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Cover -- Half Title -- Title Page -- Copyright Page -- Dedication -- Table of Contents -- Acknowledgments -- Introduction -- 1 Constructing a Model of Republican Empires -- 2 Early Constitutional Structures -- 3 Creating the Imperial Constitution -- 4 The Struggle Over the Form, Character, and Direction of the New Empire -- 5 The Republican Empire of Conquest -- 6 Chief Justice John Marshall's Hamiltonian Empire: Turning Constitutional Conventions into Constitutional Law -- 7 Imperial Competition During the Ante-Belleum Era -- 8 John C. Calhoun, Dred Scott v. Sandford, and the Lincoln-Douglas Debates: Turning Constitutional Theories and Conventions into Constitutional Law -- 9 The Formation of the Modern American Empire -- Conclusion -- Bibiliography -- Index

Importance of estuaries -- Dymanamic role -- Scope of volume -- Suggested reading -- 1 The Estuary as a Resource -- 1.1 History of estuarine usage -- 1.2 Types and values of usage -- 1.3 Shipping -- 1.4 Domestic and industrial wastes -- 1.5 Fishing -- 1.6 Amenity -- 2 The Estuarine System -- 2.1 Estuarine classification -- 2.2 Sediment processes -- 2.3 Geochemical cycles -- 2.4 Primary production -- 2.5 Secondary pruduction -- 2.6 Energy flow -- 2.7 Environmental stresses -- 3 Impacts, Contamination and Pollution -- 3.1 Impacts -- 3.2 Contamination and pollution -- 3.3 Sewage and organic wastes -- 3.4 Heat -- 3.5 Hydrocarbons -- 3.6 Heavy metals -- 3.7 Organochlorines -- 3.8 Radioactivity -- 4 Effects and Detection -- 4.1 Indices -- 4.2 Biological indicators -- 4.3 Dose/response relationship -- 4.4 Community responses -- 4.5 Population responses -- 4.6 Individual responses -- 4.7 Cellular and sub-cellular responses -- 4.8 Overview -- 5 Management -- 5.1 Goals -- 5.2 Uniform Emission Standards and Best Available Technology -- 5.3 Environmental Quality Objective -- 5.4 Discharge Location -- 5.5 Environmental Quality Standards -- 5.6 International legislation -- 5.7 Future developments.

Section V: Maternal and Placental Effects -- 1 Maternal and Cytoplasmic Effects in Experimental Teratology -- 2 Factors That Affect Drug Concentrations in Maternal Plasma -- 3 Effects of Placental Pathology on the Embryo and Fetus -- Section VI: Comparative Studies in Man and Other Mammals -- 4 Summary of Comparative Embryology and Teratology -- 5 Comparative Placental Transfer -- Section VII: Epidemiology -- 6 Detection and Evaluation of Pregnancy Wastage -- 7 Value and Methods of Animal Studies in Epidemiology -- 8 Birth Defects Registries and Surveillance -- 9 Correlations of Malformation Frequency with Environmental and Genetic Attributes in Man.

Section I: Introduction -- 1 History of Teratology -- 2 Current Status of Teratology—General Principles and Mechanisms Derived From Animal Studies -- 3 Relation of Animal Studies to the Problem in Man -- Section II: Causes of Maldevelopment -- 4 Action of Mutagenic Agents -- 5 Radiations and Other Physical Agents -- 6 Infectious Diseases -- 7 Nutritional Deficiencies and Excesses -- 8 Embryotoxicity of Drugs in Man -- 9 Environmental Chemicals -- 10 Maternal Metabolic and Endocrine Imbalances -- 11 Atmospheric Gases—Variations in Concentration and Some Common Pollutants -- 12 Extremes of Temperature -- 13 Interactions and Multiple Causes.