Suchergebnisse

This was a record-linkage analysis of a birth cohort to examine the association between self-reported self-harm in adulthood and childhood maltreatment (CM) as prospectively notified to authorities and self-reported on the Child Trauma Questionnaire. There were 2507 participants at 30-year follow-up with data on both CM and self-reported self-harm including an intent to die. Of the participants, 304 (12.1%) had self-harmed at some time in their lives while 150 (4.2%) had wanted to die. The prevalence of self- and agency-reported maltreatment was 513 (20.5%) and 143 (5.7%) respectively. On adjusted analyses, CM irrespective of reporting source showed significant associations with both suicidal outcomes. Physical and emotional abuse showed the strongest associations while findings for neglect were mixed. The only association for sexual abuse was for self-reported maltreatment and intent to die but numbers may have been under-powered.

Child sexual abuse (CSA) has been associated with many adverse psychiatric outcomes. However, most studies have relied on retrospective self-report of exposure to CSA. We set out to investigate the incidence of CSA in the same birth cohort using both retrospective self-report and prospective government agency notification, and examine the psychological outcomes in young adulthood. The primary outcomes were measures of DSM-IV diagnoses (CIDI-Auto) at age 21. The 21-year retrospective CSA questions were completed by 3739 participants. CSA was self-reported by 19.3% of males and 30.6% of females. After adjustment for potential confounders, both self-reported and agency-notified CSA were associated with increased odds of lifetime major depressive disorder (MDD), anxiety disorders, and posttraumatic stress disorder (PTSD). For the first time in a birth cohort, this study has shown the disparity between the incidence of CSA when measured by self-report and government agency notification. Despite this discrepancy, adverse psychiatric outcomes are seen when CSA is defined using either method.

This study investigates the association between exposure to prospectively-substantiated childhood maltreatment between 0 to 14 years of age and lifetime cannabis use, abuse and dependence reported at 21 years. Data were taken from 2526 (51.6% female) participants in the Mater Hospital-University of Queensland Study of Pregnancy, a pre-birth, prospective, cohort study. Prospectively-substantiated cases of childhood maltreatment, reported to the government child protection agencies between 0 and 14 years of age, were linked to CIDI DSM-IV self-report data from the 21-year follow-up. Exposure to any childhood maltreatment, and childhood neglect in particular, predicted subsequent cannabis abuse with adjusted odds ratios (AORs) of 1.79 and 2.62, respectively. Any childhood maltreatment, physical abuse, emotional abuse and neglect predicted cannabis dependence with AORs of 2.47, 2.81, 2.44 and 2.68, respectively. The associations for an early age of onset of cannabis abuse and dependence were significant and consistent for maltreated children. In addition, frequency of maltreatment substantiations predicted cannabis abuse, dependence and an early age of onset of these disorders. The AORs for cannabis ever use without any DSM-IV cannabis disorder were 1.78 for any maltreatment and 2.15 for emotional abuse. Any childhood maltreatment and neglect predicted lifetime ever cannabis use, as well as cannabis use disorder. There was little evidence for any interaction between gender and different forms of childhood maltreatment and its association with cannabis use disorders. Physical abuse, emotional abuse and neglect, as well as multiple episodes of maltreatment independently predicted cannabis use disorders.