Suchergebnisse

Angola reports one of the highest infant mortality rates in the world, and anemia represents one of its important causes. Recent studies, in under-five children from the Bengo province of Angola, described high prevalence's, suggesting malaria, undernutrition and urogenital schistosomiasis as important contributors for the occurrence and spatial variations of anemia. Educational community-based interventions, either in Nutrition and Water, Sanitation, Hygiene and Malaria are recommended to correct anemia. Herein, we designed a cluster-randomized controlled trial to study the efficacy of two educational-plus-therapeutic interventions in the reduction of anemia: one in nutrition and the other in WASH/Malaria. Socioeconomic, nutritional, anthropometric, parasitological and biochemical data will be collected from all willing-to-participate children, aging under four and resident in the Health Research Center of Angola study area. Considering the multifactorial causes of this condition, determining the efficacy of both interventions might help documenting weaknesses and opportunities for planning integrated strategies to reduce anemia. ; The promoters of CISA providing financial support for this study are as follows: Camões, Institute of Cooperation and Language, Portugal; Calouste Gulbenkian Foundation, Portugal; Government of Bengo Province; Angolan Ministry of Health. Additionally, this investigation also receives financial support from TDR, The Special Programmed for Research and Training in Tropical Diseases, co-sponsored by UNICEF, UNDP, the World Bank and WHO (for molecular analyses) and from Bank Foment of Angola (for determining the serum micronutrient levels). Representing the Angolan Ministry of Health, the National Malaria Control Program and the National Neglected Tropical Diseases Control Program agreed to provide rapid malaria diagnostic tests, mosquito bed nets, antimalarial drugs and also drugs for intestinal parasites and schistosomiasis for this study. At the local level, the General Hospital of Bengo will provide the facilities for biochemical analysis and facilities for consultations, and will also receive and manage the pediatric emergency cases referred by the study's field nurses. Furthermore, the David Bernardino Paediatric Hospital agreed to provide the Molecular Biology Laboratory for the molecular analyses. ; info:eu-repo/semantics/publishedVersion