The myth that women had equal rights and were emancipated in the Soviet Union masks the reality that the Soviet state, like all totalitarian states, is a manifestation of patriarchal ideology. The true democratization of Russian society requires the rejection of masculinist ideology and constitutes one of the most important social and cultural challenges.
In: Vestnik Permskogo universiteta: Perm University Herald. Seriya Filosofia Psikhologiya Sotsiologiya = Series "Philosophy, psychologie, sociology", Heft 1, S. 5-16
The purpose of this article is to analyze the evolution of the concept of gender in social knowledge and the humanities. The term «gender» encompasses biological (sexual), psychological, social, cultural, symbolic aspects of human life. Even before the introduction of this term into scientific publications in the 1960s, the phenomenon itself was discovered in three types of knowledge: in psychology and psychiatry when studying various forms of sexuality and sexual identity, in anthropological and ethnographic studies, and in the feminist philosophy of culture. This largely determined the main directions in the study and understanding of gender for several decades. The theory of socio-cultural construction of gender played the main role. It developed in parallel with other critical and constructivist scientific concepts, which in no small part led to its adoption by «academics» and the inclusion of the gender perspective in the body of scientific research. However, along with the development of postmodern feminist philosophy, the concept of gender undergoes redefinition. The constructivist model of gender is displaced by the performative concept of Judith Butler. She argues that not only gender but the biological sex does not exist outside the cultural framework and power discourse. The binary matrix of gender, gender identity and heterosexuality is approved within the framework of the dominant discourse with the help of various regulatory actions (performatives). Butler rejects this model because she claims that bodies, sex and gender identity have different configurations. The performative concept of sex was actively used in the queer project, as it provided justification for rejecting the normative binary concept of femininity and masculinity and the corresponding heterosexuality. Today, queer includes political movement, research, art, and discursive deconstruction of normative heterosexuality. The variant of mosaic nature, hybridity and relativism of identity proposed in the queer project destroys the possibility of social and political transformations in the sphere of gender equality. Instead, queer activists advocate an elusive equality of opportunity to try on different identities at one's own discretion. At the present stage, the theoretical radicalism of queer makes the development of new social programs unlikely, while they appear to be necessary. In contrast, gender theory (in its feminist, constructivist, and cultural-symbolic modes) has had a significant scientific and social impact. The use of the gender perspective in social knowledge and the humanities has provided better understanding of the individual and society. The principle of achieving gender equality has been accepted by the world community and has become part of many programs at the international and national levels. However, the problems in the understanding of the relation between sex and gender, discovered in performative and queer theory, become significant against a background of spreading biotechnologies (from sex reassignment surgeries to assisted reproduction). This requires wider research and further discussion among different schools.
For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale.
For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale. Analysis of clinicopathologic annotations for over 11,000 cancer patients in the TCGA program leads to the generation of TCGA Clinical Data Resource, which provides recommendations of clinical outcome endpoint usage for 33 cancer types.