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In: Telos: critical theory of the contemporary, Volume 1979, Issue 42, p. 150-159
ISSN: 1940-459X
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In: Telos: critical theory of the contemporary, Volume 1979, Issue 42, p. 150-159
ISSN: 1940-459X
Environmental impacts of 15 European pig farming systems were evaluated in the European Union Q-PorkChains project using life cycle assessment. One conventional and two non-conventional systems were evaluated from each of the five countries: Denmark, The Netherlands, Spain, France and Germany. The data needed for calculations were obtained from surveys of 5 to 10 farms from each system. The systems studied were categorised into conventional (C), adapted conventional (AC), traditional (T) and organic (O). Compared with C systems, AC systems differed little, with only minor changes to improve meat quality, animal welfare or environmental impacts, depending on the system. The difference was much larger for T systems, using very fat, slow-growing traditional breeds and generally outdoor raising of fattening pigs. Environmental impacts were calculated at the farm gate and expressed per kg of pig live weight and per ha of land used. For C systems, impacts per kg LW for climate change, acidification, eutrophication, energy use and land occupation were 2.3 kg CO2-eq, 44.0 g SO2-eq, 18.5 g PO4-eq, 16.2 MJ and 4.1 m2, respectively. Compared with C, differences in corresponding mean values were +13%, +5%, 0%, +2% and +16% higher for AC; +54%, +79%, +23%, +50% and +156% for T, and +4%, -16%, +29%, +11% and +121% for O. Conversely, when expressed per ha of land use, mean impacts were 10% to 60% lower for T and O systems, depending on the impact category. This was mainly because of higher land occupation per kg of pig produced, owing to feed production and the outdoor raising of sows and/or fattening pigs. The use of straw bedding tended to increase climate change impact per kg LW. The use of traditional local breeds, with reduced productivity and feed efficiency, resulted in higher impacts per kg LW for all impact categories. T systems with extensive outdoor raising of pigs resulted in markedly lower impact per ha of land used. Eutrophication potential per ha was substantially lower for O systems. Conventional systems had ...
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In: Animal 12 (8), 2027-2037. (2014)
Environmental impacts of 15 European pig farming systems were evaluated in the European Union Q-PorkChains project using life cycle assessment. One conventional and two non-conventional systems were evaluated from each of the five countries: Denmark, The Netherlands, Spain, France and Germany. The data needed for calculations were obtained from surveys of 5 to 10 farms from each system. The systems studied were categorised into conventional (C), adapted conventional (AC), traditional (T) and organic (O). Compared with C systems, AC systems differed little, with only minor changes to improve meat quality, animal welfare or environmental impacts, depending on the system. The difference was much larger for T systems, using very fat, slow-growing traditional breeds and generally outdoor raising of fattening pigs. Environmental impacts were calculated at the farm gate and expressed per kg of pig live weight and per ha of land used. For C systems, impacts per kg LW for climate change, acidification, eutrophication, energy use and land occupation were 2.3 kg CO2-eq, 44.0 g SO2-eq, 18.5 g PO4-eq, 16.2 MJ and 4.1 m2, respectively. Compared with C, differences in corresponding mean values were +13%, +5%, 0%, +2% and +16% higher for AC; +54%, +79%, +23%, +50% and +156% for T, and +4%, -16%, +29%, +11% and +121% for O. Conversely, when expressed per ha of land use, mean impacts were 10% to 60% lower for T and O systems, depending on the impact category. This was mainly because of higher land occupation per kg of pig produced, owing to feed production and the outdoor raising of sows and/or fattening pigs. The use of straw bedding tended to increase climate change impact per kg LW. The use of traditional local breeds, with reduced productivity and feed efficiency, resulted in higher impacts per kg LW for all impact categories. T systems with extensive outdoor raising of pigs resulted in markedly lower impact per ha of land used. Eutrophication potential per ha was substantially lower for O systems. Conventional systems had lower global impacts (global warming, energy use, land use), expressed per kg LW, whereas differentiated systems had lower local impacts (eutrophication, acidification), expressed per ha of land use.
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This is the final version of the article. Available from Elsevier via the DOI in this record. ; Gene duplication is a major source of genetic variation that has been shown to underpin the evolution of a wide range of adaptive traits [1, 2]. For example, duplication or amplification of genes encoding detoxification enzymes has been shown to play an important role in the evolution of insecticide resistance [3–5]. In this context, gene duplication performs an adaptive function as a result of its effects on gene dosage and not as a source of functional novelty [3, 6–8]. Here, we show that duplication and neofunctionalization of a cytochrome P450, CYP6ER1, led to the evolution of insecticide resistance in the brown planthopper. Considerable genetic variation was observed in the coding sequence of CYP6ER1 in populations of brown planthopper collected from across Asia, but just two sequence variants are highly overexpressed in resistant strains and metabolize imidacloprid. Both variants are characterized by profound amino-acid alterations in substrate recognition sites, and the introduction of these mutations into a susceptible P450 sequence is sufficient to confer resistance. CYP6ER1 is duplicated in resistant strains with individuals carrying paralogs with and without the gain-of-function mutations. Despite numerical parity in the genome, the susceptible and mutant copies exhibit marked asymmetry in their expression with the resistant paralogs overexpressed. In the primary resistance-conferring CYP6ER1 variant, this results from an extended region of novel sequence upstream of the gene that provides enhanced expression. Our findings illustrate the versatility of gene duplication in providing opportunities for functional and regulatory innovation during the evolution of an adaptive trait. ; This project has received funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (grant agreement n°646625), the Biotechnology and Biological Sciences Research Council of the UK (BB/G023352/1), and Bayer Crop Science.
