Suchergebnisse

Contends, contrary to some media portrayals of the Internet as a surfer's playground without signposts, that the Internet does offer some direction to serious researchers seeking operations and production management information. Attempts to decipher the Internet as a medium for information gathering and to explain how it may be used as a resource for those in the operations management field. Aims to assist the Internet novice to find his or her point of embarkation and to introduce the more experienced user to new sources of useful data. Considers how the Internet may be used to promote the operations and production management discipline, and suggests ways in which both academics and practising managers may participate and so benefit.

Cover -- Title Page -- Copyright -- Dedication -- Contents -- List of Figures -- List of Tables -- Preface and Acknowledgments -- 1. Disasters as Political Challenges -- 2. Florida Legislators: Locally Elected State Officials -- 3. The Kaleidoscope of Florida Politics -- 4. Executive Branch Effects? -- 5. Andrew's First Cavalry: State Officials Respond -- 6. In the Eye: Incumbents from Severely Damaged Cities -- 7. On the Edge: Incumbents from Less Severely Damaged Cities -- 8. Out of the Eye: Incumbents from the Least Severely Damaged Cities -- 9. Disasters as Political Challenges and Opportunities -- Appendix: Methodology -- Bibliography -- Index

An examination of the politics of disaster on the local level through the analysis of three levels of incumbent politicians in the aftermath of Hurricane Andrew in South Florida.

Companies are increasingly adopting technologies that can promote
integration between functions and tasks. The implementation of these
technologies has largely concerned the tasks of installation and the
technical integration of the system. However, insufficient attention
appears to have been directed towards organizational and managerial
integration issues. Argues, based on empirical data from 15 UK
engineering companies, that effective implementation of integrating
technology requires a better understanding of issues concerning the
integration of functions/tasks involved. Focuses on the issues and
problems concerning managers involved with improving
engineering/production integration, and proposes alternative
organizational and technical mechanisms for implementing such
integration. Reviews these mechanisms by reference to the engineering
case companies.

Flavonoids are a large family of compounds associated with a broad range of biologically useful properties. In recent years, synthetic compounds that contain two flavonoid units linked together have attracted attention in drug discovery and development projects. Numerous flavonoid dimer systems, incorporating a range of monomers attached via different linkers, have been reported to exhibit interesting bioactivities. From a medicinal chemistry perspective, the 1,2,3-triazole ring system has been identified as a particularly attractive linker moiety in dimeric derivatives (owing to several favourable attributes including proven biological relevance and metabolic stability) and triazole-bridged flavonoid dimers possessing anticancer and antimalarial activities have recently been reported. However, there are relatively few examples of libraries of triazole-bridged flavonoid dimers and the diversity of flavonoid subunits present within these is typically limited. Thus, this compound type arguably remains underexplored within drug discovery. Herein, we report a modular strategy for the synthesis of novel and biologically interesting triazole-bridged flavonoid heterodimers and also very rare heterotrimers from readily available starting materials. Application of this strategy has enabled step-efficient and systematic access to a library of structurally diverse compounds of this sort, with a variety of monomer units belonging to six different structural subclasses of flavonoid successfully incorporated. ; Cambridge Commonwealth Trust, European Research Council under the European Union's Seventh Framework Programme (FP7/2007–2013)/ERC grant agreement No. [279337/DOS], AstraZeneca, European Union, Engineering and Physical Sciences Research Council, Biotechnology and Biological Sciences Research Council, Medical Research Council, Wellcome Trust

[EN] The impact of national legislative frameworks on the higher education sector's contribution to technological innovation is heavily disputed. This paper argues that legislative frameworks may stimulate the development of local practices for the management and exploitation of intellectual property (IP), which in turn determine the level of academic patenting. We present case studies of two comparable universities in each of four selected European countries with different histories of national IP legislation. A within-country analysis shows that a wider range and earlier development of local IP management and exploitation practices are accompanied by higher levels of academic patenting, and that increasing similarity of IP practices is associated with decreasing differences in patenting outputs. A preliminary cross-country analysis reveals an expansion in and increasing similarity of practices for IP management and exploitation in countries with different national IP framework histories.We conclude that adopting Bayh-Dole-like legislation may trigger the development of local IP practices, which stimulate patenting. However, it is not always sufficient and definitely not always necessary. The study concludes with some policy recommendations. ; Part of this research was supported by the European Patent Office. Funding is gratefully acknowledged. ; Weckowska, DM.; Molas-Gallart, J.; Tang, P.; Twigg, D.; Castro-Martínez, E.; Kijenska Dabrowska, I.; Libaers, D. (2018). University patenting and technology commercialization legal frameworks and the importance of local practice. R and D Management. 48(1):88-108. https://doi.org/10.1111/radm.12123 ; S ; 88 ; 108 ; 48 ; 1