Growth of mesenchymal stem cells on oriented microstructured films and electrospun scaffolds
In: Vestnik Moskovskogo universiteta. Seria 16. Biologia, Band 78, Heft №3s, 2023, S. 33-39
The study involved the fabrication of films with different roughness and scaffolds made of
poly(3-hydroxybutyrate) using various methods. Chaotic and oriented scaffolds with varying
fiber thickness were obtained through the electrospinning method, depending on the polymer
concentration and electrospinning parameters. Films with different surface roughness were
obtained using spin coating and self-assembly methods. It was demonstrated that the varying
microstructure of the surface does not affect the growth of mesenchymal stem cells over the
course of a week; however, it does influence the morphology of the adhered cells.