% requested and returned the test. Lower family influence on participants' health was an important factor both overall and within ethnicity subgroups, and may indicate that primary care patients interested in skin cancer genetic testing see themselves as proactive health seekers, independent from family encouragement. Lower self-efficacy for skin cancer prevention was also an important characteristic of those who tested. <b><i>Conclusion:</i></b> As evidence for common genetic markers for skin cancer accumulates, these findings suggest characteristics of those most likely to pursue genetic testing for skin cancer risk.
Poor Oral Health Is Associated With Inflammation, Aortic Valve Calcification, and Brain Volume Among Forager-Farmers
In: The journals of gerontology. Series A, Biological sciences, medical sciences, Band 79, Heft 5
ISSN: 1758-535X
Abstract
Poor oral health is associated with cardiovascular disease and dementia. Potential pathways include sepsis from oral bacteria, systemic inflammation, and nutritional deficiencies. However, in post-industrialized populations, links between oral health and chronic disease may be confounded because the lower socioeconomic exposome (poor diet, pollution, and low physical activity) often entails insufficient dental care. We assessed tooth loss, caries, and damaged teeth, in relation to cardiovascular and brain aging among the Tsimane, a subsistence population living a relatively traditional forager-horticulturalist lifestyle with poor dental health, but minimal cardiovascular disease and dementia. Dental health was assessed by a physician in 739 participants aged 40–92 years with cardiac and brain health measured by chest computed tomography (CT; n = 728) and brain CT (n = 605). A subset of 356 individuals aged 60+ were also assessed for dementia and mild cognitive impairment (n = 33 impaired). Tooth loss was highly prevalent, with 2.2 teeth lost per decade and a 2-fold greater loss in women. The number of teeth with exposed pulp was associated with higher inflammation, as measured by cytokine levels and white blood cell counts, and lower body mass index. Coronary artery calcium and thoracic aortic calcium were not associated with tooth loss or damaged teeth. However, aortic valve calcification and brain tissue loss were higher in those who had more teeth with exposed pulp. Overall, these results suggest that dental health is associated with indicators of chronic diseases in the absence of typical confounds, even in a population with low cardiovascular and dementia risk factors.