Suchergebnisse

The EU Water Framework Directive (WFD) calls for cost-effective measures to achieve a "good status" in all European ground, surface and coastal waters. Besides eutrophication, the degradation of hydro-morphology is the main reason for failing the WFD's objectives in Germany. In this paper , we conceptualize the interactive decision support process BASINFORM-M for finding proper locations for river restora tion. The method combines the recently proposed "stepping stone concept" from aquatic ecology with elements from cost-effectiveness analysis, multi-criteria analysis and participatory approaches. BASINFORM-M exemplifies a shift away from the isolated resto ration of single river reaches to wards a consideration of functional relationships within the whole river network. In doing so, it satisfies the WFD's requirement of considering cost-effectiveness without neglecting other important evaluation criteria.

Platelet cryopreservation has been investigated for several decades as an alternative to room temperature storage of platelet concentrates. The use of dimethylsulfoxide as a cryoprotectant has improved platelet storage and cryopreserved concentrates can be kept at &minus ; 80 ° ; C for two years. Cryopreserved platelets can serve as emergency backup to support stock crises or to disburden difficult logistic areas like rural or military regions. Cryopreservation significantly influences platelet morphology, decreases platelet activation and severely abrogates platelet aggregation. Recent data indicate that cryopreserved platelets have a procoagulant phenotype because thrombin and fibrin formation kicks in earlier compared to room temperature stored platelets. This happens both in static and hydrodynamic conditions. In a clinical setting, low 1-h post transfusion recoveries of cryopreserved platelets represent fast clearance from circulation which may be explained by changes to the platelet GPIb&alpha ; receptor. Cryopreservation splits the concentrate in two platelet subpopulations depending on GPIb&alpha ; expression levels. Further research is needed to unravel its physiological importance. Proving clinical efficacy of cryopreserved platelets is difficult because of the heterogeneity of indications and the ambiguity of outcome measures. The procoagulant character of cryopreserved platelets has increased interest for use in trauma stressing the need for double-blinded randomized clinical trials in actively bleeding patients.

AbstractThe review examines the state of knowledge on genes that control the architectonics of wheat plant (spike morphology). It is shown that molecular genetic studies, which have been recently started, allow to find both the orthologous genes from relative species of wheat (barley, rye, etc.) and genes that were not previously used for breeding. Use of these genes for further breeding allows to produce modern wheat commercial cultivars.

Platelet cryopreservation has been investigated for several decades as an alternative to room temperature storage of platelet concentrates. The use of dimethylsulfoxide as a cryoprotectant has improved platelet storage and cryopreserved concentrates can be kept at −80 °C for two years. Cryopreserved platelets can serve as emergency backup to support stock crises or to disburden difficult logistic areas like rural or military regions. Cryopreservation significantly influences platelet morphology, decreases platelet activation and severely abrogates platelet aggregation. Recent data indicate that cryopreserved platelets have a procoagulant phenotype because thrombin and fibrin formation kicks in earlier compared to room temperature stored platelets. This happens both in static and hydrodynamic conditions. In a clinical setting, low 1-h post transfusion recoveries of cryopreserved platelets represent fast clearance from circulation which may be explained by changes to the platelet GPIbα receptor. Cryopreservation splits the concentrate in two platelet subpopulations depending on GPIbα expression levels. Further research is needed to unravel its physiological importance. Proving clinical efficacy of cryopreserved platelets is difficult because of the heterogeneity of indications and the ambiguity of outcome measures. The procoagulant character of cryopreserved platelets has increased interest for use in trauma stressing the need for double-blinded randomized clinical trials in actively bleeding patients.

This volume discusses a broad range of human welfare problems associated with and stemming from social issues, natural resource deficiencies, environmental hazards, vulnerability to climate change, and sustainability challenges. The chapters form a framework centered around the concept of social morphology, i.e. the role of humans in shaping society, and associated human-nature interactions which inform the ability to achieve sustainable welfare and well-being. The book is divided in six sections. Section I contains the introductory chapters where the book explores shifting interfaces between environment, society, and sustainability outcomes. Section II discusses contemporary issues of social welfare, and covers sustainable in geo-heritage and ecotourism. Section III addresses the roots of various social conflicts and inequalities in relation to overpopulation, poverty, illiteracy, employment concerns, and human migration. Section IV highlights social security and areas of social deprivation, including urban affordability, gender equality, and women's health. Section V covers social issues resulting from natural hazards and disasters. Section VI concludes the book with a discussion of the way forward for social sustainability. The book will be of interest to students, researchers, policy makers, environmentalists, NGOs, and social scientists.

International audience ; As opposed to many other track-and-field events, marathon performances still improve. We choose to better describe the reasons for such a progression. The 100 best marathon runners archived from January 1990 to December 2011 for men and from January 1996 to December 2011 for women were analysed. We determined the impact of historical, demographic, physiological, seasonal and environmental factors. Performances in marathons improve at every level of performance (deciles). In 2011, 94% of the 100 best men athletes were African runners; among women athletes they were 52%. Morphological indicators (stature, body mass and Body Mass Index (BMI)) have decreased. We show a parabolic function between BMI and running speed. The seasonal distribution has two peaks, in spring (weeks 14 to 17) and autumn (weeks 41 to 44). During both periods, the average temperature of the host cities varies close to optimal value for long distance race. African men and women runners are increasingly dominating the marathon and pushing its record, through optimal eco-physiological conditions.

Penelitian ini bertujuan menjelaskan (1) perkembangan morfologi fasade ruko, (2) faktor penyebab perubahan morfologi fasade ruko, dan (3) peran peraturan bangunan gedung yang berlaku dalam penentuan model fasade ruko di Mandonga. Penelitian ini dilaksanakan di Mandonga kota Kendari ibukota provinsi Sulawesi Tenggara. Metode yang digunakan dalam penelitian adalah survey lapangan dengan mewawancarai enambelas pemilik ruko sebagai responden dan melakukan perekaman visual. Pengambilan sampel dilakukan pada inti/pusat Mandonga yang paling berkembang melalui teknik sampling. Bertujuan menganalisis data dalam bentuk tabulasi yang kemudian di klasifikasikan untuk menjelaskan perubahan dan faktor yang mempengaruhi morfologi fasade ruko, dan melakukan penilaian terhadap fasade ruko sampel mengenai kesesuaian dengan peraturan/regulasi bangunan gedung dengan menggunakan skala Likert. Hasil penelitian menunjukkan bahwa morfologi fasade ruko di Mandonga cenderung berubah seiring perubahan waktu (trend gaya bangunan) dengan faktor sosial, ekonomi, budaya, ekologi, teknologi, politik dan hukum serta periode pembangunan ruko yang mempengaruhinya. Kata Kunci: Morfologi, fasade, rumah toko, regulasi