The quest to find meaning in life is an integral part of human existence. Efforts to articulate how this is achievable can be traced back to the 6th-‐7th B.C.E., when Homer, Aristotle, Cicero and Virgil inquired about the means and goals of human nature. Informed by the social, political and economic transformations of their time, they proposed that bravery, conformity to the laws of the city, hard work, honesty, nobility, reason, and participation in the public affairs were values that encapsulated the good life. Although the relative importance of these values and their meanings have changed since then, their function to date remains tied to the processes of attainment, preservation or enhancement of living. ; N/A
Abstract. The meteorological model MM5 is applied operationally for the area of north-western Greece for one-year period (1 June 2007–31 May 2008). The model output is used for daily weather forecasting over the area. An early warning system is developed, by dividing the study area in 16 sub-regions and defining specific thresholds for issuing alerts for adverse weather phenomena. The verification of the model is carried out by comparing the model results with observations from three automatic meteorological stations. For air temperature and wind speed, correlation coefficients and biases are calculated, revealing that there is a significant overestimation of the early morning air temperature. For precipitation amount, yes/no contingency tables are constructed for 4 specific thresholds and some categorical statistics are applied, showing that the prediction of precipitation in the area under study is generally satisfactory. Finally, the thunderstorm warnings issued by the system are verified against the observed lightning activity.
Abstract. This paper presents RISKMED, a project targeted to create an Early Warning System (EWS) in case of severe or extreme weather events in the central and eastern Mediterranean and specifically in southern Italy, northwestern Greece, Malta and Cyprus. As severe or extreme weather events are considered, cases when the values of some meteorological parameters (temperature, wind, precipitation) exceed certain thresholds, and/or a severe weather phenomenon (thunderstorm, snowfall) occurs. For an accurate weather forecast, selected meteorological models have been operated daily, based on a nesting strategy using two or three domains, providing detailed forecasts over the above mentioned areas. The forecast results are further exploited for the evaluation and prediction of human discomfort and fire weather indices. Finally, sea wave models have also been operating daily over the central and eastern Mediterranean Sea. In case a severe or extreme weather event is forecasted within the next 48 or 72 h for selected target areas (sub-regions defined by their morphological and population characteristics), the local authorities and the public are informed via a user-friendly graphic system, the so-called RISK MAP. On the web page of the Project ( http://www.riskmed.net ), additional information is provided about the real-time values of some meteorological parameters, the latest satellite picture and the time and space distribution of lightning during the last 24 h. The RISKMED project was financed by the EU and th Ministries of National Economy of Greece, Italy, Malta and Cyprus, in the frame of INTERREG IIIB/ARCHIMED programme.
Background: The COVID-19 pandemic has disrupted routine hospital services globally. This study estimated the total number of adult elective operations that would be cancelled worldwide during the 12 weeks of peak disruption due to COVID-19. Methods: A global expert response study was conducted to elicit projections for the proportion of elective surgery that would be cancelled or postponed during the 12 weeks of peak disruption. A Bayesian β-regression model was used to estimate 12-week cancellation rates for 190 countries. Elective surgical case-mix data, stratified by specialty and indication (surgery for cancer versus benign disease), were determined. This case mix was applied to country-level surgical volumes. The 12-week cancellation rates were then applied to these figures to calculate the total number of cancelled operations. Results: The best estimate was that 28 404 603 operations would be cancelled or postponed during the peak 12 weeks of disruption due to COVID-19 (2 367 050 operations per week). Most would be operations for benign disease (90·2 per cent, 25 638 922 of 28 404 603). The overall 12-week cancellation rate would be 72·3 per cent. Globally, 81·7 per cent of operations for benign conditions (25 638 922 of 31 378 062), 37·7 per cent of cancer operations (2 324 070 of 6 162 311) and 25·4 per cent of elective caesarean sections (441 611 of 1 735 483) would be cancelled or postponed. If countries increased their normal surgical volume by 20 per cent after the pandemic, it would take a median of 45 weeks to clear the backlog of operations resulting from COVID-19 disruption. Conclusion: A very large number of operations will be cancelled or postponed owing to disruption caused by COVID-19. Governments should mitigate against this major burden on patients by developing recovery plans and implementing strategies to restore surgical activity safely.