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"How human technological interventions into death and the dead body since the nineteenth century have had a profound impact on today's (and future) end-of-life and human mortality realities. As Director of the Centre for Death and Society, the world's only interdisciplinary studies centre dedicated to researching death, dying, and the dead body, and the son of an American Funeral Director who grew up in the funeral industry, I am uniquely positioned to author a new book on the human corpse and technology. Death and the dead body are both extremely popular topics, and the books being currently published are tapping into that popular appeal. Most of these books, however, cover topics that remain perennially discussed. Indeed, it is striking how so many of the current books on death and dying reflect the same issues raised during the 1970's, a decade during which Publisher's Weekly enthusiastically told its readers "Death is now selling books!" A quick snapshot of some current(ish) death, dying, and dead body books includes, but is certainly not limited to: Mary Roach's Stiff: The Curious Lives of Human Cadavers, which was published in 2003 but remains widely read thirteen-years later; more recent books, such as Atul Gawande's Being Mortal, Caitlin Doughty's Smoke Gets in Your Eyes, and Brandy Schillace's Death's Summer Coat have all tapped into this popular genre. Books by academic authors such as Margaret Schwartz's Dead Matter and Thomas Laqueur's The Work of the Dead present historical and cultural contexts that are equally important. My listing of texts could exceed several pages but what is important about most contemporary death books is that the texts rarely give the history of publishing books on death much analysis. If any death-topic authors' names appear they are usually Jessica Mitford, Elizabeth Kübler-Ross, and Ernest Becker. Sigmund Freud sometimes appears (in connection to Becker) but on the whole these specific authors represent a fraction of the 'death canon.' What I am writing improves on these texts by presenting readers with a more complex and interesting history than most books on death, dying, and the dead body currently pursue. In a nutshell I present a longer view on how human technological interventions into death and the dead body since the nineteenth century have had a profound impact on today's (and future) end-of-life and human mortality realities. It is too easy to sum up most current books on death, dying, and the dead body ...

"How human technological interventions into death and the dead body since the nineteenth century have had a profound impact on today's (and future) end-of-life and human mortality realities. As Director of the Centre for Death and Society, the world's only interdisciplinary studies centre dedicated to researching death, dying, and the dead body, and the son of an American Funeral Director who grew up in the funeral industry, I am uniquely positioned to author a new book on the human corpse and technology. Death and the dead body are both extremely popular topics, and the books being currently published are tapping into that popular appeal. Most of these books, however, cover topics that remain perennially discussed. Indeed, it is striking how so many of the current books on death and dying reflect the same issues raised during the 1970's, a decade during which Publisher's Weekly enthusiastically told its readers "Death is now selling books!" A quick snapshot of some current(ish) death, dying, and dead body books includes, but is certainly not limited to: Mary Roach's Stiff: The Curious Lives of Human Cadavers, which was published in 2003 but remains widely read thirteen-years later; more recent books, such as Atul Gawande's Being Mortal, Caitlin Doughty's Smoke Gets in Your Eyes, and Brandy Schillace's Death's Summer Coat have all tapped into this popular genre. Books by academic authors such as Margaret Schwartz's Dead Matter and Thomas Laqueur's The Work of the Dead present historical and cultural contexts that are equally important. My listing of texts could exceed several pages but what is important about most contemporary death books is that the texts rarely give the history of publishing books on death much analysis. If any death-topic authors' names appear they are usually Jessica Mitford, Elizabeth Kübler-Ross, and Ernest Becker. Sigmund Freud sometimes appears (in connection to Becker) but on the whole these specific authors represent a fraction of the 'death canon.' What I am writing improves on these texts by presenting readers with a more complex and interesting history than most books on death, dying, and the dead body currently pursue. In a nutshell I present a longer view on how human technological interventions into death and the dead body since the nineteenth century have had a profound impact on today's (and future) end-of-life and human mortality realities. It is too easy to sum up most current books on death, dying, and the dead body by simply saying, "We've been here before" - but it's also accurate. What my book presents are new and important ways to critically understand both the distant and recent past of human death, e.g., nineteenth century postmortem photography's crucial relationship to twentieth century life extension technology. Ironically, these nineteenth century historical records are often archived and accessible (and very well presented in MIT Press's Secure the Shadow by Jay Ruby), whereas web based material from twenty, even ten-years-ago often disappears before it can be analyzed and discussed. The key point for any book being written about death and dying today is that it really needs to understand and articulate how popular interest in death didn't emerge from nowhere. The current popularity of death, dying, and the dead body is the result of many individuals working in many different fields over the last two centuries as both academics and practitioners. More than anything the collective twenty-first century discourse on death needs to have its dominant narratives challenged and pushed in new directions. This book takes on that challenge and re-defines death, dying, and the dead body for readers by opening up human mortality's complicated and often vexing history"--

The different countries that death and dying researchers reside within often shape not only research agendas but also research methodologies. The United Kingdom and the United States are two examples of countries that share a common language and intellectual history but their discourses on death have been very different. These differences are partly explained through cultural practices, and also government funding of research, definitions of death and end-of-life planning education. In this article, we argue that early death scholarship in the United States impacted death research and outcomes in both the US and the UK, but that recent scholarship in both countries has caused the two countries to diverge in two major areas: (1) the methodological approaches to death studies and (2) the educational training of medical and hospice personnel in direct contact with the dying. We argue that in order for death studies to fully benefit from trans-Atlantic dialogue on death, both countries need to move towards a more integrated trans-disciplinary model.

Poisoning by nerve agents via the percutaneous (p.c.) route is an issue because the slow absorption of agent could result in poisoning which outlasts the protection provided by conventional pharmacological therapy. The bioscavenger approach is based on the concept of binding nerve agent in the bloodstream, thus preventing nerve agent from reaching the target tissues and inhibiting acetylcholinesterase activity. One bioscavenger that has been extensively studied is human butyrylcholinesterase (huBuChE). Protexia® is a pegylated form of recombinant huBuChE. We used a guinea-pig model of p.c. nerve agent poisoning, using an implanted telemetry system to collect physiological data. Guinea-pigs were poisoned with the nerve agent VX (0.74 mg/kg) (~2.5×LD50). Two hours following VX exposure, Protexia (72 mg/kg) or saline control was administered intramuscularly. All guinea-pigs treated with Protexia (n=8) survived, compared to no survivors in a saline-treated control group (n=8). Survival following VX and Protexia treatment was associated with minimal incapacitation and observable signs of poisoning, and the mitigation or prevention of the detrimental physiological changes (e.g. seizure, bradycardia and hypothermia) observed in control animals. The opportunity for post-exposure treatment may have utility in both civilian and military scenarios, and this is a promising indication for the use of a bioscavenger.