APPROPRIATENESS OF PROTON PUMP INHIBITOR USE IN A PSYCHOGERIATRIC POPULATION
Inappropriate medication use is the use of a medication where the potential risks associated with use outweigh the potential benefits. Inappropriate medication use among older people is known to contribute to adverse health outcomes including hospitalisation and death. Proton pump inhibitors (PPIs) are medications which are commonly used to treat gastric-acid related disorders. Long-term use of PPIs has been associated with several risks including Clostridium Difficile infection, pneumonia, kidney disease and potentially dementia. Inappropriate PPI use is common in older people with up to 80% of patients using a PPI inappropriately. This study explored the appropriateness of PPI prescribing in an inpatient psychogeriatric population which is a vulnerable and understudied patient cohort. Pilot data obtained from 67 inpatients showed that 33% of patients were using a PPI at the time of admission. PPI use was found to be potentially inappropriate in 68% of cases. Un-investigated GORD was the most commonly identified inappropriate indication with 41% of patients using a PPI for this reason. The average frailty score was increased by 10% and the Katz index for independence in activities of daily living was reduced by 15% in PPI users compared to non-users. Both nationally and internationally, PPIs are listed as the most commonly prescribed medications and the costs to the government and the individual are significant. This study demonstrates that there is an opportunity to deprescribe PPIs in psychogeriatric patients which would not only reduce the risk of adverse health outcomes but also result in significant cost saving.