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The International Postgraduate Course on Flood Management in the Dan- ube River Basin is aimed at harmonizing the necessary levels of education, information and preparedness prior to declaring a food on the Danube as a widest-scale phenomenon under the EU Strategy for the Danube Region. A further intention is a timely exchange of experience and knowledge and a better coordination of competent institutions immediately before a food occurrence and for the duration of high waters and foods on the Danube and its tributaries as a basis of an integrated system of harmonized cross-border management. The goal is adequate preparation and higher mutual harmonization during foods as well as cross-border assistance in order to establish a sustainable system for protecting human life and property in the entire Danube River Basin. Based on the analysis of historical data on the Danube foods, hydrological and hydraulic considerations and risk models, including the aspects of food ccurrences and food forecasting, food-related legislation and regulations are presented. Finally, an overview of possible models, measures of food protection and impacts on the infrastructure of river and urban systems is provided for the purpose of impact assessment on the environment as well as climate change impact on foods in the Danube river basin.

PMCID: PMC3539432; NIHMSID: NIHMS430346.-- et al. ; A first research development progress report of the Chromosome 19 Consortium with members from Sweden, Norway, Spain, United States, China and India, a part of the Chromosome-centric Human Proteome Project (C-HPP) global initiative, is presented (http://www.c-hpp.org). From the chromosome 19 peptide-targeted library constituting 6159 peptides, a pilot study was conducted using a subset with 125 isotope-labeled peptides. We applied an annotation strategy with triple quadrupole, ESI-Qtrap, and MALDI mass spectrometry platforms, comparing the quality of data within and in between these instrumental set-ups. LC-MS conditions were outlined by multiplex assay developments, followed by MRM assay developments. SRM was applied to biobank samples, quantifying kallikrein 3 (prostate specific antigen) in plasma from prostate cancer patients. The antibody production has been initiated for more than 1200 genes from the entire chromosome 19, and the progress developments are presented. We developed a dedicated transcript microarray to serve as the mRNA identifier by screening cancer cell lines. NAPPA protein arrays were built to align with the transcript data with the Chromosome 19 NAPPA chip, dedicated to 90 proteins, as the first development delivery. We have introduced an IT-infrastructure utilizing a LIMS system that serves as the key interface for the research teams to share and explore data generated within the project. The cross-site data repository will form the basis for sample processing, including biological samples as well as patient samples from national Biobanks. © 2012 American Chemical Society. ; This work was supported by grants from the Swedish Academy of Pharmaceutical Sciences who is the core founder our consortium, Swedish Research Council, the Swedish Foundation for Strategic Research, Vinnova, Ingabritt & Arne Lundbergs forskningsstiftelse, the Crafoord Foundation and by Thermo Fisher Scientific for mass spectrometry instrument support. T.E.F. is supported by the Mobilitas Program sponsored by the European Union Social Fund and administered by the Estonian Science Foundation. We gratefully acknowledge financial support to M.F. from Health Institute Carlos III of Spain (ISCIII, FIS PI02114) and M.G.-G. is supported by a PhD scholarship of ISCIII FI08/00721. C.L.N. is supported by the Cancer Prevention and Research Institute of Texas and the University of Texas Medical Branch. [11-0624]; National Cancer Institute [R33 CA 127768-03, R01CA160816, and P50-CA92629]; Sidney Kimmel Center for Prostate and Urologic Cancers; and David H. Koch through the Prostate Cancer Foundation. ; Peer Reviewed

One of the main threats of our time is the increasing water demand not only globally, but also locally. These are often met at the expense of ecological water demand, jeopardizing the structural and operational conditions necessary to maintain good ecological status in aquatic and wetland habitats. This is why it is of great importance to explore possible water retention options. In 2019, based on the long-term data series on the water level of River Tisza, we studied the frequency and extent of flooding in the floodplain between Tiszabercel and Gávavencsellő, where there are valuable wetlands, including a 'sanctuary'-type backwater. This was necessary because recently the floodplains have undergone negative changes. Their water volume has gradually decreased, their valuable wildlife has become rarer, some of them have completely dried out in the autumn and even one of them has burned out. From the analysis of the examined 48-years data, it could be concluded that flooding was relatively frequent in the sampled area, but the extent of water coverage had no significant effect either in space or time. It was also found that only water levels above 700 cm (based on the water meter of Tiszabercel, 98.36 mBf) could adequately ensure that the water bodies are filled up and flushed out. However, there is little chance of this, because of four reasons: (1) water levels of this height are becoming rare; (2) the duration and height of high water levels are mostly short in time; (3) water levels of several water bodies are artificially decreased; (4) the drainage effect of the River Tisza – which has been significantly incised after the river regulation – prevails in the area. Due to all, in the future, there would be a great need to maintain the water levels in the floodplain wetlands as efficiently as possible after the floods – for which we have made specific proposals for the places and methods to preserve the ecologically necessary amount of water.