Suchergebnisse

AbstractAIMSTo synthesize the oral alterations observed in children with microcephaly associated with congenital Zika virus syndrome (CZS), and to compare the oral alterations of these children to a normotypic healthy controls.METHODS AND RESULTSA search was performed in six electronic databases. Observational studies published that reported oral alterations in children with CZS were selected. Two authors independently extracted data, assessed study quality, using the Joanna Briggs Institute Critical Appraisal Checklist tools, and the certainty of evidence, using Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Twenty‐one studies were included in this systematic review and meta‐analysis. The pooled crude occurrence showed 88% of increased salivation (95%CI: 82%–94%), 83% of biofilm (95%CI: 75%–91%), and 73% of bruxism (95%CI: 52%–95%). Compared to normotypic controls, children with CZS‐associated microcephaly had a higher chance to have difficulty in lip sealing (OR: 18.28; 95%CI: 1.42–235.91), inadequate lingual posture at rest (OR: 13.57; 95%CI: 4.24–43.44), and delayed eruption (OR: 12.92; 95%CI: 3.42–48.78), with very low certainty.CONCLUSIONThere are several oral alterations found among children with CZS‐associated microcephaly. They are more prone to present some of these alterations, such as difficulty in lip sealing, although with very low certainty of evidence.

AbstractMyiasis is an infection caused by the deposition of fly larvae in tissues, and its involvement in the human oral cavity is uncommon. Herein, we have performed a data analysis of published cases of oral myiasis. A search was performed in PubMed, Ovid, Web of Science, Scopus, and LILACS. Geographic distribution, demographic data, associated factors, clinical features, fly types, treatment, and presence of sequelae were analyzed. A total of 122 articles reported the cases of 157 infected individuals. The most affected countries were India (41%) and Brazil (29.5%). Male predominance (67.5%) and a mean of 41.9 years of age were observed. The gingiva (29%) was the most affected site, followed by palate (25%) and lip (21%). There were different forms and combinations of treatments: manual removal of larvae and surgical debridement, application of asphyxiating substances, antibiotic therapy, and use of ivermectin. The condition predominantly affects individuals with neurological and/or locomotor disabilities, of low socioeconomic status, with poor oral hygiene and chemical dependence and individuals with previous injuries or with the absence of lip sealing. The establishment of a standard treatment protocol, enabling comparison in future studies and providing uniformity in treatment strategies offered by health services is strongly recommended.