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INTRODUCTION: WHO's International Clinical Trials Registry Platform (ICTRP) has 17 primary registries that collect the information on the minimum set of items of trial information that appear in the register and these registries are also endorsed by the International Committee of Medical Journal Editors. OBJECTIVE: The objective of this study is to describe the profile of all the primary registries including Clinical Trial Registry‑India (CTRI), through features such as magnitude, domain of registration, flagging, audit trail, language, mandatory requirements, and result disclosure. METHODOLOGY: The profiling of all registries was based on countries and zones, year of establishment, registrant, flagging, conflict of interest, language, documents, result disclosure, type of study, mode of registration, mandate of registration, quality check method, individual patient data statement and translation of content facility. The mode of search used was online which included advanced search, basic search and also from the audio/video manual on their website. RESULTS: There are 17 primary registries of ICTRP, the first one International Standard Randomised Controlled Trial Number (ISRCTN) of England being initiated in year 2000 and the most recent being Lebanese registry, in September 2019. The trials registered with these registries range from 301 in Cuba to 53972 in European union's EU Clinical Trials Register. The primary registries in WHO registry network are diverse in functionalities and practices. The characteristics of online registers vary in content and features and to achieve coordinated level of data quality, across all the different registries and to keep a balance in standards of the data collected and validation of that data, the registries are adhering to the minimum data set items laid down by ICTRP. CONCLUSION: The very process of registering the clinical studies helps in promoting the research methods and also raising the standards of research, especially among young researchers. It also helps in ...

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. ; A stellar occultation by Pluto was observed on 2020 June 6 with the 1.3 m and 3.6 m telescopes located at Devasthal, Nainital, India, using imaging systems in the I and H bands, respectively. From this event, we derive a surface pressure for Pluto's atmosphere of psurf=12.23-0.38+0.65 μbar. This shows that Pluto's atmosphere has been in a plateau phase since mid-2015, a result which is in excellent agreement with the Pluto volatile transport model of Meza et al. This value does not support the pressure decrease reported by independent teams, based on occultations observed in 2018 and 2019 by Young et al. and Arimatsu et al., respectively. © 2021. The Author(s). Published by the American Astronomical Society. ; The authors are grateful to the Directors of ARIES and IIA for granting time under Directors' Discretionary Time allotment for observing this event. The authors also thank the staff of the Devasthal Observatory and the IR Group at TIFR for their help during observations. The work leading to these results has received funding from the European Research Council under the European Community's H2020 2014-2021 ERC Grant Agreement no. 669416 "Lucky Star." Research at PRL and IIST is supported by the Department of Space, Government of India. M.A., G.B.-R., F.B.-R., and R.V.-M. thank CNPq and CAPES for grants 313144/2020-6, 314772/2020-0, 465376/2014-2, and Process 88887.310463/2018-00—Project 88887.571156/2020-00. R.V.-M. also thanks grant CNPq 304544/2017-6. P.S-S. acknowledges financial support by the Spanish grant AYA-RTI2018-098657-J-I00 "LEO-SBNAF" (MCIU/AEI/FEDER, UE). ; With funding from the Spanish government through the Severo Ochoa Centre of Excellence accreditation SEV-2017-0709. ; Peer reviewed