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This is the final version. Available from the publisher via the DOI in this record. ; There is an on-going need to develop new insecticides that are not compromised by resistance and that have improved environmental profiles. However, the cost of developing novel compounds has increased significantly over the last two decades. This is in part due to increased regulatory requirements, including the need to screen both pest and pollinator insect species to ensure that pre-existing resistance will not hamper the efficacy of a new insecticide via cross-resistance, or adversely affect non-target insect species. To add to this problem the collection and maintenance of toxicologically relevant pest and pollinator species and strains is costly and often difficult. Here we present Fly-Tox, a panel of publicly available transgenic Drosophila melanogaster lines each containing one or more pest or pollinator P450 genes that have been previously shown to metabolise insecticides. We describe the range of ways these tools can be used, including in predictive screens to avoid pre-existing cross-resistance, to identify potential resistance-breaking inhibitors, in the initial assessment of potential insecticide toxicity to bee pollinators, and identifying harmful pesticide-pesticide interactions. ; European Research Council (ERC) ; European Union's Horizon 2020 research and innovation programme ; Biotechnology and Biological Sciences Research Council (BBSRC)
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This is the final version of the article. Available from the publisher via the DOI in this record. ; The impact of neonicotinoid insecticides on the health of bee pollinators is a topic of intensive research and considerable current debate [1]. As insecticides, certain neonicotinoids, i.e., N-nitroguanidine compounds such as imidacloprid and thiamethoxam, are as intrinsically toxic to bees as to the insect pests they target. However, this is not the case for all neonicotinoids, with honeybees orders of magnitude less sensitive to N-cyanoamidine compounds such as thiacloprid [2]. Although previous work has suggested that this is due to rapid metabolism of these compounds [2, 3, 4, 5], the specific gene(s) or enzyme(s) involved remain unknown. Here, we show that the sensitivity of the two most economically important bee species to neonicotinoids is determined by cytochrome P450s of the CYP9Q subfamily. Radioligand binding and inhibitor assays showed that variation in honeybee sensitivity to N-nitroguanidine and N-cyanoamidine neonicotinoids does not reside in differences in their affinity for the receptor but rather in divergent metabolism by P450s. Functional expression of the entire CYP3 clade of P450s from honeybees identified a single P450, CYP9Q3, that metabolizes thiacloprid with high efficiency but has little activity against imidacloprid. We demonstrate that bumble bees also exhibit profound differences in their sensitivity to different neonicotinoids, and we identify CYP9Q4 as a functional ortholog of honeybee CYP9Q3 and a key metabolic determinant of neonicotinoid sensitivity in this species. Our results demonstrate that bee pollinators are equipped with biochemical defense systems that define their sensitivity to insecticides and this knowledge can be leveraged to safeguard bee health. ; his study received funding from Bayer AG. C.B. received funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (grant agreement no. 646625 ). C.B. and K.B. received funding from Biotechnology and Biological Sciences Research Council (BBSRC, award number 15076182 ). The work at Rothamsted forms part of the Smart Crop Protection (SCP) strategic programme ( BBS/OS/CP/000001 ) funded through the Biotechnology and Biological Sciences Research Council's Industrial Strategy Challenge Fund.
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Legumes Translated is a new thematic network in Horizon 2020. It supports the Agricultural European Innovation Partnership (EIP Agri) by linking research- and practice-based knowledge to support legume cropping and use. It is therefore in line with the recently announced European Protein Plan (European Commission 2018) that mentions a knowledge platform for protein crops. The overall goal is to support the production and use of grain legume crops in Europe as part of an overall change in protein sourcing and use (Donau Soja, 2017). The challenges that legumes crops can help address are well-documented: the need for more diversity in cropping with more crops that support pollinators; yield stagnation in cereal-dominated systems (e.g. Brisson et al., 2010; Watson et al., 2017); and a 29% deficit in tradable plant protein that is met by about 35 million tonnes of soybean equivalent imported from the Americas (Murphy-Bokern et al., 2017). This is a fundamental challenge to the resilience, acceptance and performance of our agri-food systems. There are indications that Europe is now on the cusp of a significant change manifest in the positive political response to the Donau Soja European Soya Declaration and the European Commission's work on Europe's protein balance. Thematic networks are a key element of the EIP Agri. funded from Horizon 2020. They complement both operational groups and Horizon 2020 research and innovation projects by compiling and validating existing knowledge and best practices and providing wider access to this knowledge with particular emphasis on trans-national border knowledge interaction. Legumes Translated has three underlying principles: empowerment of innovators through understanding; practice- and research-based sources of knowledge are mutually supportive; and cropping and farming system innovation must go hand-in-hand with corresponding value chain developments (especially in livestock).
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