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Existing techniques for caching Web objects are not appropriate for the multimedia streaming service. In this paper, the authors focus on the proxy caching problem specifically for multimedia streaming objects. A prototype design and implementation of a proxy caching system – HUSTProxy is proposed. The main contribution of HUSTProxy is its ability of partial video caching, sending rate control and providing a more rational prefix caching size determination. These techniques are implemented in our design and are discussed in detail in this paper.

Objective: This study aims to investigate the crossing behavior of straight-moving drivers when they encounter other straight-moving drivers at unsignalized intersections in China. Background: In China, when two vehicle drivers encounter at an unsignalized intersection, neither driver completely stops his or her vehicle in most cases. Instead, one driver gradually approaches the intersection and dynamically decides to either yield or preempt by gaming with the other vehicle. This process increases the probability of accidents. Method: A total of 305 crossing cases were collected at an unsignalized intersection in Kunming City. Motion parameters were extracted from the video detection program designed by our research group. Based on a logistic regression method, we analyzed decision making moment of straight-moving drivers under crossing conditions, established crossing behavior models, and identified the main factors that affected drivers' decisions. In all, 68 cases observed at a separate intersection were used to validate the established models. Results: For crossing processes at unsignalized intersections in China, straight-moving drivers from the right side completed preemptive/yielding decisions at 1.3 s before reaching the crossing point. However, the majority of straight-moving drivers from the left side completed decisions at 1.1 s before reaching the crossing point. The most important parameter that influenced the drivers' decisions was the difference between the speeds of the two vehicles. Conclusion: An effective method for preventing traffic conflict between two straight-moving drivers is to control the speeds of the vehicles before they enter the intersection. Application: This study explores crossing behavior of straight-moving drivers and provides significant insights for controlling driver behavior.

To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Download ; A large fraction of genetic risk factors for Alzheimer's Disease (AD) is still not identified, limiting the understanding of AD pathology and study of therapeutic targets. We conducted a genome-wide association study (GWAS) of AD cases and controls of European descent from the multi-center DemGene network across Norway and two independent European cohorts. In a two-stage process, we first performed a meta-analysis using GWAS results from 2,893 AD cases and 6,858 cognitively normal controls from Norway and 25,580 cases and 48,466 controls from the International Genomics of Alzheimer's Project (IGAP), denoted the discovery sample. Second, we selected the top hits (p < 1 × 10 ; Research Council of Norway (RCN) EU JPND Program ApGeM RCN Grant South-East Norway Health Authority Norwegian Health Association KG Jebsen Foundation European Union European Community PIAPP-GA-2011-286213 PsychDPC French National Foundation on Alzheimer's disease and related disorders LABEX (laboratory of excellence program investment for the future) DISTALZ grant, Inserm, Institut Pasteur de Lille, Universite de Lille 2 Lille University Hospital Medical Research Council Alzheimer's Research UK Wellcome Trust German Federal Ministry of Education and Research (BMBF): Competence Network Dementia (CND) NIH/NIA NIA AGES NHLBI Icelandic Heart Association Erasmus Medical Center Erasmus University Alzheimer's Association