Suchergebnisse

The Pastureland Rehabilitation Program (PRP) has been implemented for nearly 20 years, and the lives of herders in different regions have been affected to varying degrees. The level of people's well-being could measure the success of policy. Taking Maduo County as an example, the life satisfaction of 266 Tibetan herders was investigated through a participatory questionnaire survey in July 2021. Multiple linear regression and optimal scale regression were constructed to analyze the impact of the satisfaction of different aspects of life and PRP on life satisfaction, respectively. The results show that the herders in Maduo County had relative high satisfaction in various aspects of life and overall life, and leisure and consumption were important aspects influencing life satisfaction. The relative living standard, the difficulty in borrowing and the quality of government services had a significant positive impact on herders' life satisfaction. Occupation and migration location also led to the significant differences of life satisfaction. However, the income changes caused by PRP and subsidy levels did not show a significant impact. We discussed the particularity of Maduo County and suggested that more attention should be paid to the improvement of the social environment such as wealth disparity, channels of assistance, working environment, and the effective assistance formulated according to the demands of different groups needs to be optimized continuously, so as to enhance the self-development ability of herders.

The harm caused by defective vaccines to human health and social stability is immeasurable. Aiming at the government's supervision of the vaccine market, an evolutionary game model is constructed to analyze the quality of supervision and the key factors in the dynamic interaction between government departments and vaccine manufacturers under different supervision modes in the vaccine manufacturing process. The results show that: (1) Severe punishment by government regulatory authorities, and increased costs of rectification after investigation and handling of involuntary behaviors of vaccine enterprises can effectively prevent involuntary behaviors of vaccine enterprises. (2) In the early stage of the game, the success rate of the government's efficient supervision will make the vaccine enterprises continuously self-disciplined; when the vaccine market is relatively stable, the government's supervision departments tend to be more conducive to passive supervision. (3) The success rate of government regulatory departments and the probability of a third-party reporting to play a great role in promoting the self-discipline of enterprises. (4) The power of government and regulation are conducive to promoting the active supervision of the government regulatory authorities but corruption of government and awareness of people are different. Once the phenomenon of vaccine enterprises' non-discipline increases, the government regulation must change from passive regulation to active regulation. Therefore, the government should implement different measures according to the characteristics of each period in the manufacturing process to effectively prevent problematic vaccines. The conclusions and policy recommendations are significant for addressing the issue of insufficient self-discipline of vaccine manufacturers.

We investigate the possibility to maintain an electric polarization in an organic bilayer via ion trapping, i.e., without any external bias. In the cryptand-polyanion bilayer, ions of specific size can be strongly coordinated with organic macrocyclic molecules. Cations move from the polyanion layer to the cryptand layer upon applying a bias and are trapped in this layer. As a result, the voltage dependence of the polarization displays a hysteresis. The bilayer is then advantageously used as an electronic insulating layer in an organic field effect transistor. The ions trapping and de-trapping can be followed by the amplitude of the threshold voltage (V(th)) shift as well as its temporal evolution. ; Funding Agencies|Swedish Government||Swedish Foundation for Strategic Research||Brains and Bricks||Linkoping University||Knut and Alice Wallenberg Foundation||Onnesjo Foundation||

PurposeTo examine the strategic posture of third‐party logistics (3PLs) providers in mainland China.Design/methodology/approachA sample survey, obtained by mail, of 3PLs firms in mainland China. Key informant data are used to operationalize Porter's competitive strategy and provides a framework to identify logistics strategies pursued by 3PLs providers. Various aspects of 3PLs providers are compared by different strategy types.FindingsIdentified four logistics strategies pursued by 3PLs providers in mainland China. Differentiation strategy outperforms cost leadership strategy. Companies pursuing cost leadership are shifting towards differentiation strategy to cope with the intense competition faced in mainland China's immense logistics markets.Research limitations/implicationsBias may exist due to the mail survey. In‐depth studies on strategy formulation of 3PLs providers could be carried out to examine what factors influence the strategy formulation and explore the strategy evolution path.Practical implicationsThis study is a very insightful source of information about 3PLs in mainland China for logistics managers, investors and policy‐makers. It provides guidance for 3PLs executives to formulate logistics strategy, adjust business objectives and prioritize operations, and for logistics users to select appropriate logistics providers. There are also suggestions for government to improve the business environment for the logistics industry. The study provides a basis for research on logistics management in mainland China.Originality/valueThis study is a pioneer and comprehensive study of mainland China's 3PLs providers. To the best of our knowledge, this is the first study to examine 3PLs providers in mainland China.

Abstract
The membrane (M) protein is the most abundant structural protein of coronaviruses including MERS-CoV, SARS-CoV, and SARS-CoV-2, and plays a central role in virus assembly through its interaction with various partner proteins. However, mechanistic details about how M protein interacts with others remain elusive due to lack of high-resolution structures. Here, we present the first crystal structure of a betacoronavirus M protein from Pipistrellus bat coronavirus HKU5 (batCOV5-M), which is closely related to MERS-CoV, SARS-CoV, and SARS-CoV-2 M proteins. Furthermore, an interaction analysis indicates that the carboxy-terminus of the batCOV5 nucleocapsid (N) protein mediates its interaction with batCOV5-M. Combined with a computational docking analysis an M–N interaction model is proposed, providing insight into the mechanism of M protein–mediated protein interactions.