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This paper illustrates how the Analytic Guiding Frame (AGF) and the Overall Guiding Frame (OGF) are applied when analytic shifts occur in qualitative data analysis. Analytic shifts mainly occur when a proposed analytical method is found to be not fully amenable for analysis because of the contextually-bound nature of qualitative data. In this paper, the illustration located in the field of literacy education revolves around how a methodological and analytical problem was confronted during the fieldwork/analysis stage of research and how analytic negotiations were made with the help of the AGF/OGF framework. From here, it is proposed that much more consideration on matters of epistemology, methodology, research objective and research questions in qualitative research must be made when the iterative process of qualitative data analysis takes place.

Economic development requires knowledge in today's knowledge-based economy. The achievement of economic development in one area depends directly on the efficiency of the attainment, accumulation and application of knowledge and information. These processes rely heavily on the involvement of human resources with technological knowledge and technical skills. Correspondingly, knowledge creation ability and the efficiency of knowledge creation and application determine industrial clustering and economic sustainability. Current surveys of industrial clusters in Taiwan have ascertained that clusters of traditional industries do not necessarily lead to innovation although, empirically, an industrial cluster is a prerequisite for innovative activity. Recent studies have addressed the effects of the spatial proximity among firms and advanced research institutes in the Hsinchu area. According to their results, industrial clustering positively influences innovation by technological companies. Based on available results, this study considers how interaction between technological communities and industrial clustering influence the innovative activities in a sample area. Additionally, this study analyses social networking within the technological community and the relationship to industrial clustering in the Hsinchu area. Results of this study provide a valuable reference for industrial district planning and management.

AbstractWe study the problem of designing vaccine distribution strategies that maximally mitigate the negative impact of an infectious disease outbreak. This is achieved through a multiperiod optimization‐based framework that embeds important subject‐specific risk and contact information into the decision‐making process. By analyzing the structure of the resulting optimization problem, we identify key structural properties which we use to construct a globally convergent solution scheme (suitable for smaller problem instances) and two, more scalable, heuristic schemes. We demonstrate the benefits of the considered framework through a case study on COVID‐19 in Texas. Our results highlight the importance of considering risk and contact information as doing so substantially reduces the total expected number of fatalities over conventional compartmental‐based approaches. These findings indicate that customization can have a significant benefit, particularly for community‐scale planning.

Gender segregation in baccalaureate degree fields declined rapidly in the first half of the period from 1971 to 2002; at the same time, women's representation among baccalaureate degree recipients increased most rapidly relative to men's. The desegregation of the early period resulted mainly from women's increased entry into business-related fields and declining proportions of women majoring in traditional fields such as education and English. Men did not contribute to integration by moving toward fields numerically dominated by women. Fixed-effects regression models suggest that feminization of fields discourages later cohorts of men from entering them, as predicted by the devaluation perspective. The stalling of desegregation came from a combination of men's disinclination to enter fields that are "too" filled with women, and the slowdown in women making less traditional choices.

INTRODUCTION: In the primary care setting, proton pump inhibitor (PPI) overutilisation often stems from the failure to discontinue prophylaxis treatment prior to tertiary care discharge and consider step-down therapy following discharge. Long-term PPI use can result in potential drug-related problems and unnecessary drug expenditure. This study aimed to evaluate the effectiveness of pharmacist-structured review in reducing inappropriate PPI prescriptions and estimate the potential cost saving. METHODS: This non-randomised controlled study was conducted for 16 weeks at 17 government health clinics in Selangor, Malaysia. Eligible patients attending the outpatient pharmacies of intervention clinics were recruited consecutively and their consent was obtained. A structured review of PPIs was performed in which pharmacists identified patient demographics, indications and the length of PPI therapy using a PPI intervention form. Recommendations were discussed with physicians before prescription changes were made and documented. Moreover, standard management was conducted in the control clinics. RESULTS: A total of 568 patients with prescriptions containing PPIs were sampled, with a total of 284 patients being placed into the control and intervention groups, respectively. Compared to the control group, inappropriate PPI utilisation in the intervention group significantly decreased from 79.9 to 30.4% (p<0.05). The changes to PPI prescriptions observed in the intervention group included: stop PPI therapy (30.8%), step-down therapy (22.9%), start substitution therapy (15.9%) and no change (30.4%). The physicians' acceptance rate for pharmacist intervention was 67.8%. A 66.1% reduction in monthly PPI pill count and a 72.0% reduction in monthly medication expenditure (RM44.85/patient/year) were observed. CONCLUSION: The pharmacist-structured review was effective in increasing appropriate PPI utilisation and led to substantial cost savings.